<html xmlns="http://www.w3.org/1999/xhtml" xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office"><head><!--Required for Yahoo Mail app--></head><head><meta http-equiv="Content-Type" content="text/html; charset=utf-8">

        <meta name="Generator" content="Created with TOWER ONE Mail Designer">

        <meta name="Viewport" content="width=device-width, initial-scale=1.0">

        <style type="text/css" id="Mail Designer General Style Sheet">

        * { overflow-wrap: break-word; word-wrap: break-word; -ms-word-break: break-all; word-break: break-all; word-break: break-word; -ms-hyphens: auto; -moz-hyphens: auto; -webkit-hyphens: auto; hyphens: auto; }

                a img { border:none; }

                img { outline:none; text-decoration:none; -ms-interpolation-mode: bicubic; }

                body { width: 100% !important; -webkit-text-size-adjust: 100%; -ms-text-size-adjust: 100%; }

                .ExternalClass { width: 100%; }

                .ExternalClass, .ExternalClass p, .ExternalClass span, .ExternalClass font, .ExternalClass td, .ExternalClass div { line-height: 100%; }

                #page-wrap { margin: 0; padding: 0; width: 100% !important; line-height: 100% !important; }

                #outlook a { padding: 0; }

                .preheader { display:none !important; }

                a[x-apple-data-detectors] { color: inherit !important; text-decoration: none !important; font-size: inherit !important; font-family: inherit !important; font-weight: inherit !important; line-height: inherit !important; }

                .a5q { display: none !important; }

                .Apple-web-attachment { vertical-align: initial !important; }

                .Apple-edge-to-edge-visual-media { margin: initial !important; max-width: initial !important; width: 100%; }

                ul { margin-top: 0; margin-bottom: 0; padding-top: 0; padding-bottom: 0;}

                ol { margin-top: 0; margin-bottom: 0; padding-top: 0; padding-bottom: 0;}

        </style>

        <style type="text/css" id="Mail Designer Mobile Style Sheet">

                @media only screen and (max-width: 580px) {

                        table.email-body-wrap {

                                width: 375px!important;

                        }

                        td.page-bg-show-thru {

                                display: none!important;

                        }

                        table.layout-block-wrapping-table {

                                width: 375px!important;

                        }

                        table.mso-fixed-width-wrapping-table {

                                width: 375px!important;

                        }

                        .layout-block-full-width {

                                width: 375px!important;

                        }

                        table.layout-block-column, table.layout-block-padded-column {

                                width: 100% !important;

                        }

                        table.layout-block-box-padding {

                                width: 100% !important;

                                padding: 5px!important;

                        }

                        table.layout-block-horizontal-spacer {

                                display: none!important;

                        }

                        tr.layout-block-vertical-spacer {

                           display: block!important;

                           height: 8px!important;

                        }

                        td.container-padding {

                                display: none!important;

                        }

                        table {

                                min-width: initial!important;

                        }

                        td {

                                min-width: initial!important;

                        }

                        .desktop-only { display: none!important; }

                        .mobile-only { display: block!important; }

                        .hide {

                                max-height: none!important;

                                display: block!important;

                                overflow: visible!important;

                        }

                        .layout-block-table-desktop { display: none!important; }

                        .layout-block-table-mobile {

                                width: 100% !important;

                                display: block!important;

                        }

                        .md-table-spacer { height: 50px; }

                        #eqLayoutContainer {

                        }

                        table.no-padding-top { padding-top: 0!important; }

                        table.no-padding-right { padding-right: 0!important; }

                        table.no-padding-bottom { padding-bottom: 0!important; }

                        table.no-padding-left { padding-left: 0!important; }

                        .EQ-00 { width: 5px!important; }

                        .EQ-01 { width: 5px!important; }

                        .EQ-02 { width: 365px!important; }

                        .EQ-03 { width: 355px!important; height: 25px!important; }

                        .EQ-04 { width: 5px!important; }

                        .EQ-05 { width: 5px!important; }

                        .EQ-06 { width: 365px!important; }

                        .EQ-07 { height:5px!important; } 

                        .EQ-08 { width: 375px!important; }

                        .EQ-09 { width: 375px!important; height: 141px!important; }

                        .EQ-0A { width: 5px!important; }

                        .EQ-0B { width: 5px!important; }

                        .EQ-0C { width: 365px!important; }

                        .EQ-0D { height:5px!important; } 

                        .EQ-0E { width: 5px!important; }

                        .EQ-0F { width: 5px!important; }

                        .EQ-10 { width: 365px!important; }

                        .EQ-11 { width: 5px!important; }

                        .EQ-12 { width: 5px!important; }

                        .EQ-13 { width: 365px!important; }

                        .EQ-14 { width: 5px!important; }

                        .EQ-15 { width: 5px!important; }

                        .EQ-16 { width: 365px!important; }

                        .EQ-17 { height:5px!important; } 

                        .EQ-18 { width: 5px!important; }

                        .EQ-19 { width: 5px!important; }

                        .EQ-1A { width: 365px!important; }

                        .EQ-1B { width: 5px!important; }

                        .EQ-1C { width: 370px!important; }

                        .EQ-1D { width: 360px!important; height: 308px!important; }

                        .EQ-1E { width: 5px!important; }

                        .EQ-1F { width: 5px!important; }

                        .EQ-20 { width: 365px!important; }

                        .EQ-21 { height:5px!important; } 

                        .EQ-22 { width: 5px!important; }

                        .EQ-23 { width: 5px!important; }

                        .EQ-24 { width: 365px!important; }

                        .EQ-25 { width: 355px!important; height: 154px!important; }

                        .EQ-26 { width: 5px!important; }

                        .EQ-27 { width: 5px!important; }

                        .EQ-28 { width: 365px!important; }

                        .EQ-29 { height:5px!important; } 

                        .EQ-2A { width: 5px!important; }

                        .EQ-2B { width: 5px!important; }

                        .EQ-2C { width: 365px!important; }

                        .EQ-2D { width: 355px!important; height: 207px!important; }

                        .EQ-2E { width: 5px!important; }

                        .EQ-2F { width: 5px!important; }

                        .EQ-30 { width: 365px!important; }

                        .EQ-31 { height:5px!important; } 

                        .EQ-32 { width: 5px!important; }

                        .EQ-33 { width: 5px!important; }

                        .EQ-34 { width: 365px!important; }

                        .EQ-35 { width: 355px!important; height: 207px!important; }

                        .EQ-36 { width: 5px!important; }

                        .EQ-37 { width: 5px!important; }

                        .EQ-38 { width: 365px!important; }

                        .EQ-39 { height:5px!important; } 

                        .EQ-3A { width: 5px!important; }

                        .EQ-3B { width: 5px!important; }

                        .EQ-3C { width: 365px!important; }

                        .EQ-3D { width: 355px!important; height: 435px!important; }

                        .EQ-3E { width: 5px!important; }

                        .EQ-3F { width: 5px!important; }

                        .EQ-40 { width: 365px!important; }

                        .EQ-41 { height:5px!important; } 

                        .EQ-42 { width: 5px!important; }

                        .EQ-43 { width: 5px!important; }

                        .EQ-44 { width: 365px!important; }

                        .EQ-45 { height:5px!important; } 

                        .EQ-46 { width: 5px!important; }

                        .EQ-47 { width: 5px!important; }

                        .EQ-48 { width: 365px!important; }

                        .EQ-49 { width: 365px!important; height: 303px!important; }

                        .EQ-4A { width: 5px!important; }

                        .EQ-4B { width: 5px!important; }

                        .EQ-4C { width: 365px!important; }

                        .EQ-4D { height:5px!important; } 

                        .EQ-4E { width: 5px!important; }

                        .EQ-4F { width: 5px!important; }

                        .EQ-50 { width: 365px!important; }

                        .EQ-51 { width: 355px!important; height: 70px!important; }

                        .EQ-52 { width: 5px!important; }

                        .EQ-53 { width: 5px!important; }

                        .EQ-54 { width: 365px!important; }

                        .EQ-55 { width: 5px!important; }

                        .EQ-56 { width: 5px!important; }

                        .EQ-57 { width: 365px!important; }

                        .EQ-58 { width: 355px!important; height: 107px!important; }

                        .EQ-59 { width: 5px!important; }

                        .EQ-5A { width: 5px!important; }

                        .EQ-5B { width: 365px!important; }

                        .EQ-5C { width: 5px!important; }

                        .EQ-5D { width: 5px!important; }

                        .EQ-5E { width: 365px!important; }

                        .EQ-5F { height:5px!important; } 

                        .EQ-60 { width: 5px!important; }

                        .EQ-61 { width: 5px!important; }

                        .EQ-62 { width: 365px!important; }

                        .EQ-63 { width: 5px!important; }

                        .EQ-64 { width: 5px!important; }

                        .EQ-65 { width: 365px!important; }

                        .EQ-66 { width: 5px!important; }

                        .EQ-67 { width: 5px!important; }

                        .EQ-68 { width: 365px!important; }

                        .EQ-69 { width: 355px!important; height: 372px!important; }

                        .EQ-6A { width: 355px!important; height: 274px!important; }

                        .EQ-6B { width: 355px!important; height: 245px!important; }

                        .EQ-6C { width: 5px!important; }

                        .EQ-6D { width: 5px!important; }

                        .EQ-6E { width: 365px!important; }

                        .EQ-6F { height:5px!important; } 

                        .EQ-70 { width: 5px!important; }

                        .EQ-71 { width: 5px!important; }

                        .EQ-72 { width: 365px!important; }

                        .EQ-73 { width: 365px!important; height: 240px!important; }

                        .EQ-74 { width: 5px!important; }

                        .EQ-75 { width: 5px!important; }

                        .EQ-76 { width: 365px!important; }

                        .EQ-77 { height:5px!important; } 

                        .EQ-78 { width: 5px!important; }

                        .EQ-79 { width: 5px!important; }

                        .EQ-7A { width: 365px!important; }

                        .EQ-7B { width: 5px!important; }

                        .EQ-7C { width: 5px!important; }

                        .EQ-7D { width: 365px!important; }

                        .EQ-7E { width: 5px!important; }

                        .EQ-7F { width: 5px!important; }

                        .EQ-80 { width: 365px!important; }

                        .EQ-81 { height:5px!important; } 

                        .EQ-82 { width: 5px!important; }

                        .EQ-83 { width: 5px!important; }

                        .EQ-84 { width: 365px!important; }

                        .EQ-85 { width: 5px!important; }

                        .EQ-86 { width: 5px!important; }

                        .EQ-87 { width: 365px!important; }

                        .EQ-88 { width: 355px!important; height: 93px!important; }

                        .EQ-89 { width: 5px!important; }

                        .EQ-8A { width: 5px!important; }

                        .EQ-8B { width: 365px!important; }

                        .EQ-8C { height:5px!important; } 

                        .EQ-8D { width: 5px!important; }

                        .EQ-8E { width: 5px!important; }

                        .EQ-8F { width: 365px!important; }

                        .EQ-90 { width: 355px!important; height: 227px!important; }

                        .EQ-91 { width: 5px!important; }

                        .EQ-92 { width: 5px!important; }

                        .EQ-93 { width: 365px!important; }

                        .EQ-94 { height:5px!important; } 

                        .EQ-95 { width: 5px!important; }

                        .EQ-96 { width: 5px!important; }

                        .EQ-97 { width: 365px!important; }

                        .EQ-98 { width: 5px!important; }

                        .EQ-99 { width: 5px!important; }

                        .EQ-9A { width: 365px!important; }

                        .EQ-9B { height:5px!important; } 

                        .EQ-9C { width: 5px!important; }

                        .EQ-9D { width: 5px!important; }

                        .EQ-9E { width: 365px!important; }

                        .EQ-9F { width: 5px!important; }

                        .EQ-A0 { width: 5px!important; }

                        .EQ-A1 { width: 365px!important; }

                        .EQ-A2 { width: 375px!important; height: 155px!important; }

                        .EQ-A3 { width: 5px!important; }

                        .EQ-A4 { width: 5px!important; }

                        .EQ-A5 { width: 365px!important; }

                        .EQ-A6 { height:5px!important; } 

                        .EQ-A7 { width: 5px!important; }

                        .EQ-A8 { width: 5px!important; }

                        .EQ-A9 { width: 365px!important; }

                        .EQ-AA { width: 5px!important; }

                        .EQ-AB { width: 5px!important; }

                        .EQ-AC { width: 365px!important; }

                        .EQ-AD { height:5px!important; } 

                        .EQ-AE { width: 5px!important; }

                        .EQ-AF { width: 5px!important; }

                        .EQ-B0 { width: 365px!important; }

                        .EQ-B1 { width: 5px!important; }

                        .EQ-B2 { width: 5px!important; }

                        .EQ-B3 { width: 365px!important; }

                        .EQ-B4 { width: 355px!important; height: 248px!important; }

                        .EQ-B5 { width: 5px!important; }

                        .EQ-B6 { width: 5px!important; }

                        .EQ-B7 { width: 365px!important; }

                        .EQ-B8 { width: 5px!important; }

                        .EQ-B9 { width: 5px!important; }

                        .EQ-BA { width: 365px!important; }

                        .EQ-BB { height:5px!important; } 

                        .EQ-BC { width: 5px!important; }

                        .EQ-BD { width: 5px!important; }

                        .EQ-BE { width: 365px!important; }

                        .EQ-BF { width: 5px!important; }

                        .EQ-C0 { width: 5px!important; }

                        .EQ-C1 { width: 365px!important; }

                        .EQ-C2 { height:5px!important; } 

                        .EQ-C3 { width: 5px!important; }

                        .EQ-C4 { width: 5px!important; }

                        .EQ-C5 { width: 365px!important; }

                        .EQ-C6 { width: 5px!important; }

                        .EQ-C7 { width: 5px!important; }

                        .EQ-C8 { width: 365px!important; }

                        .EQ-C9 { width: 355px!important; height: 74px!important; }

                        .EQ-CA { width: 5px!important; }

                        .EQ-CB { width: 5px!important; }

                        .EQ-CC { width: 365px!important; }

                        .EQ-CD { width: 5px!important; }

                        .EQ-CE { width: 5px!important; }

                        .EQ-CF { width: 365px!important; }

                        .EQ-D0 { height:5px!important; } 

                        .EQ-D1 { width: 5px!important; }

                        .EQ-D2 { width: 5px!important; }

                        .EQ-D3 { width: 365px!important; }

                        .EQ-D4 { width: 5px!important; }

                        .EQ-D5 { width: 5px!important; }

                        .EQ-D6 { width: 365px!important; }

                        .EQ-D7 { height:5px!important; } 

                        .EQ-D8 { width: 5px!important; }

                        .EQ-D9 { width: 5px!important; }

                        .EQ-DA { width: 365px!important; }

                        .EQ-DB { width: 5px!important; }

                        .EQ-DC { width: 5px!important; }

                        .EQ-DD { width: 365px!important; }

                        .EQ-DE { width: 5px!important; }

                        .EQ-DF { width: 5px!important; }

                        .EQ-E0 { width: 365px!important; }

                        .EQ-E1 { height:5px!important; } 

                        .EQ-E2 { width: 5px!important; }

                        .EQ-E3 { width: 5px!important; }

                        .EQ-E4 { width: 365px!important; }

                        .EQ-E5 { height:5px!important; } 

                        .EQ-E6 { width: 5px!important; }

                        .EQ-E7 { width: 5px!important; }

                        .EQ-E8 { width: 365px!important; }

                        .EQ-E9 { width: 5px!important; }

                        .EQ-EA { width: 5px!important; }

                        .EQ-EB { width: 365px!important; }

                        .EQ-EC { height:5px!important; } 

                        .EQ-ED { width: 5px!important; }

                        .EQ-EE { width: 5px!important; }

                        .EQ-EF { width: 365px!important; }

                        .EQ-F0 { width: 365px!important; height: 250px!important; }

                        .EQ-F1 { width: 5px!important; }

                        .EQ-F2 { width: 5px!important; }

                        .EQ-F3 { width: 365px!important; }

                        .EQ-F4 { height:5px!important; } 

                        .EQ-F5 { width: 5px!important; }

                        .EQ-F6 { width: 5px!important; }

                        .EQ-F7 { width: 365px!important; }

                        .EQ-F8 { width: 5px!important; }

                        .EQ-F9 { width: 5px!important; }

                        .EQ-FA { width: 365px!important; }

                        .EQ-FB { width: 355px!important; height: 608px!important; }

                        .EQ-FC { width: 5px!important; }

                        .EQ-FD { width: 5px!important; }

                        .EQ-FE { width: 365px!important; }

                        .EQ-FF { height:5px!important; } 

                        .EQ-100 { width: 5px!important; }

                        .EQ-101 { width: 5px!important; }

                        .EQ-102 { width: 365px!important; }

                }

        </style>

        <!--[if gte mso 9]>

        <style type="text/css" id="Mail Designer Outlook Style Sheet">

                table.layout-block-horizontal-spacer {

                    display: none !important;

                }

                table {

                    border-collapse:collapse;

                    mso-table-lspace:0pt;

                    mso-table-rspace:0pt;

                    mso-table-bspace:0pt;

                    mso-table-tspace:0pt;

                    mso-padding-alt:0;

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<tr><td valign="top" class="layout-block-full-width"><div class="layout-block-image"><img height="300" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-1.png" border="0" style="line-height: 1px; display: block;"  class="img-EQMST-723507F3-28B8-40B7-82C8-7747B423BC46" width="800"></img><div style="width:0px;height:0px;max-height:0;max-width:0;overflow:hidden;display:none;visibility:hidden;mso-hide:all;"></div></div></td>

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                                                                                                                <i style="overflow-wrap: break-word; word-wrap: break-word; word-break: break-word; -webkit-hyphens: auto; font-family: Arial, sans-serif; font-size: 20px; font-weight: normal;">L’Edito</i>

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</tr></table></div></div></v:textbox></v:rect></td><td width="10" class="layout-block-padding-right">  </td>

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                                        <tbody><tr>

                                                <td width="10" class="EQ-11"> </td>

                                                <td width="780" class="EQ-13">

                                                        <table cellspacing="0" cellpadding="0" align="left" class="layout-block-column">

                                                                <tbody><tr>

                                                                        <td width="760" valign="top" align="left" background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" style="padding-left: 10px; padding-right: 10px;" bgcolor="#ffffff">

                                                                                <table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

                                                                                        <tbody><tr>

                                                                                                <td align="left" class="layout-block-column" width="760">

                                                                                                        <div  class="text" style="text-align: justify; font-size: 16px; font-family: 'Lucida Grande';"><div style="line-height: 14px;"><span style="font-size: 14px;"><font face="Arial, sans-serif">Bonjour à toutes et tous,</font></span></div><div style="line-height: 14px;">

<p style="margin: 0px;"><span style="font-size: 14px;"><font face="Arial, sans-serif">En ce début d’année 2019, je

profite de la diffusion de notre newsletter pour vous adresser à tous mes

meilleurs vœux de santé et réussite au nom de toute l’équipe de direction.

Cette année s’annonce riche en évènements pour la vie du laboratoire dont

certaines sont sources de tracas (comme les déménagements temporaires en

janvier pour la réalisation des travaux du plan campus) mais aussi porteurs de

nouveautés et de découvertes de nouvelles personnes, avant de voir se

concrétiser le projet réunissant toutes les équipes travaillant sur le campus

Lyon-Tech dans un nouveau bâtiment. </font></span></p><p style="margin: 0px;"><span style="font-size: 14px;"><font face="Arial, sans-serif">La réception des locaux de la <b>plateforme

PILoT </b>dans lesquels le <b>nouvel IRM 11,7T préclinique</b> sera installé et prévue

pour la fin de l’année marquera le lancement de cette nouvelle phase pour

<b>CREATIS</b>. L’autre évènement est la rédaction du bilan d’activité et

l’élaboration du projet scientifique de <b>CREATIS</b> (finalisation pour juin 2019)

en vue de l’évaluation des activités du laboratoire par <b>l’HCERES</b> et par <b>l’INSERM</b> :

que cette phase de concertation et de coopération soit pour nous l’opportunité

d’exposer toute la richesse et l’excellence de nos recherches, comme le

témoigne le contenu de cette newsletter.</font></span></p>

<p style="margin: 0px;"><span style="font-size: 14px;"><font face="Arial, sans-serif">Enfin, nous fêterons cette année

les <b>80 ans du CNRS.</b> C’est pour nous l’occasion de faire connaître la qualité de

la science Française ; et au-delà de souligner l’importance de défendre

les valeurs d’intégrité scientifique et de déontologie dans une période où la

‘communication’ peut prendre le pas sur le réel et où les fausses informations

doivent être combattues.</font></span></p>

<p style="margin: 0px;"><span style="font-size: 14px;"><font face="Arial, sans-serif">Très cordialement,</font></span></p>

<p style="margin: 0px;"><span style="font-size: 14px;"><font face="Arial, sans-serif">Olivier Beuf</font></span></p><p style="margin: 0px;"><br></p></div><div style="caret-color: rgb(0, 0, 0); font-family: -apple-system, BlinkMacSystemFont, sans-serif; font-size: 14px; text-align: start;"></div><div style="caret-color: rgb(0, 0, 0); font-family: -apple-system, BlinkMacSystemFont, sans-serif; font-size: 14px; text-align: start;"></div></div>

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                                                                                </tbody></table>

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                                        </tr>

                                </tbody></table>

                        <!--<![endif]--><!--[if gte mso 9]><div style="display:none;"><table cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" width="800">

<tr><td width="10" class="layout-block-padding-left">  </td><td width="780" class="layout-block-content-cell" valign="top" align="left"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

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<p style="margin: 0px;"><span style="font-size: 14px;"><font face="Arial, sans-serif">En ce début d’année 2019, je

profite de la diffusion de notre newsletter pour vous adresser à tous mes

meilleurs vœux de santé et réussite au nom de toute l’équipe de direction.

Cette année s’annonce riche en évènements pour la vie du laboratoire dont

certaines sont sources de tracas (comme les déménagements temporaires en

janvier pour la réalisation des travaux du plan campus) mais aussi porteurs de

nouveautés et de découvertes de nouvelles personnes, avant de voir se

concrétiser le projet réunissant toutes les équipes travaillant sur le campus

Lyon-Tech dans un nouveau bâtiment. </font></span></p><p style="margin: 0px;"><span style="font-size: 14px;"><font face="Arial, sans-serif">La réception des locaux de la <b>plateforme

PILoT </b>dans lesquels le <b>nouvel IRM 11,7T préclinique</b> sera installé et prévue

pour la fin de l’année marquera le lancement de cette nouvelle phase pour

<b>CREATIS</b>. L’autre évènement est la rédaction du bilan d’activité et

l’élaboration du projet scientifique de <b>CREATIS</b> (finalisation pour juin 2019)

en vue de l’évaluation des activités du laboratoire par <b>l’HCERES</b> et par <b>l’INSERM</b> :

que cette phase de concertation et de coopération soit pour nous l’opportunité

d’exposer toute la richesse et l’excellence de nos recherches, comme le

témoigne le contenu de cette newsletter.</font></span></p>

<p style="margin: 0px;"><span style="font-size: 14px;"><font face="Arial, sans-serif">Enfin, nous fêterons cette année

les <b>80 ans du CNRS.</b> C’est pour nous l’occasion de faire connaître la qualité de

la science Française ; et au-delà de souligner l’importance de défendre

les valeurs d’intégrité scientifique et de déontologie dans une période où la

‘communication’ peut prendre le pas sur le réel et où les fausses informations

doivent être combattues.</font></span></p>

<p style="margin: 0px;"><span style="font-size: 14px;"><font face="Arial, sans-serif">Très cordialement,</font></span></p>

<p style="margin: 0px;"><span style="font-size: 14px;"><font face="Arial, sans-serif">Olivier Beuf</font></span></p><p style="margin: 0px;"><br></p></div><div style="caret-color: #000000; font-family: sans-serif; font-size: 14px; text-align: start;"></div><div style="caret-color: #000000; font-family: sans-serif; font-size: 14px; text-align: start;"></div></div></td><td style="font-size:1px;" width="10">  </td>

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                                                                                <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande'; color: rgb(0, 0, 0);"><div style="text-align: justify;"><b style="font-size: 15px;"><font face="Arial, sans-serif">Installation du GADJETRON sur l’IRM 3T prisma du CHU de Saint-Etienne</font></b></div><div style="text-align: justify;"><font face="Arial, sans-serif" style="font-size: 13px;"><span style="text-align: start;">Vous pouvez trouver plus d'informations sur Gadgetron dans l'ouvrage Gadgetron: An Open Source Framework for Medical Image Reconstruction. Magn Reson Med 2013; 69:1768-1776. </span><a href="http://w99zwhhy.r.eu-west-1.awstrack.me/L0/http:%2F%2Fgadgetron.github.io/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/hQ4EP9LeoNrYmCP4Tz-xXEIolW8=96">http://gadgetron.github.io</a></font></div></div>

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                                                                                <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';"><p style="text-align: justify; margin: 0px; font-stretch: normal; line-height: normal;"><font face="Arial, sans-serif" style="font-size: 13px;">Le Gadgetron est un <b>cadre open source</b> pour la reconstruction d'images médicales. Il a été mis au point par l'<b>Institut national du cœur, des poumons et du sang, NIH, Bethesda, MD, États-Unis, et par le département d'informatique et le département de médecine clinique de l'Université d'Aarhus, au Danemark.</b> Il est mis gratuitement à la disposition de la communauté de la reconstruction d'images médicales.</font></p><p style="text-align: justify; margin: 0px; font-stretch: normal; line-height: normal;"><font face="Arial, sans-serif" style="font-size: 13px;">Si l’interfaçage avec l’imageur clinique demande un certain savoir-faire et le respect de principes de sécurité renforcé, sa mise en place offre des perspectives totalement nouvelles pour le transfert des méthodes de reconstruction avancées au plus près des besoins cliniques. </font></p><p style="text-align: justify; margin: 0px; font-stretch: normal; line-height: normal;"><font face="Arial, sans-serif" style="font-size: 13px;"><br></font></p><p style="text-align: justify; margin: 0px; font-stretch: normal; line-height: normal;"><font style="font-size: 13px;"><span style="font-family: Helvetica; text-align: start;">Gadgetron se base sur un format indépendant (ISMRM Raw Data). Cette solution inclut des convertisseurs de formats de données brutes de vendeurs spécifiques (Siemens, GE, Philips, Bruker, etc). Gadgetron permet également l'intégration d'infrastructures informatiques pour le calcul intensif (GPU et/ ou des CPU multi-core) au scanner IRM clinique. De plus, il est possible d'intégrer des méthodes computationnelles développées à partir d'outils scientifiques tels que MATLAB ou de frameworks open-source pour la reconstruction d'images comme BART.</span><br></font></p><p style="text-align: justify; margin: 0px; font-stretch: normal; line-height: normal;"><span style="font-family: Arial, sans-serif;"><font style="font-size: 13px;"><br></font></span></p><p style="text-align: justify; margin: 0px; font-stretch: normal; line-height: normal;"><font style="font-size: 13px;"><font face="Arial, sans-serif">Gadgetron, permettra aussi de renforcer les collaborations nationale avec les centres déjà équipés comme le <b>CRMBM Marseille </b>par ex. (un grand merci par ailleurs à <b>Stanislas Rapacchi, </b>ancien doctorant de <b>CREATIS, </b>pour l’entraide lors de l’installation!) </font><span style="font-family: Arial, sans-serif;">et pour le déploiement d’outils générique au sein du </span><b style="font-family: Arial, sans-serif;"><font face="Arial, sans-serif"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fremi.network/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/tiIjwJE3q1VDgyytXVQoluG-Irw=96">REMI</a></font>!</b><span style="font-family: Arial, sans-serif;"> </span></font></p></div>

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<tr><td rowspan="3" style="font-size:1px;" width="10">  </td><td class="layout-block-padded-column" width="399"><div class="text" style="font-size: 16px; font-family: sans-serif; color: #000000;"><div style="text-align: justify;"><b style="font-size: 15px;"><font face="Arial, sans-serif">Installation du GADJETRON sur l’IRM 3T prisma du CHU de Saint-Etienne</font></b></div><div style="text-align: justify;"><font face="Arial, sans-serif" style="font-size: 13px;"><span style="text-align: start;">Vous pouvez trouver plus d'informations sur Gadgetron dans l'ouvrage Gadgetron: An Open Source Framework for Medical Image Reconstruction. Magn Reson Med 2013; 69:1768-1776. </span><a href="http://w99zwhhy.r.eu-west-1.awstrack.me/L0/http:%2F%2Fgadgetron.github.io/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/Ik7VQIkQRgvV7nOiG0MigqeQ7uU=96">http://gadgetron.github.io</a></font></div></div></td><td rowspan="3" class="layout-block-horizontal-spacer" width="10">  </td><td rowspan="3" valign="top" align="left" class="layout-block-column" width="351"><div class="text" style="font-size: 16px; font-family: sans-serif;"><p style="text-align: justify; margin: 0px; font-stretch: normal; line-height: normal;"><font face="Arial, sans-serif" style="font-size: 13px;">Le Gadgetron est un <b>cadre open source</b> pour la reconstruction d'images médicales. Il a été mis au point par l'<b>Institut national du cœur, des poumons et du sang, NIH, Bethesda, MD, États-Unis, et par le département d'informatique et le département de médecine clinique de l'Université d'Aarhus, au Danemark.</b> Il est mis gratuitement à la disposition de la communauté de la reconstruction d'images médicales.</font></p><p style="text-align: justify; margin: 0px; font-stretch: normal; line-height: normal;"><font face="Arial, sans-serif" style="font-size: 13px;">Si l’interfaçage avec l’imageur clinique demande un certain savoir-faire et le respect de principes de sécurité renforcé, sa mise en place offre des perspectives totalement nouvelles pour le transfert des méthodes de reconstruction avancées au plus près des besoins cliniques. </font></p><p style="text-align: justify; margin: 0px; font-stretch: normal; line-height: normal;"><font face="Arial, sans-serif" style="font-size: 13px;"><br></font></p><p style="text-align: justify; margin: 0px; font-stretch: normal; line-height: normal;"><font style="font-size: 13px;"><span style="font-family: sans-serif; text-align: start;">Gadgetron se base sur un format indépendant (ISMRM Raw Data). Cette solution inclut des convertisseurs de formats de données brutes de vendeurs spécifiques (Siemens, GE, Philips, Bruker, etc). Gadgetron permet également l'intégration d'infrastructures informatiques pour le calcul intensif (GPU et/ ou des CPU multi-core) au scanner IRM clinique. De plus, il est possible d'intégrer des méthodes computationnelles développées à partir d'outils scientifiques tels que MATLAB ou de frameworks open-source pour la reconstruction d'images comme BART.</span><br></font></p><p style="text-align: justify; margin: 0px; font-stretch: normal; line-height: normal;"><span style="font-family: Arial, sans-serif;"><font style="font-size: 13px;"><br></font></span></p><p style="text-align: justify; margin: 0px; font-stretch: normal; line-height: normal;"><font style="font-size: 13px;"><font face="Arial, sans-serif">Gadgetron, permettra aussi de renforcer les collaborations nationale avec les centres déjà équipés comme le <b>CRMBM Marseille </b>par ex. (un grand merci par ailleurs à <b>Stanislas Rapacchi, </b>ancien doctorant de <b>CREATIS, </b>pour l’entraide lors de l’installation!) </font><span style="font-family: Arial, sans-serif;">et pour le déploiement d’outils générique au sein du </span><b style="font-family: Arial, sans-serif;"><font face="Arial, sans-serif"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fremi.network/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/3TruCzhYSWaw7aPMl5SWbqrj3pE=96">REMI</a></font>!</b><span style="font-family: Arial, sans-serif;"> </span></font></p></div></td><td style="font-size:1px;" width="10">  </td>

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                                                                                <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';"><b style="font-family: Helvetica; font-size: 15px;">Le cœur digital : Plateforme de génération de séquences cardiaques synthétiques réalistes en US & IRM</b></div>

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                                                                                <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';"><p style="text-align: justify; font-family: Helvetica; font-size: 12px;"><span lang="FR">Les travaux réalisés par Olivier Bernard et son équipe autour de la simulation réaliste du cœur à travers des outils intégrés dans <a moz-do-not-send="true" href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fvip.creatis.insa-lyon.fr%2F/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/rSxbH7dumt3qyeVt39sNIlKceyo=96">VIP</a> mis à l’honneur sur </span><a moz-do-not-send="true" href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.egi.eu%2F/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/4rXN2RdVwf-ehDgXb_jpKKTQfyw=96">EGI</a> : <a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.egi.eu%2Fuse-cases%2Fresearch-stories%2Fcreating-a-digital-heart%2F/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/rcpwz_WAbdu27aEqhFCH3-Os8gM=96">https://www.egi.eu/use-cases/research-stories/creating-a-digital-heart/</a></p><div style="text-align: justify; margin-top: 10px; margin-bottom: 10px; color: rgb(51, 51, 51); font-weight: 600; line-height: 1;"><span style="margin-top: 0px; margin-bottom: 0px;"><font face="Arial, sans-serif" style="font-size: 13px;"><i>"The generation of one full 3D sequence took around 6 hours on VIP, knowing that it would have taken over 280 hours on a personal laptop."</i></font></span></div><p style="text-align: justify; font-family: Helvetica; font-size: 12px;"><span lang="FR">L'article original IEEE TMI est disponible ici : <a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fhal.inria.fr%2Fhal-01533366%2Fdocument/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/_MW9ozdl-Ez3CRoS50j7q8Nl6nU=96">https://hal.inria.fr/hal-01533366/document</a>."</span></p><p style="text-align: justify; font-family: Helvetica; font-size: 12px;">Image legend: Multimodality heart simulations from the same virtual patient at frame 0 (ED), frame 5 and frame 10 (ES). The E/M meshes (i.e. ground truth segmentation) are superimposed as white contours.<span lang="FR">"</span></p></div>

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<tr><td width="10" class="layout-block-padding-left">  </td><td width="780" valign="top" align="left" class="layout-block-content-cell"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" align="left" class="layout-block-box-padding">

<tr><td rowspan="3" style="font-size:1px;" width="10">  </td><td class="layout-block-padded-column" width="462"><div class="text" style="font-size: 16px; font-family: sans-serif;"><b style="font-family: sans-serif; font-size: 15px;">Le cœur digital : Plateforme de génération de séquences cardiaques synthétiques réalistes en US & IRM</b></div></td><td rowspan="3" class="layout-block-horizontal-spacer" width="10">  </td><td rowspan="3" valign="top" align="left" class="layout-block-column" width="288"><div class="text" style="font-size: 16px; font-family: sans-serif;"><p style="text-align: justify; font-family: sans-serif; font-size: 12px;"><span lang="FR">Les travaux réalisés par Olivier Bernard et son équipe autour de la simulation réaliste du cœur à travers des outils intégrés dans <a moz-do-not-send="true" href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fvip.creatis.insa-lyon.fr%2F/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/PpRk4dSp-Hh_5wx2HXQLOzpECeg=96">VIP</a> mis à l’honneur sur </span><a moz-do-not-send="true" href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.egi.eu%2F/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/zch9AUvhd1cZlbiCZJzi3x7nWfw=96">EGI</a> : <a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.egi.eu%2Fuse-cases%2Fresearch-stories%2Fcreating-a-digital-heart%2F/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/7iAy4YilRpu7idhq-AW3gjbjc04=96">https://www.egi.eu/use-cases/research-stories/creating-a-digital-heart/</a></p><div style="text-align: justify; color: #333333; font-weight: 600; line-height: 100%;"><p style="padding: 0px; margin: 10px 0px;"><span style="margin-top: 0px; margin-bottom: 0px;"><font face="Arial, sans-serif" style="font-size: 13px;"><i>"The generation of one full 3D sequence took around 6 hours on VIP, knowing that it would have taken over 280 hours on a personal laptop."</i></font></span></p></div><p style="text-align: justify; font-family: sans-serif; font-size: 12px;"><span lang="FR">L'article original IEEE TMI est disponible ici : <a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fhal.inria.fr%2Fhal-01533366%2Fdocument/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/K5HEieLn5jbz5Hv6O4g0n0ULNPI=96">https://hal.inria.fr/hal-01533366/document</a>."</span></p><p style="text-align: justify; font-family: sans-serif; font-size: 12px;">Image legend: Multimodality heart simulations from the same virtual patient at frame 0 (ED), frame 5 and frame 10 (ES). The E/M meshes (i.e. ground truth segmentation) are superimposed as white contours.<span lang="FR">"</span></p></div></td><td style="font-size:1px;" width="10">  </td>

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                                <!--[if !mso 15]><!--><table width="800" cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" style="mso-hide:all;">

                                        <tbody><tr>

                                                <td width="10" class="EQ-2A"> </td>

                                                <td width="780" valign="top" align="left" background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" class="EQ-2C" bgcolor="#ffffff">

                                                        <table cellspacing="0" cellpadding="0" align="left" style="padding-left: 10px;" class="layout-block-box-padding">

                                                                <tbody><tr>

                                                                        <td class="layout-block-column" width="389">

                                                                                <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande'; color: rgb(0, 0, 0);"><div style="text-align: justify; line-height: 1;"><b style="font-size: 15px;"><font face="Arial, sans-serif">Application de visualisation d'images médicales 3D open source via un navigateur</font></b></div><div style="text-align: justify; line-height: 1;"><b style="font-size: 14px;"><font face="Arial, sans-serif"><br></font></b></div><div style="text-align: justify; line-height: 1;"><span style="font-size: 14px;"><font face="Arial, sans-serif"><span style="text-align: -webkit-left;">Téléchargez sur webVV : </span><font style="text-align: -webkit-left;"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fopen-vv.github.io/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/FO4z7JdqqksGuMz7HFjxLBynxrc=96">https://open-vv.github.io</a></font></font></span></div></div>

                                                                        </td>

                                                                </tr>

                                                                <tr class="layout-block-vertical-spacer" style="display:block; height:8px;">

                                                                        <td width="389"><div class="spacer"></div></td>

                                                                </tr>

                                                                <tr>

                                                                        <td class="layout-block-padded-column" align="center" width="389">

                                                                                <div class="layout-block-image">

                                                                                        <img width="389" height="227" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-15.png" border="0" style="line-height: 1px; display: block; width: 389px; height: 227px;" class="EQ-2D">

                                                                                </div>

                                                                        </td>

                                                                </tr>

                                                        </tbody></table>

                                                        <table width="10" cellspacing="0" cellpadding="0" align="left" class="layout-block-horizontal-spacer">

                                                                <tbody><tr>

                                                                        <td width="10" class="layout-block-horizontal-spacer" style="line-height:1px;"> </td>

                                                                </tr>

                                                        </tbody></table>

                                                        <table cellspacing="0" cellpadding="0" align="left" style="padding-right: 10px;" class="layout-block-box-padding">

                                                                <tbody><tr class="layout-block-vertical-spacer" style="display:none; height:0px;">

                                                                        <td width="361"><div class="spacer"></div></td>

                                                                </tr>

                                                                <tr>

                                                                        <td valign="top" align="left" class="layout-block-column" width="361">

                                                                                <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';"><p style="text-align: justify; margin: 0px; font-stretch: normal; line-height: normal;"><font face="Arial, sans-serif"><font style="text-align: -webkit-left; font-size: 13px;"> </font><span style="text-align: -webkit-left; font-size: 13px;">Cette application, developpée durant le stage de master 1 de </span><font style="text-align: -webkit-left; font-size: 13px;"><b>Lucas OUANICHE</b> </font><span style="text-align: -webkit-left; font-size: 13px;">est disponible à tous et ne nécessite aucune installation: il suffit de se connecter avec un navigateur sur l'adresse ci-dessus puis de choisir une image de votre ordinateur pour l'afficher. </span></font></p><div style="text-align: justify; "><span style="font-size: 13px;"><font face="Arial, sans-serif"><br></font></span></div><div><div style="text-align: justify;"><span style="font-family: Arial, sans-serif; font-size: 13px;">L'application permet de visualiser des volumes 3D (dicom, nifti, mhd/raw, ...), de changer de slice, de fenêtrage, d'orientation, d'ajouter un overlay, une fusion ou des structures, de mesurer des distances ... Le principe est de rester simple (pas de traitement), mais rapide.</span></div><div><div style="text-align: justify;"><font face="Arial, sans-serif" style="font-size: 13px;"><br></font></div><div style="text-align: justify;"><font face="Arial, sans-serif" style="font-size: 13px;">Sous le capot, tout est écrit en Javascript et basé sur la librairie AMI (<a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fgithub.com%2FFNNDSC%2Fami/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/DpcY8Uf9XWo1KxGKt2aRUKxhM1c=96">https://github.com/FNNDSC/ami</a>), aucune image n'est transférée ni stockée sur les serveurs, même temporairement. Si vous avez des remarques, suggestions ou que vous rencontrez des problèmes ou des bugs, contacter: </font></div></div><div style="text-align: justify; "><font style="font-size: 13px;" face="Arial, sans-serif"><a href="mailto:thomas.baudier@creatis.insa-lyon.fr">thomas.baudier@creatis.insa-lyon.fr</a></font></div></div><p style="text-align: justify; margin: 0px; font-stretch: normal; line-height: normal;"><br></p></div>

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                                                </td>

                                                <td width="10" class="EQ-2B"> </td>

                                        </tr>

                                </tbody></table>

                        <!--<![endif]--><!--[if gte mso 9]><div style="display:none;"><table cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" width="800">

<tr><td width="10" class="layout-block-padding-left">  </td><td width="780" valign="top" align="left" class="layout-block-content-cell"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" align="left" class="layout-block-box-padding">

<tr><td rowspan="3" style="font-size:1px;" width="10">  </td><td class="layout-block-padded-column" width="389"><div class="text" style="font-size: 16px; font-family: sans-serif; color: #000000;"><div style="text-align: justify; line-height: 100%;"><b style="font-size: 15px;"><font face="Arial, sans-serif">Application de visualisation d'images médicales 3D open source via un navigateur</font></b></div><div style="text-align: justify; line-height: 100%;"><b style="font-size: 14px;"><font face="Arial, sans-serif"><br></font></b></div><div style="text-align: justify; line-height: 100%;"><span style="font-size: 14px;"><font face="Arial, sans-serif"><span style="text-align: -webkit-left;">Téléchargez sur webVV : </span><font style="text-align: -webkit-left;"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fopen-vv.github.io/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/QBTnXC22rVe9cBa9B7TaZHpLxSY=96">https://open-vv.github.io</a></font></font></span></div></div></td><td rowspan="3" class="layout-block-horizontal-spacer" width="10">  </td><td rowspan="3" valign="top" align="left" class="layout-block-column" width="361"><div class="text" style="font-size: 16px; font-family: sans-serif;"><p style="text-align: justify; margin: 0px; font-stretch: normal; line-height: normal;"><font face="Arial, sans-serif"><font style="text-align: -webkit-left; font-size: 13px;"> </font><span style="text-align: -webkit-left; font-size: 13px;">Cette application, developpée durant le stage de master 1 de </span><font style="text-align: -webkit-left; font-size: 13px;"><b>Lucas OUANICHE</b> </font><span style="text-align: -webkit-left; font-size: 13px;">est disponible à tous et ne nécessite aucune installation: il suffit de se connecter avec un navigateur sur l'adresse ci-dessus puis de choisir une image de votre ordinateur pour l'afficher. </span></font></p><div style="text-align: justify;"><span style="font-size: 13px;"><font face="Arial, sans-serif"><br></font></span></div><div><div style="text-align: justify;"><span style="font-family: Arial, sans-serif; font-size: 13px;">L'application permet de visualiser des volumes 3D (dicom, nifti, mhd/raw, ...), de changer de slice, de fenêtrage, d'orientation, d'ajouter un overlay, une fusion ou des structures, de mesurer des distances ... Le principe est de rester simple (pas de traitement), mais rapide.</span></div><div><div style="text-align: justify;"><font face="Arial, sans-serif" style="font-size: 13px;"><br></font></div><div style="text-align: justify;"><font face="Arial, sans-serif" style="font-size: 13px;">Sous le capot, tout est écrit en Javascript et basé sur la librairie AMI (<a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fgithub.com%2FFNNDSC%2Fami/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/XE6vKawPeDQmeQQ7XFbuAKBwfuI=96">https://github.com/FNNDSC/ami</a>), aucune image n'est transférée ni stockée sur les serveurs, même temporairement. Si vous avez des remarques, suggestions ou que vous rencontrez des problèmes ou des bugs, contacter: </font></div></div><div style="text-align: justify;"><font style="font-size: 13px;" face="Arial, sans-serif"><a href="mailto:thomas.baudier@creatis.insa-lyon.fr">thomas.baudier@creatis.insa-lyon.fr</a></font></div></div><p style="text-align: justify; margin: 0px; font-stretch: normal; line-height: normal;"><br></p></div></td><td style="font-size:1px;" width="10">  </td>

</tr><tr class="layout-block-vertical-spacer" style="display:block; height:8px;"><td><div class="spacer"></div></td>

</tr><tr><td class="layout-block-padded-column" align="center" width="389"><div class="layout-block-image"><img height="227" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-15.png" border="0" style="line-height: 1px; display: block;"  class="img-EQMST-E5F7B6D7-C37D-419D-B5A0-E3F57AED6C5B" width="389"></img><div style="width:0px;height:0px;max-height:0;max-width:0;overflow:hidden;display:none;visibility:hidden;mso-hide:all;"></div></div></td>

</tr></table></div></div></v:textbox></v:rect></td><td width="10" class="layout-block-padding-right">  </td>

</tr></table></div><![endif]--></div>

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                                <!--[if !mso 15]><!--><table width="800" cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" style="mso-hide:all;">

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                                                <td width="10" class="EQ-2E" style="font-size:1px;"> </td>

                                                <td height="10" background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-70.jpg" class="EQ-30" bgcolor="#ffffff" width="780">

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<tr><td width="10" class="layout-block-padding-left" style="font-size:0">  </td><td class="layout-block-content-cell" style="font-size:0;" width="780" height="10"><v:rect style="width:780px;height:10px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-70.jpg" color="#ffffff"></v:fill><div class="spacer"></div></v:rect></td><td width="10" class="layout-block-padding-right" style="font-size:0">  </td>

</tr></table></div><![endif]--></div>

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                                <!--[if !mso 15]><!--><table width="800" cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" style="mso-hide:all;">

                                        <tbody><tr>

                                                <td width="10" class="EQ-32"> </td>

                                                <td width="780" valign="top" align="left" background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" class="EQ-34" bgcolor="#ffffff">

                                                        <table cellspacing="0" cellpadding="0" align="left" style="padding-left: 10px;" class="layout-block-box-padding">

                                                                <tbody><tr>

                                                                        <td class="layout-block-column" width="389">

                                                                                <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande'; color: rgb(0, 0, 0);"><div style="text-align: justify; line-height: 1;"><b style="font-family: Helvetica; font-size: 15px;">Finali</b><span style="font-size: 15px;"><font face="Arial, sans-serif"><b style="line-height: 1;">s</b><b><span style="line-height: 1;">te </span>"Young Investigator Award" de MICCAI 2018.</b></font></span></div><div style="text-align: justify;"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Flink.springer.com%2Fchapter%2F10.1007%2F978-3-030-00931-1_68/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/V8yMQtKbyxpeefKPG5-Bms1n3V0=96" style="font-family: Helvetica; font-size: 12px; text-align: start;">https://link.springer.com/chapter/10.1007/978-3-030-00931-1_68</a></div></div>

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                                                                                <div class="layout-block-image">

                                                                                        <img width="389" height="227" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-4.png" border="0" style="line-height: 1px; display: block; width: 389px; height: 227px;" class="EQ-35">

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                                                        <table width="10" cellspacing="0" cellpadding="0" align="left" class="layout-block-horizontal-spacer">

                                                                <tbody><tr>

                                                                        <td width="10" class="layout-block-horizontal-spacer" style="line-height:1px;"> </td>

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                                                        <table cellspacing="0" cellpadding="0" align="left" style="padding-right: 10px;" class="layout-block-box-padding">

                                                                <tbody><tr class="layout-block-vertical-spacer" style="display:none; height:0px;">

                                                                        <td width="361"><div class="spacer"></div></td>

                                                                </tr>

                                                                <tr>

                                                                        <td valign="top" align="left" class="layout-block-column" width="361">

                                                                                <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';"><p style="text-align: justify; margin: 0px; font-stretch: normal; line-height: normal;"><span style="font-family: Helvetica; font-size: 12px; text-align: start;"><b>Pierre-Antoine Ganaye, </b>doctorant encadré par <b>M Sdika et H Benoit-Cattin</b> a été retenu dans la <b>"short-list"</b> pour le <b>"Young Investigator Award" de MICCAI 2018.</b> </span><span style="font-family: Helvetica; font-size: 12px;">Ce  travail  est  arrivé en finale de la compétition et i</span><span style="font-family: Helvetica; font-size: 12px; text-align: start;">l s'en est fallu de très peu pour qu'il obtienne cette récompense!</span></p><p style="text-align: start; margin: 0px; font-stretch: normal; line-height: normal;"><span style="font-family: Helvetica; font-size: 12px; text-align: start;"><b>Méthode:</b></span></p><p style="text-align: justify; margin: 0px; font-stretch: normal; line-height: normal;"><span style="font-family: Helvetica; font-size: 12px; text-align: start;">En  combinant  la  puissance  des  modèles  issus  de l’intelligence  artificielle et notre expertise en traitement d’images, nous avons  repoussé les limites atteintes par les approches classiques. Nous avons ainsi proposé une méthode de segmentation des structures cérébrales  fondée  sur  des techniques  d’apprentissage  profond.  L’originalité  de  la méthode  consiste  à  intégrer  à  l’apprentissage  classique un a priori anatomique : deux structures ne peuvent être adjacentes que si c’est anatomiquement possible. Cette méthode de segmentation par apprentissage profond sous contrainte a permis de réduire d’un facteur deux l’erreur maximum de segmentation et de  quasiment supprimer  les  erreurs  anatomiques.  </span></p></div>

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<tr><td width="10" class="layout-block-padding-left">  </td><td width="780" valign="top" align="left" class="layout-block-content-cell"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" align="left" class="layout-block-box-padding">

<tr><td rowspan="3" style="font-size:1px;" width="10">  </td><td class="layout-block-padded-column" width="389"><div class="text" style="font-size: 16px; font-family: sans-serif; color: #000000;"><div style="text-align: justify; line-height: 100%;"><b style="font-family: sans-serif; font-size: 15px;">Finali</b><span style="font-size: 15px;"><font face="Arial, sans-serif"><b style="line-height: 100%;">s</b><b><span style="line-height: 100%;">te </span>"Young Investigator Award" de MICCAI 2018.</b></font></span></div><div style="text-align: justify;"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Flink.springer.com%2Fchapter%2F10.1007%2F978-3-030-00931-1_68/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/1PqazOuJjpR80EOYBpZmSelzlO4=96" style="font-family: sans-serif; font-size: 12px; text-align: start;">https://link.springer.com/chapter/10.1007/978-3-030-00931-1_68</a></div></div></td><td rowspan="3" class="layout-block-horizontal-spacer" width="10">  </td><td rowspan="3" valign="top" align="left" class="layout-block-column" width="361"><div class="text" style="font-size: 16px; font-family: sans-serif;"><p style="text-align: justify; margin: 0px; font-stretch: normal; line-height: normal;"><span style="font-family: sans-serif; font-size: 12px; text-align: start;"><b>Pierre-Antoine Ganaye, </b>doctorant encadré par <b>M Sdika et H Benoit-Cattin</b> a été retenu dans la <b>"short-list"</b> pour le <b>"Young Investigator Award" de MICCAI 2018.</b> </span><span style="font-family: sans-serif; font-size: 12px;">Ce  travail  est  arrivé en finale de la compétition et i</span><span style="font-family: sans-serif; font-size: 12px; text-align: start;">l s'en est fallu de très peu pour qu'il obtienne cette récompense!</span></p><p style="text-align: start; margin: 0px; font-stretch: normal; line-height: normal;"><span style="font-family: sans-serif; font-size: 12px; text-align: start;"><b>Méthode:</b></span></p><p style="text-align: justify; margin: 0px; font-stretch: normal; line-height: normal;"><span style="font-family: sans-serif; font-size: 12px; text-align: start;">En  combinant  la  puissance  des  modèles  issus  de l’intelligence  artificielle et notre expertise en traitement d’images, nous avons  repoussé les limites atteintes par les approches classiques. Nous avons ainsi proposé une méthode de segmentation des structures cérébrales  fondée  sur  des techniques  d’apprentissage  profond.  L’originalité  de  la méthode  consiste  à  intégrer  à  l’apprentissage  classique un a priori anatomique : deux structures ne peuvent être adjacentes que si c’est anatomiquement possible. Cette méthode de segmentation par apprentissage profond sous contrainte a permis de réduire d’un facteur deux l’erreur maximum de segmentation et de  quasiment supprimer  les  erreurs  anatomiques.  </span></p></div></td><td style="font-size:1px;" width="10">  </td>

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                                                                        <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';"><p style="margin-top: 0in; margin-bottom: 0.0001pt;"><span style="font-size: 15px;"><font face="Arial, sans-serif"><span lang="FR"><font style="font-size: 16px; font-weight: bold;">Réception et mise en service du </font></span><b>scanner spectral PHILIPS</b></font></span></p><p style="margin-top: 0in; margin-bottom: 0.0001pt;"><span style="font-size: 15px;"><font face="Arial, sans-serif"><b><br></b></font></span></p><p style="margin-top: 0in; margin-bottom: 0.0001pt;"><span lang="FR"><font face="Arial, sans-serif" style="font-size: 13px;">Dans le cadre du <b>projet européen H2020 SPCCT</b>, le nouveau prototype de <b>scanner spectral PHILIPS</b> a été livré et installé au <b>CERMEP</b> début décembre 2018.</font></span></p><p style="margin-top: 0in; margin-bottom: 0.0001pt;"><font face="Arial, sans-serif" style="font-size: 13px;">Equipé de la <b>dernière génération de détecteurs CZT,</b> cet équipement offre un champs de vue étendu à 500mm et une couverture /Z plus large (~20mm) (contre 2.5mm auparavant) –ce qui permettra d’imager des sujets de taille humain. Doté également d’un algorithme de reconstruction d’image amélioré et permettant désormais de traiter des images de plus grande taille pour une meilleure détection et une plus grande sensibilité spectrale.</font></p><p style="margin-top: 0in; margin-bottom: 0.0001pt;"><font face="Arial, sans-serif" style="font-size: 13px;">Nous attendons avec impatience les vérifications du scanner et l’autorisation d’utilisation pour poursuivre les travaux de recherche, lesquels devraient apporter des résultats innovants autant du point de vue technologique que du point de vue clinique. </font></p></div>

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<tr><td width="10" class="layout-block-padding-left">  </td><td width="780" class="layout-block-content-cell"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" align="left" class="layout-block-padded-column">

<tr><td valign="top" align="left" class="layout-block-padded-column" width="614"><div class="text" style="font-size: 16px; font-family: sans-serif;"><p style="margin-top: 0in; margin-bottom: 0.0001pt;"><span style="font-size: 15px;"><font face="Arial, sans-serif"><span lang="FR"><font style="font-size: 16px; font-weight: bold;">Réception et mise en service du </font></span><b>scanner spectral PHILIPS</b></font></span></p><p style="margin-top: 0in; margin-bottom: 0.0001pt;"><span style="font-size: 15px;"><font face="Arial, sans-serif"><b><br></b></font></span></p><p style="margin-top: 0in; margin-bottom: 0.0001pt;"><span lang="FR"><font face="Arial, sans-serif" style="font-size: 13px;">Dans le cadre du <b>projet européen H2020 SPCCT</b>, le nouveau prototype de <b>scanner spectral PHILIPS</b> a été livré et installé au <b>CERMEP</b> début décembre 2018.</font></span></p><p style="margin-top: 0in; margin-bottom: 0.0001pt;"><font face="Arial, sans-serif" style="font-size: 13px;">Equipé de la <b>dernière génération de détecteurs CZT,</b> cet équipement offre un champs de vue étendu à 500mm et une couverture /Z plus large (~20mm) (contre 2.5mm auparavant) –ce qui permettra d’imager des sujets de taille humain. Doté également d’un algorithme de reconstruction d’image amélioré et permettant désormais de traiter des images de plus grande taille pour une meilleure détection et une plus grande sensibilité spectrale.</font></p><p style="margin-top: 0in; margin-bottom: 0.0001pt;"><font face="Arial, sans-serif" style="font-size: 13px;">Nous attendons avec impatience les vérifications du scanner et l’autorisation d’utilisation pour poursuivre les travaux de recherche, lesquels devraient apporter des résultats innovants autant du point de vue technologique que du point de vue clinique. </font></p></div></td><td class="layout-block-horizontal-spacer" width="10">  </td><td width="156" valign="top" class="layout-block-padded-column" align="center"><div class="layout-block-image"><img height="191" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-17.jpg" border="0" style="display: block;"  class="img-EQMST-7A413A41-6D6E-45AC-A25A-4CAC0C61422D" width="156"></img><div style="width:0px;height:0px;max-height:0;max-width:0;overflow:hidden;display:none;visibility:hidden;mso-hide:all;"></div></div></td>

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                                                                                <div  class="heading" align="left" style="font-size: 16px; font-family: 'Lucida Grande';"><b><font face="Arial"> François Varray: Titulaire de l’HDR </font></b></div>

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<p style="text-align: justify; line-height: 1;"><font face="Arial, sans-serif" style="line-height: 1; font-size: 13px;">Arrivé à Creatis en septembre 2008 pour effectuer sa thèse de doctorat,

François est MCU depuis septembre 2013 dans l’équipe imagerie ultrasonore. HDR soutenue en décembre 2018. Il est aussi m</font><span style="font-family: Arial, sans-serif; font-size: 13px;">embre du CNU 61.</span></p>

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<p style="text-align: justify; line-height: 1;"><font style="line-height: 1; font-size: 13px;" face="Arial, sans-serif"><b>François Varray</b> a été recruté en 2013 en tant que <b>Maître de

Conférences à l’Université Lyon 1 (département Génie Electrique et Procédés)</b> à CREATIS. Ses travaux de recherche

concernent l’imagerie hybride photoacoustique, l’imagerie ultrasonore médicale ultrarapide

et  3D. Au sein de l’équipe, il joue un rôle

central en faisant le lien entre développements expérimentaux, traitements

associés et transfert vers l’imagerie animale.</font></p>

<p style="text-align: justify; line-height: 1;"><font style="line-height: 1; font-size: 13px;" face="Arial, sans-serif">Après son recrutement, François s’est beaucoup impliqué dans le

<b>montage complet d’une plateforme expérimentale en imagerie photoacoustique.</b> Ce

travail, nécessitant diverses compétences en instrumentation et traitement du

signal temps-réel, a permis de valider plusieurs stratégies de formation

d’images, de conception de sondes ultrasonores, d’imagerie multispectrale et d’imagerie

temps-réel. Ce dernier point s’est appuyé sur la <b>collaboration avec Piero

Tortoli (Université de Florence). </b>En parallèle de ces activités de recherche, François participe et coordonne activement la gestion des codes informatiques produits par l’ensemble des membres (stagiaires, doctorants et permanents) de l’équipe Imagerie Ultrasonore. </font></p>

<p style="text-align: justify; line-height: 1;"><font style="line-height: 1; font-size: 13px;" face="Arial, sans-serif">Depuis ces dernières années, François s’est investi dans

<b>l’imagerie ultrarapide 2D et 3D </b>grâce à l’arrivé d’un nouvel équipement

ultrasonore au laboratoire. Il a ainsi proposé de nouvelles méthodes de

formation d’images appliquées à l’imagerie ultrasonore ou de la cavitation. Ses <b>développements en imageries rapides</b> permettent de intéresser désormais à la vascularisation du

muscle cardiaque et enrichissent la conduite des<b> campagnes multi-modales d'expérimentations animales</b> conduites entre <b>CREATIS</b> et l’unité<b> CARMEN</b> (Equipe du Pr. M. Ovize). Plus récemment, il travaille

sur l’imagerie de l’anisotropie du muscle cardiaque et sa comparaison à

l’imagerie IRM de diffusion.</font></p><p style="text-align: justify; line-height: 1;"><b style="font-size: 13px; font-family: Arial, sans-serif;"><font face="Arial, sans-serif"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fscholar.google.fr%2Fcitations%3Fuser=0dTs158AAAAJ%26hl=fr%26oi=ao/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/M2dhyrdAwqfhdjuwoHNstn8PUHE=96" style="line-height: 1;">Pour savoir plus: ses Publications...</a></font></b></p></div>

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<tr><td valign="top" align="left" class="layout-block-column" width="219"><div class="layout-block-image"><img height="182" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-7.png" border="0" style="display: block;"  class="img-EQMST-2C9B1B88-51B4-46BA-90C1-3B0CCD7BBBA5" width="219"></img><div style="width:0px;height:0px;max-height:0;max-width:0;overflow:hidden;display:none;visibility:hidden;mso-hide:all;"></div></div></td><td rowspan="5" class="layout-block-horizontal-spacer" width="10">  </td><td rowspan="5" valign="top" align="left" class="layout-block-padded-column" width="551"><table cellspacing="0" cellpadding="0">

<tr><td width="551"><v:rect style="width:551px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-70.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" style="padding-left:10px; padding-right:10px; font-size:16px;">

<tr><td><div class="text" style="font-size: 16px; font-family: sans-serif;">

<p style="text-align: justify; line-height: 100%;"><font style="line-height: 100%; font-size: 13px;" face="Arial, sans-serif"><b>François Varray</b> a été recruté en 2013 en tant que <b>Maître de

Conférences à l’Université Lyon 1 (département Génie Electrique et Procédés)</b> à CREATIS. Ses travaux de recherche

concernent l’imagerie hybride photoacoustique, l’imagerie ultrasonore médicale ultrarapide

et  3D. Au sein de l’équipe, il joue un rôle

central en faisant le lien entre développements expérimentaux, traitements

associés et transfert vers l’imagerie animale.</font></p>

<p style="text-align: justify; line-height: 100%;"><font style="line-height: 100%; font-size: 13px;" face="Arial, sans-serif">Après son recrutement, François s’est beaucoup impliqué dans le

<b>montage complet d’une plateforme expérimentale en imagerie photoacoustique.</b> Ce

travail, nécessitant diverses compétences en instrumentation et traitement du

signal temps-réel, a permis de valider plusieurs stratégies de formation

d’images, de conception de sondes ultrasonores, d’imagerie multispectrale et d’imagerie

temps-réel. Ce dernier point s’est appuyé sur la <b>collaboration avec Piero

Tortoli (Université de Florence). </b>En parallèle de ces activités de recherche, François participe et coordonne activement la gestion des codes informatiques produits par l’ensemble des membres (stagiaires, doctorants et permanents) de l’équipe Imagerie Ultrasonore. </font></p>

<p style="text-align: justify; line-height: 100%;"><font style="line-height: 100%; font-size: 13px;" face="Arial, sans-serif">Depuis ces dernières années, François s’est investi dans

<b>l’imagerie ultrarapide 2D et 3D </b>grâce à l’arrivé d’un nouvel équipement

ultrasonore au laboratoire. Il a ainsi proposé de nouvelles méthodes de

formation d’images appliquées à l’imagerie ultrasonore ou de la cavitation. Ses <b>développements en imageries rapides</b> permettent de intéresser désormais à la vascularisation du

muscle cardiaque et enrichissent la conduite des<b> campagnes multi-modales d'expérimentations animales</b> conduites entre <b>CREATIS</b> et l’unité<b> CARMEN</b> (Equipe du Pr. M. Ovize). Plus récemment, il travaille

sur l’imagerie de l’anisotropie du muscle cardiaque et sa comparaison à

l’imagerie IRM de diffusion.</font></p><p style="text-align: justify; line-height: 100%;"><b style="font-size: 13px; font-family: Arial, sans-serif;"><font face="Arial, sans-serif"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fscholar.google.fr%2Fcitations%3Fuser=0dTs158AAAAJ%26hl=fr%26oi=ao/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/Vd9BvGcAoscGn68UIXBfgag_Ma4=96" style="line-height: 100%;">Pour savoir plus: ses Publications...</a></font></b></p></div></td>

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</tr><tr class="layout-block-vertical-spacer" style="height:8px;"><td width="219"><div class="spacer"></div></td>

</tr><tr><td align="left" class="layout-block-column" width="219"><div class="heading" align="left" style="font-size: 16px; font-family: sans-serif;"><b><font face="Arial"> François Varray: Titulaire de l’HDR </font></b></div></td>

</tr><tr class="layout-block-vertical-spacer" style="height:8px;"><td width="219"><div class="spacer"></div></td>

</tr><tr><td width="219" class="layout-block-column"><div class="text" align="left" style="font-size: 16px; font-family: sans-serif;">

<p style="text-align: justify; line-height: 100%;"><font face="Arial, sans-serif" style="line-height: 100%; font-size: 13px;">Arrivé à Creatis en septembre 2008 pour effectuer sa thèse de doctorat,

François est MCU depuis septembre 2013 dans l’équipe imagerie ultrasonore. HDR soutenue en décembre 2018. Il est aussi m</font><span style="font-family: Arial, sans-serif; font-size: 13px;">embre du CNU 61.</span></p>

<p></p>

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                                                                        <td width="760" valign="top" align="left" background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" style="padding-left: 10px; padding-right: 10px;" bgcolor="#ffffff">

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                                                                                                        <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';"><p style="text-align: justify; margin-top: 0px; margin-bottom: 10px; line-height: normal;"><font face="Arial, sans-serif" style="font-style: italic; color: rgb(0, 0, 0); font-size: 13px;">Légende Image ci-dessus: Imagerie photoacoustique multispectrale d’un fantôme d’agar</font></p></div>

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<tr><td width="10" class="layout-block-padding-left">  </td><td width="780" class="layout-block-content-cell" valign="top" align="left"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

<tr><td style="font-size:1px;" width="10">  </td><td align="left" class="layout-block-column" width="760"><div class="text" style="font-size: 16px; font-family: sans-serif;"><p style="text-align: justify; margin-top: 0px; margin-bottom: 10px; line-height: normal;"><font face="Arial, sans-serif" style="font-style: italic; color: #000000; font-size: 13px;">Légende Image ci-dessus: Imagerie photoacoustique multispectrale d’un fantôme d’agar</font></p></div></td><td style="font-size:1px;" width="10">  </td>

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                                                                        <td valign="top" class="layout-block-padded-column" align="center" width="760">

                                                                                <div class="layout-block-image">

                                                                                        <img width="760" height="230" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-9.png" border="0" style="display: block; width: 760px; height: 230px;" class="EQ-58">

                                                                                </div>

                                                                        </td>

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                                                        </tbody></table>

                                                </td>

                                                <td width="10" class="EQ-56"> </td>

                                        </tr>

                                </tbody></table>

                        <!--<![endif]--><!--[if gte mso 9]><div style="display:none;"><table cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" width="800">

<tr><td width="10" class="layout-block-padding-left">  </td><td class="layout-block-content-cell" width="780"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" align="left" style="padding-left:10px; padding-right:10px;" class="layout-block-padded-column">

<tr><td valign="top" class="layout-block-padded-column" align="center"><div class="layout-block-image"><img height="230" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-9.png" border="0" style="display: block;"  class="img-EQMST-9CCDF779-8922-4AA2-B9FA-E8A515783339" width="760"></img><div style="width:0px;height:0px;max-height:0;max-width:0;overflow:hidden;display:none;visibility:hidden;mso-hide:all;"></div></div></td>

</tr></table></div></div></v:textbox></v:rect></td><td width="10" class="layout-block-padding-right">  </td>

</tr></table></div><![endif]--></div>

                        <div width="100%">

                                <!--[if !mso 15]><!--><table width="800" cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" style="mso-hide:all;">

                                        <tbody><tr>

                                                <td width="10" class="EQ-59"> </td>

                                                <td width="780" class="EQ-5B">

                                                        <table cellspacing="0" cellpadding="0" align="left" class="layout-block-column">

                                                                <tbody><tr>

                                                                        <td width="760" valign="top" align="left" background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" style="padding-left: 10px; padding-right: 10px;" bgcolor="#ffffff">

                                                                                <table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

                                                                                        <tbody><tr>

                                                                                                <td align="left" class="layout-block-column" width="760">

                                                                                                        <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';">

<p align="center" style="text-align: justify; line-height: 1;"><font face="Arial, sans-serif" style="font-size: 13px;"><font style="line-height: 1;"><i>Légende Image </i></font><span style="font-style: italic;">ci-dessus:</span><i> Imagerie ultrarapide (a) du

flux en imagerie 2D (imagerie de la microvascularisation du muscle cardiaque)

ou (b) en imagerie 3D (imagerie Doppler de puissance dans un fantome de

vaisseau).</i></font></p>

</div>

                                                                                                </td>

                                                                                        </tr>

                                                                                </tbody></table>

                                                                        </td>

                                                                </tr>

                                                        </tbody></table>

                                                </td>

                                                <td width="10" class="EQ-5A"> </td>

                                        </tr>

                                </tbody></table>

                        <!--<![endif]--><!--[if gte mso 9]><div style="display:none;"><table cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" width="800">

<tr><td width="10" class="layout-block-padding-left">  </td><td width="780" class="layout-block-content-cell" valign="top" align="left"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

<tr><td style="font-size:1px;" width="10">  </td><td align="left" class="layout-block-column" width="760"><div class="text" style="font-size: 16px; font-family: sans-serif;">

<p align="center" style="text-align: justify; line-height: 100%;"><font face="Arial, sans-serif" style="font-size: 13px;"><font style="line-height: 100%;"><i>Légende Image </i></font><span style="font-style: italic;">ci-dessus:</span><i> Imagerie ultrarapide (a) du

flux en imagerie 2D (imagerie de la microvascularisation du muscle cardiaque)

ou (b) en imagerie 3D (imagerie Doppler de puissance dans un fantome de

vaisseau).</i></font></p>

</div></td><td style="font-size:1px;" width="10">  </td>

</tr></table></div></div></v:textbox></v:rect></td><td width="10" class="layout-block-padding-right">  </td>

</tr></table></div><![endif]--></div>

                        <div width="100%">

                                <!--[if !mso 15]><!--><table width="800" cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" style="mso-hide:all;">

                                        <tbody><tr>

                                                <td width="10" class="EQ-5C" style="font-size:1px;"> </td>

                                                <td height="10" background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-70.jpg" class="EQ-5E" bgcolor="#ffffff" width="780">

                                                        <div class="spacer"></div>

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                                                <td width="10" class="EQ-5D" style="font-size:1px;"> </td>

                                        </tr>

                                </tbody></table>

                        <!--<![endif]--><!--[if gte mso 9]><div style="display:none;"><table cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" width="800">

<tr><td width="10" class="layout-block-padding-left" style="font-size:0">  </td><td class="layout-block-content-cell" style="font-size:0;" width="780" height="10"><v:rect style="width:780px;height:10px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-70.jpg" color="#ffffff"></v:fill><div class="spacer"></div></v:rect></td><td width="10" class="layout-block-padding-right" style="font-size:0">  </td>

</tr></table></div><![endif]--></div>

                        <div width="100%">

                                <!--[if !mso 15]><!--><table width="800" cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" style="mso-hide:all;">

                                        <tbody><tr>

                                                <td width="10" class="EQ-60"> </td>

                                                <td class="EQ-62" width="780">

                                                        <table cellspacing="0" cellpadding="0" align="left" class="layout-block-column">

                                                                <tbody><tr>

                                                                        <td width="760" valign="top" align="left" background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" style="padding-left: 10px; padding-right: 10px;" bgcolor="#ffffff">

                                                                                <table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

                                                                                        <tbody><tr>

                                                                                                <td align="left" class="layout-block-column" width="760">

                                                                                                        <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';"><p style="text-align: left; margin: 0px; font-size: 16px; line-height: normal;"><font face="Arial"><b>Simon Lambert:</b></font><b style="font-family: Arial;"> Titulaire de l'HDR</b></p></div>

                                                                                                </td>

                                                                                        </tr>

                                                                                </tbody></table>

                                                                        </td>

                                                                </tr>

                                                        </tbody></table>

                                                </td>

                                                <td width="10" class="EQ-61"> </td>

                                        </tr>

                                </tbody></table>

                        <!--<![endif]--><!--[if gte mso 9]><div style="display:none;"><table cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" width="800">

<tr><td width="10" class="layout-block-padding-left">  </td><td width="780" class="layout-block-content-cell" valign="top" align="left"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

<tr><td style="font-size:1px;" width="10">  </td><td align="left" class="layout-block-column" width="760"><div class="text" style="font-size: 16px; font-family: sans-serif;"><p style="text-align: left; margin: 0px; font-size: 16px; line-height: normal;"><font face="Arial"><b>Simon Lambert:</b></font><b style="font-family: Arial;"> Titulaire de l'HDR</b></p></div></td><td style="font-size:1px;" width="10">  </td>

</tr></table></div></div></v:textbox></v:rect></td><td width="10" class="layout-block-padding-right">  </td>

</tr></table></div><![endif]--></div>

                        <div width="100%">

                                <!--[if !mso 15]><!--><table width="800" cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" style="mso-hide:all;">

                                        <tbody><tr>

                                                <td width="10" class="EQ-63"> </td>

                                                <td width="780" class="EQ-65">

                                                        <table cellspacing="0" cellpadding="0" align="left" class="layout-block-column">

                                                                <tbody><tr>

                                                                        <td width="760" valign="top" align="left" background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" style="padding-left: 10px; padding-right: 10px;" bgcolor="#ffffff">

                                                                                <table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

                                                                                        <tbody><tr>

                                                                                                <td align="left" class="layout-block-column" width="760">

                                                                                                        <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';"><div style="text-align: left;"><span style="font-family: Arial; text-align: justify;"><font style="font-size: 13px;">Après une thèse en instrumentation pour l’IRM qui a permis de mettre au point un capteur IRM supraconducteur, pour l’imagerie du cerveau de souris, avec des qualités d’image pouvant rivaliser avec les très hauts champs (>18 Tesla), ses travaux se sont tournés vers l’élastographie et la diffusion en IRM. Il a conduit la mise au point d'une méthode d’élastographie IRM, sensible à la microstructure des tissus biologiques tels que les vaisseaux sanguins, travaillé à la nouvelle façon de sensibiliser la phase du signal IRM au mouvement brownien par utilisation de gradient de champ quadratique. Depuis son arrivée à <b>CREATIS</b> (Octobre 2015), Simon continue à travailler sur l’élastographie de la microarchitecture tissulaire (<b>Thèse Labex,</b> <b>Mathilde BIGOT</b>) et engage désormais des développements en instrumentation pour l’IRM avec deux projets principaux:  avec un 1er projet visant à utiliser la plastronique et des matériaux innovant pour développer des sondes IRM multifonctions pour l’ingénierie tissulaire  (<b>ESTIMATE, </b></font></span><span style="font-family: Arial; font-size: 13px; text-align: justify;">ANR JCJC</span><span style="font-family: Arial; text-align: justify;"><font style="font-size: 13px;">), et un 2nd projet </font></span><font face="Arial, sans-serif" style="font-size: 13px;">dans lequel il envisage de nouveaux prototypes de sonde double-accord C13-1H et un système d’injection d’agents de contraste hyperpolarisées afin de réaliser des examens IRM</font><font style="font-size: 13px;"><span style="font-family: Arial; text-align: justify;"> (</span><b style="font-family: Arial; text-align: justify;">ERC HP4All, PI: Sami Jannin, ISA)</b><font face="Arial, sans-serif">.</font></font><b style="font-family: Arial; text-align: justify;"><font style="font-size: 13px;">  </font></b></div><div style="text-align: left;"><b style="font-family: Arial; text-align: justify;"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fscholar.google.fr%2Fcitations%3Fuser=jRLbKPsAAAAJ%26hl=fr/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/tSCxjbW08lH9oYTRLnc7XubtIgg=96" style="font-size: 13px;"><b>Pour savoir plus: ses publications...</b></a></b></div></div>

                                                                                                </td>

                                                                                        </tr>

                                                                                </tbody></table>

                                                                        </td>

                                                                </tr>

                                                        </tbody></table>

                                                </td>

                                                <td width="10" class="EQ-64"> </td>

                                        </tr>

                                </tbody></table>

                        <!--<![endif]--><!--[if gte mso 9]><div style="display:none;"><table cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" width="800">

<tr><td width="10" class="layout-block-padding-left">  </td><td width="780" class="layout-block-content-cell" valign="top" align="left"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

<tr><td style="font-size:1px;" width="10">  </td><td align="left" class="layout-block-column" width="760"><div class="text" style="font-size: 16px; font-family: sans-serif;"><div style="text-align: left;"><span style="font-family: Arial; text-align: justify;"><font style="font-size: 13px;">Après une thèse en instrumentation pour l’IRM qui a permis de mettre au point un capteur IRM supraconducteur, pour l’imagerie du cerveau de souris, avec des qualités d’image pouvant rivaliser avec les très hauts champs (>18 Tesla), ses travaux se sont tournés vers l’élastographie et la diffusion en IRM. Il a conduit la mise au point d'une méthode d’élastographie IRM, sensible à la microstructure des tissus biologiques tels que les vaisseaux sanguins, travaillé à la nouvelle façon de sensibiliser la phase du signal IRM au mouvement brownien par utilisation de gradient de champ quadratique. Depuis son arrivée à <b>CREATIS</b> (Octobre 2015), Simon continue à travailler sur l’élastographie de la microarchitecture tissulaire (<b>Thèse Labex,</b> <b>Mathilde BIGOT</b>) et engage désormais des développements en instrumentation pour l’IRM avec deux projets principaux:  avec un 1er projet visant à utiliser la plastronique et des matériaux innovant pour développer des sondes IRM multifonctions pour l’ingénierie tissulaire  (<b>ESTIMATE, </b></font></span><span style="font-family: Arial; font-size: 13px; text-align: justify;">ANR JCJC</span><span style="font-family: Arial; text-align: justify;"><font style="font-size: 13px;">), et un 2nd projet </font></span><font face="Arial, sans-serif" style="font-size: 13px;">dans lequel il envisage de nouveaux prototypes de sonde double-accord C13-1H et un système d’injection d’agents de contraste hyperpolarisées afin de réaliser des examens IRM</font><font style="font-size: 13px;"><span style="font-family: Arial; text-align: justify;"> (</span><b style="font-family: Arial; text-align: justify;">ERC HP4All, PI: Sami Jannin, ISA)</b><font face="Arial, sans-serif">.</font></font><b style="font-family: Arial; text-align: justify;"><font style="font-size: 13px;">  </font></b></div><div style="text-align: left;"><b style="font-family: Arial; text-align: justify;"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fscholar.google.fr%2Fcitations%3Fuser=jRLbKPsAAAAJ%26hl=fr/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/WMtbV3xjqnIsz_xwXCuWc6oARzI=96" style="font-size: 13px;"><b>Pour savoir plus: ses publications...</b></a></b></div></div></td><td style="font-size:1px;" width="10">  </td>

</tr></table></div></div></v:textbox></v:rect></td><td width="10" class="layout-block-padding-right">  </td>

</tr></table></div><![endif]--></div>

                        <div width="100%">

                                <!--[if !mso 15]><!--><table width="800" cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" style="mso-hide:all;">

                                        <tbody><tr>

                                                <td width="10" class="EQ-66"> </td>

                                                <td width="780" background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" class="EQ-68" bgcolor="#ffffff">

                                                        <table cellspacing="0" cellpadding="0" align="left" style="padding-left: 10px; padding-right: 10px;" class="layout-block-box-padding">

                                                                <tbody><tr>

                                                                        <td width="760">

                                                                                <table cellspacing="0" cellpadding="0" align="left" class="layout-block-padded-column" width="191">

                                                                                        <tbody><tr>

                                                                                                <td width="191">

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                                                                                                                <tbody><tr>

                                                                                                                        <td valign="top" align="center" width="191">

                                                                                                                                <div class="layout-block-image">

                                                                                                                                        <img width="191" height="200" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-10.png" border="0" style="display: block; width: 191px; height: 200px;" class="EQ-69">

                                                                                                                                </div>

                                                                                                                        </td>

                                                                                                                </tr>

                                                                                                                <tr class="layout-block-vertical-spacer" style="display:block; height:8px;">

                                                                                                                        <td width="191"><div class="spacer"></div></td>

                                                                                                                </tr>

                                                                                                                <tr>

                                                                                                                        <td valign="top" align="left" width="191">

                                                                                                                                <div  class="text" style="line-height: 18px; font-size: 16px; font-family: 'Lucida Grande';">

<p style="text-align: justify; color: rgb(0, 0, 0); line-height: 1;"><font style="font-style: italic; color: rgb(0, 0, 0); line-height: 1; font-size: 13px;" face="Arial, sans-serif">Capteurs Helmholtz en technologie

plastronique (Collaboration AMPERE Dr. Michel Cabrera)</font></p>

</div>

                                                                                                                        </td>

                                                                                                                </tr>

                                                                                                        </tbody></table>

                                                                                                </td>

                                                                                        </tr>

                                                                                </tbody></table>

                                                                                <table cellspacing="0" cellpadding="0" align="left" class="layout-block-horizontal-spacer" width="10">

                                                                                        <tbody><tr>

                                                                                                <td width="10" class="layout-block-horizontal-spacer" style="line-height:1px;"> </td>

                                                                                        </tr>

                                                                                </tbody></table>

                                                                                <table cellspacing="0" cellpadding="0" align="left" class="layout-block-padded-column" width="259">

                                                                                        <tbody><tr class="layout-block-vertical-spacer" style="display:none; height:0px;">

                                                                                                <td width="259"><div class="spacer"></div></td>

                                                                                        </tr>

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                                                                                                <td width="259">

                                                                                                        <table width="259" cellspacing="0" cellpadding="0" class="layout-block-padded-column">

                                                                                                                <tbody><tr>

                                                                                                                        <td valign="top" align="center" width="259">

                                                                                                                                <div class="layout-block-image">

                                                                                                                                        <img width="259" height="200" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-26.png" border="0" style="display: block; width: 259px; height: 200px;" class="EQ-6A">

                                                                                                                                </div>

                                                                                                                        </td>

                                                                                                                </tr>

                                                                                                                <tr class="layout-block-vertical-spacer" style="display:block; height:8px;">

                                                                                                                        <td width="259"><div class="spacer"></div></td>

                                                                                                                </tr>

                                                                                                                <tr>

                                                                                                                        <td valign="top" align="left" width="259">

                                                                                                                                <div  class="text" style="line-height: 18px; font-size: 16px; font-family: 'Lucida Grande';"><p style="text-align: justify; line-height: 1;"><font face="Arial, sans-serif" style="font-style: italic; color: rgb(0, 0, 0); line-height: 1; font-size: 13px;">Simon Lambert et la Sonde pour l’hyperpolarisation

par « Dynamic Nuclear polarization (Collab. HMRLab Pr. S. Jannin) </font></p>

</div>

                                                                                                                        </td>

                                                                                                                </tr>

                                                                                                        </tbody></table>

                                                                                                </td>

                                                                                        </tr>

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                                                                                        <tbody><tr>

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                                                                                        </tr>

                                                                                </tbody></table>

                                                                                <table cellspacing="0" cellpadding="0" align="left" class="layout-block-padded-column" width="290">

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                                                                                                <td width="290"><div class="spacer"></div></td>

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                                                                                                                                <div class="layout-block-image">

                                                                                                                                        <img width="290" height="200" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-27.png" border="0" style="display: block; width: 290px; height: 200px;" class="EQ-6B">

                                                                                                                                </div>

                                                                                                                        </td>

                                                                                                                </tr>

                                                                                                                <tr class="layout-block-vertical-spacer" style="display:block; height:8px;">

                                                                                                                        <td width="290"><div class="spacer"></div></td>

                                                                                                                </tr>

                                                                                                                <tr>

                                                                                                                        <td valign="top" align="left" width="290">

                                                                                                                                <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';">

<p style="text-align: justify; line-height: 1;"><font face="Arial, sans-serif" style="font-style: italic; color: rgb(0, 0, 0); line-height: 1; font-size: 13px;">Caractérisation d’agrégats

fibrilaires par élastographie IRM (Collab. CRNL Bioran Dr. F. Chauveau)</font></p>

</div>

                                                                                                                        </td>

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                        <!--<![endif]--><!--[if gte mso 9]><div style="display:none;"><table cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" width="800">

<tr><td width="10" class="layout-block-padding-left">  </td><td width="780" class="layout-block-content-cell"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" align="left" class="layout-block-box-padding">

<tr><td rowspan="3" style="font-size:1px;" width="10">  </td><td valign="top" align="center" width="191"><div class="layout-block-image"><img height="200" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-10.png" border="0" style="display: block;"  class="img-EQMST-F25535AD-DC36-4B29-8572-0A392A2CA7DE" width="191"></img><div style="width:0px;height:0px;max-height:0;max-width:0;overflow:hidden;display:none;visibility:hidden;mso-hide:all;"></div></div></td><td class="layout-block-horizontal-spacer" width="10">  </td><td valign="top" align="center" width="259"><div class="layout-block-image"><img height="200" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-26.png" border="0" style="display: block;"  class="img-EQMST-66AE0A92-071F-45D4-BFE3-0CE17ACE1C36" width="259"></img><div style="width:0px;height:0px;max-height:0;max-width:0;overflow:hidden;display:none;visibility:hidden;mso-hide:all;"></div></div></td><td width="10" class="layout-block-horizontal-spacer">  </td><td valign="top" align="center" width="290"><div class="layout-block-image"><img height="200" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-27.png" border="0" style="display: block;"  class="img-EQMST-A342FC23-F520-4BE1-AD4F-998CA5807DE8" width="290"></img><div style="width:0px;height:0px;max-height:0;max-width:0;overflow:hidden;display:none;visibility:hidden;mso-hide:all;"></div></div></td><td rowspan="3" style="font-size:1px;" width="10">  </td>

</tr><tr class="layout-block-vertical-spacer" style="display:block; height:8px;"><td colspan="5"><div class="spacer"></div></td>

</tr><tr><td valign="top" align="left" width="191"><div class="text" style="line-height: 18px; font-size: 16px; font-family: sans-serif;">

<p style="text-align: justify; color: #000000; line-height: 100%;"><font style="font-style: italic; color: #000000; line-height: 100%; font-size: 13px;" face="Arial, sans-serif">Capteurs Helmholtz en technologie

plastronique (Collaboration AMPERE Dr. Michel Cabrera)</font></p>

</div></td><td width="10" class="layout-block-horizontal-spacer">  </td><td valign="top" align="left" width="259"><div class="text" style="line-height: 18px; font-size: 16px; font-family: sans-serif;"><p style="text-align: justify; line-height: 100%;"><font face="Arial, sans-serif" style="font-style: italic; color: #000000; line-height: 100%; font-size: 13px;">Simon Lambert et la Sonde pour l’hyperpolarisation

par « Dynamic Nuclear polarization (Collab. HMRLab Pr. S. Jannin) </font></p>

</div></td><td width="10" class="layout-block-horizontal-spacer">  </td><td valign="top" align="left" width="290"><div class="text" style="font-size: 16px; font-family: sans-serif;">

<p style="text-align: justify; line-height: 100%;"><font face="Arial, sans-serif" style="font-style: italic; color: #000000; line-height: 100%; font-size: 13px;">Caractérisation d’agrégats

fibrilaires par élastographie IRM (Collab. CRNL Bioran Dr. F. Chauveau)</font></p>

</div></td>

</tr></table></div></div></v:textbox></v:rect></td><td width="10" class="layout-block-padding-right">  </td>

</tr></table></div><![endif]--></div>

                        <div width="100%">

                                <!--[if !mso 15]><!--><table width="800" cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" style="mso-hide:all;">

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                                                <td width="10" class="EQ-6C" style="font-size:1px;"> </td>

                                                <td height="10" background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-70.jpg" class="EQ-6E" bgcolor="#ffffff" width="780">

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                                                <td width="10" class="EQ-6D" style="font-size:1px;"> </td>

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                                </tbody></table>

                        <!--<![endif]--><!--[if gte mso 9]><div style="display:none;"><table cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" width="800">

<tr><td width="10" class="layout-block-padding-left" style="font-size:0">  </td><td class="layout-block-content-cell" style="font-size:0;" width="780" height="10"><v:rect style="width:780px;height:10px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-70.jpg" color="#ffffff"></v:fill><div class="spacer"></div></v:rect></td><td width="10" class="layout-block-padding-right" style="font-size:0">  </td>

</tr></table></div><![endif]--></div>

                        <div width="100%">

                                <!--[if !mso 15]><!--><table width="800" cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" style="mso-hide:all;">

                                        <tbody><tr>

                                                <td width="10" class="EQ-70"> </td>

                                                <td class="EQ-72" width="780">

                                                        <table cellspacing="0" cellpadding="0" align="left" class="layout-block-column">

                                                                <tbody><tr>

                                                                        <td width="420" valign="top" align="left" background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-70.jpg" class="layout-block-column" bgcolor="#ffffff">

                                                                                <table cellspacing="0" cellpadding="0" style="padding-left: 10px; padding-right: 10px;" class="layout-block-box-padding">

                                                                                        <tbody><tr>

                                                                                                <td width="400" align="left" class="layout-block-padded-column">

                                                                                                        <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';"><div style="text-align: justify; "><font face="Arial, sans-serif" style="font-size: 13px;">La sténose vasculaire est une réduction du diamètre d’un vaisseau sanguin. La sténose carotidienne est impliquée dans près de 20% des accidents vasculaires cérébraux. Son évaluation clinique se limite actuellement à de simples mesures géométriques et vélocimétriques. Notre objectif est de mettre au point et valider une nouvelle technique non invasive pour mesurer la sévérité de la sténose : la manométrie intravasculaire par écho-Doppler ultrarapide. Cette méthode permettra de mesurer le coefficient de perte de charge lié à sténose, paramètre caractérisant adéquatement l’effet dynamique d’une constriction d’écoulement.<br></font></div><div style="text-align: justify; "><font face="Arial, sans-serif" style="font-size: 13px;"><br></font></div><div><div style="text-align: justify; "><font face="Arial, sans-serif" style="font-size: 13px;">Vascular stenosis is a reduction in the diameter of a blood vessel. Carotid stenosis is involved in nearly 20% of strokes. Its clinical evaluation is currently limited to simple geometric and velocity measurements. Our objective is to develop and validate a new non-invasive technique to measure the severity of stenosis: intravascular manometry by ultrafast Doppler ultrasound. This method will measure the pressure drop coefficient associated with the stenosis, a parameter that adequately characterizes the dynamic effect of a flow constriction.</font></div><br></div></div>

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                                                        <table cellspacing="0" cellpadding="0" align="left" class="layout-block-column">

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                                                                        <td width="350"><div class="spacer"></div></td>

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                                                                <tr>

                                                                        <td width="350" valign="top" align="left" class="layout-block-column">

                                                                                <div class="layout-block-image">

                                                                                        <img width="350" height="230" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-5.png" border="0" style="display: block; width: 350px; height: 230px;" class="EQ-73">

                                                                                </div>

                                                                        </td>

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                                                                        <td width="350"><div class="spacer"></div></td>

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                                                                                <div  class="heading" align="left" style="font-size: 16px; font-family: 'Lucida Grande';">

                                                                                        <font face="Arial"><b>Damien Garcia: Lauréat <font face="Arial"><b><font face="Arial"><b><font face="Arial"><b>Projet Idex <font face="Arial"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fidexlyon.universite-lyon.fr%2Fimpulsion-4948.kjsp/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/wE5PvzVlbgtdY1P4vBZROCB7emQ=96"><b>Impulsion</b></a></font></b></font></b></font></b></font></b></font></div>

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                                                                                <div  class="text" align="left" style="font-size: 16px; font-family: 'Lucida Grande';"><font style="font-size: 13px;" face="Arial, sans-serif"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.youtube.com%2Fwatch%3Fv=7en_nLZxfUw%26ab_channel=UniversiteDeLyon/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/mIax7IjcrTbErMlvplkyieEmFaM=96">Voir la vidéo de Damien expliquant le projet</a>...</font></div>

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                                                <td width="10" class="EQ-71"> </td>

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                        <!--<![endif]--><!--[if gte mso 9]><div style="display:none;"><table cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" width="800">

<tr><td width="10" class="layout-block-padding-left">  </td><td class="layout-block-content-cell" background="box-bg-2.png" width="780"><table width="780" cellspacing="0" cellpadding="0" align="left" class="layout-block-column">

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<tr><td width="420"><v:rect style="width:420px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-70.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" style="padding-left:10px; padding-right:10px; font-size:16px;">

<tr><td><div class="text" style="font-size: 16px; font-family: sans-serif;"><div style="text-align: justify;"><font face="Arial, sans-serif" style="font-size: 13px;">La sténose vasculaire est une réduction du diamètre d’un vaisseau sanguin. La sténose carotidienne est impliquée dans près de 20% des accidents vasculaires cérébraux. Son évaluation clinique se limite actuellement à de simples mesures géométriques et vélocimétriques. Notre objectif est de mettre au point et valider une nouvelle technique non invasive pour mesurer la sévérité de la sténose : la manométrie intravasculaire par écho-Doppler ultrarapide. Cette méthode permettra de mesurer le coefficient de perte de charge lié à sténose, paramètre caractérisant adéquatement l’effet dynamique d’une constriction d’écoulement.<br></font></div><div style="text-align: justify;"><font face="Arial, sans-serif" style="font-size: 13px;"><br></font></div><div><div style="text-align: justify;"><font face="Arial, sans-serif" style="font-size: 13px;">Vascular stenosis is a reduction in the diameter of a blood vessel. Carotid stenosis is involved in nearly 20% of strokes. Its clinical evaluation is currently limited to simple geometric and velocity measurements. Our objective is to develop and validate a new non-invasive technique to measure the severity of stenosis: intravascular manometry by ultrafast Doppler ultrasound. This method will measure the pressure drop coefficient associated with the stenosis, a parameter that adequately characterizes the dynamic effect of a flow constriction.</font></div><br></div></div></td>

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                                                                                        <font face="Arial"><b>Damien Garcia: Lauréat <font face="Arial"><b><font face="Arial"><b><font face="Arial"><b>Projet Idex <font face="Arial"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fidexlyon.universite-lyon.fr%2Fimpulsion-4948.kjsp/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/PjdFTN43Czs5_lPRWTr3If1v4nA=96"><b>Impulsion</b></a></font></b></font></b></font></b></font></b></font></div></td>

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</tr><tr><td width="350" class="layout-block-column"><div class="text" align="left" style="font-size: 16px; font-family: sans-serif;"><font style="font-size: 13px;" face="Arial, sans-serif"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.youtube.com%2Fwatch%3Fv=7en_nLZxfUw%26ab_channel=UniversiteDeLyon/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/y7KNf1VLlBbeDWlc26fr8xF-HUs=96">Voir la vidéo de Damien expliquant le projet</a>...</font></div></td>

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                                                                                                        <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';"><b style="text-align: justify;"><font face="Arial, sans-serif">DERNIERES PUBLICATIONS:</font><i><font face="Open Sans"> </font></i></b></div>

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                                                                                                        <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande'; text-align: justify; color: rgb(0, 0, 0);"><font face="Arial, sans-serif"><b style="font-size: 15px;"><font face="Arial, sans-serif"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fhal.archives-ouvertes.fr%2Fhal-01974104/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/ck-PzYnrei_5h9PbJyYgyHYV6ZQ=96"><b>Repetitive Motion Compensation for Real Time Intraoperative Video Processing.</b></a></font> <span style="text-align: start;">Michaël Sdika, Laure Alston, David Rousseau, Jacques Guyotat, Laurent Mahieu-Williame, Bruno Montcel. </span><i style="text-align: start;">Medical Image Analysis</i><span style="text-align: start;">,  2019, 53, p1-10.</span> </b></font><br style="font-family: Helvetica; font-size: 12px; text-align: start;"><span style="color: rgb(2, 2, 2);"><font face="Arial, sans-serif"><b></b></font></span></div>

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<tr><td style="font-size:1px;" width="10">  </td><td align="left" class="layout-block-column" width="760"><div class="text" style="font-size: 16px; font-family: sans-serif; text-align: justify; color: #000000;"><font face="Arial, sans-serif"><b style="font-size: 15px;"><font face="Arial, sans-serif"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fhal.archives-ouvertes.fr%2Fhal-01974104/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/beuUuasJOVQN0wDeAhkYNXNDUlc=96"><b>Repetitive Motion Compensation for Real Time Intraoperative Video Processing.</b></a></font> <span style="text-align: start;">Michaël Sdika, Laure Alston, David Rousseau, Jacques Guyotat, Laurent Mahieu-Williame, Bruno Montcel. </span><i style="text-align: start;">Medical Image Analysis</i><span style="text-align: start;">,  2019, 53, p1-10.</span> </b></font><br style="font-family: sans-serif; font-size: 12px; text-align: start;"></br><span style="color: #020202;"><font face="Arial, sans-serif"><b></b></font></span></div></td><td style="font-size:1px;" width="10">  </td>

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                                                                                                        <div  class="text" style="text-align: justify; font-size: 16px; font-family: 'Lucida Grande';"><div><font face="Arial, sans-serif" style="font-size: 13px;">In this work, we have proposed an original method of motion compensation on videos for neurosurgery applications. To satisfy the intra-operative constraints our method is: 1 / real time, 2 / robust to occlusions, 3 / robust to wide change of point of view.</font></div><div><font face="Arial, sans-serif" style="font-size: 13px;">From a few seconds of videos during which a third motion estimation method is used, we learn a base of deformation of the surface of the brain (figure below). This base is integrated in an original model of the movement taking into account the deformation of the brain as well as projective transformations of the image due to potential movements of the camera.</font></div><div><font face="Arial, sans-serif" style="font-size: 13px;">The work was done as part of the transversal Omigod project. It is available free of charge until March 2nd here:<span style="text-align: start;"> </span><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fauthors.elsevier.com%2Fa%2F1YNcj4rfPly6sG/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/rY_SbN_LNArZEhWym6EvD3ASqMQ=96" target="_blank" style="text-align: start; color: rgb(0, 115, 152);">https://authors.elsevier.com/a/1YNcj4rfPly6sG</a>. </font></div></div>

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<tr><td width="10" class="layout-block-padding-left">  </td><td width="780" class="layout-block-content-cell" valign="top" align="left"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

<tr><td style="font-size:1px;" width="10">  </td><td align="left" class="layout-block-column" width="760"><div class="text" style="text-align: justify; font-size: 16px; font-family: sans-serif;"><div><font face="Arial, sans-serif" style="font-size: 13px;">In this work, we have proposed an original method of motion compensation on videos for neurosurgery applications. To satisfy the intra-operative constraints our method is: 1 / real time, 2 / robust to occlusions, 3 / robust to wide change of point of view.</font></div><div><font face="Arial, sans-serif" style="font-size: 13px;">From a few seconds of videos during which a third motion estimation method is used, we learn a base of deformation of the surface of the brain (figure below). This base is integrated in an original model of the movement taking into account the deformation of the brain as well as projective transformations of the image due to potential movements of the camera.</font></div><div><font face="Arial, sans-serif" style="font-size: 13px;">The work was done as part of the transversal Omigod project. It is available free of charge until March 2nd here:<span style="text-align: start;"> </span><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fauthors.elsevier.com%2Fa%2F1YNcj4rfPly6sG/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/8itC-1xY0sr8zCT72jas0YAhI1Y=96" target="_blank" style="text-align: start; color: #007398;">https://authors.elsevier.com/a/1YNcj4rfPly6sG</a>. </font></div></div></td><td style="font-size:1px;" width="10">  </td>

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                                                                        <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';"><span style="font-family: Helvetica; font-size: 12px;"><i>Légende Figure: Base d'image du mouvement déformable du cerveau: le déplacement moyen Tμ et les trois premières modes pk. <span title="">.</span> <span title="">La première rangée est pour le déplacement suivant de x,</span> la deuxième rangée correspond au déplacement suivant y.</i></span></div>

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<tr><td width="10" class="layout-block-padding-left">  </td><td width="780" class="layout-block-content-cell"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" align="left" class="layout-block-padded-column">

<tr><td valign="top" class="layout-block-padded-column" align="center" width="567"><div class="layout-block-image"><img height="148" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-25.png" border="0" style="display: block;"  class="img-EQMST-0FBBA8C1-8F5D-4DF7-8D42-8788CF4D9DF4" width="567"></img><div style="width:0px;height:0px;max-height:0;max-width:0;overflow:hidden;display:none;visibility:hidden;mso-hide:all;"></div></div></td><td class="layout-block-horizontal-spacer" width="10">  </td><td width="203" valign="top" align="left" class="layout-block-padded-column"><div class="text" style="font-size: 16px; font-family: sans-serif;"><span style="font-family: sans-serif; font-size: 12px;"><i>Légende Figure: Base d'image du mouvement déformable du cerveau: le déplacement moyen Tμ et les trois premières modes pk. <span title="">.</span> <span title="">La première rangée est pour le déplacement suivant de x,</span> la deuxième rangée correspond au déplacement suivant y.</i></span></div></td>

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<tr><td width="10" class="layout-block-padding-left" style="font-size:0">  </td><td class="layout-block-content-cell" style="font-size:0;" width="780" height="10"><v:rect style="width:780px;height:10px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-70.jpg" color="#ffffff"></v:fill><div class="spacer"></div></v:rect></td><td width="10" class="layout-block-padding-right" style="font-size:0">  </td>

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                                                <td width="10" class="EQ-8D"> </td>

                                                <td valign="top" align="left" background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" class="EQ-8F" bgcolor="#ffffff" width="780">

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                                                                                <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';"><b><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fhal.archives-ouvertes.fr%2Fhal-01956237/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/6KeRqLIv2Lj1FyBbqbe_6O1c764=96" style="font-family: Arial, sans-serif; font-size: 15px; text-align: justify;">Diffeomorphic B-Spline Vector Fields With a Tractable Set of Inequalities.</a><span style="font-family: Arial, sans-serif; font-size: 15px; text-align: justify;"> Michaël Sdika. Mathematics of Computation, American Mathematical Society, In press, 10.1090/mcom/3419</span></b><br><span style="font-family: Helvetica;"><font style="font-size: 13px;"><br></font></span><div><span style="font-family: Helvetica;"><font style="font-size: 13px;"><b><i>Abstract. </i></b>B-spline diffeomorphic vector fields are objects of great interest in image processing and analysis, more specifically for the registration of medical images. In this paper, several conditions on the B-spline coefficients ensuring that a given B-spline vector field is a diffeomorphism are proposed. Some properties of vector fields satisfying these conditions are established showing that they are not too restrictive while having a reasonable computational complexity. This work opens the way to the development of practical image registration algorithms in two and three dimensions whose unknowns would be such diffeomorphic B-spline vector fields.</font></span></div></div>

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                                                                                <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande'; color: rgb(0, 0, 0);"><span style="font-family: Helvetica; font-style: italic;"><font style="font-size: 13px;">Figure Legend: Results of the registration for different methods: the floating image and a grid are mapped through the transformation. A contour image of the fixed image is overlaid on these images.</font></span></div>

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<tr><td width="10" class="layout-block-padding-left">  </td><td valign="top" align="left" class="layout-block-content-cell" width="780"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" align="left" class="layout-block-box-padding">

<tr><td rowspan="3" style="font-size:1px;" width="10">  </td><td rowspan="3" class="layout-block-padded-column" width="355"><div class="text" style="font-size: 16px; font-family: sans-serif;"><b><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fhal.archives-ouvertes.fr%2Fhal-01956237/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/eqWiNrV3C9f8s_FHp7d0hUeiI3o=96" style="font-family: Arial, sans-serif; font-size: 15px; text-align: justify;">Diffeomorphic B-Spline Vector Fields With a Tractable Set of Inequalities.</a><span style="font-family: Arial, sans-serif; font-size: 15px; text-align: justify;"> Michaël Sdika. Mathematics of Computation, American Mathematical Society, In press, 10.1090/mcom/3419</span></b><br><span style="font-family: sans-serif;"><font style="font-size: 13px;"><br></font></span><div><span style="font-family: sans-serif;"><font style="font-size: 13px;"><b><i>Abstract. </i></b>B-spline diffeomorphic vector fields are objects of great interest in image processing and analysis, more specifically for the registration of medical images. In this paper, several conditions on the B-spline coefficients ensuring that a given B-spline vector field is a diffeomorphism are proposed. Some properties of vector fields satisfying these conditions are established showing that they are not too restrictive while having a reasonable computational complexity. This work opens the way to the development of practical image registration algorithms in two and three dimensions whose unknowns would be such diffeomorphic B-spline vector fields.</font></span></div></div></td><td rowspan="3" class="layout-block-horizontal-spacer" width="10">  </td><td class="layout-block-column" width="395"><div class="text" style="font-size: 16px; font-family: sans-serif; color: #000000;"><span style="font-family: sans-serif; font-style: italic;"><font style="font-size: 13px;">Figure Legend: Results of the registration for different methods: the floating image and a grid are mapped through the transformation. A contour image of the fixed image is overlaid on these images.</font></span></div></td><td rowspan="3" style="font-size:1px;" width="10">  </td>

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                                                                                                        <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';"><font face="Arial, sans-serif"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fonlinelibrary.wiley.com%2Fdoi%2Fabs%2F10.1002%2Fejhf.1333/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/NgBmItoFQf4WrP6Rbzst8WJVMSs=96"><b>Machine-learning based phenogrouping in heart failure to identify responders to resynchronization therapy. </b></a></font>Cikes M, Sanchez-Martinez S, Claggett B, <u><b><font face="Arial, sans-serif" style="font-size: 15px;">Duchateau N</font></b></u>, Piella G, Butakoff C, Pouleur AC, Knappe D, Biering-Sørensen T, Kutyifa V, Moss A, Stein K, Solomon SD, Bijnens B. <i><font face="Arial, sans-serif"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.example.org/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/vONRUJ6XTYkbIL56Vslth75NLsU=96"><b><i><font face="Arial, sans-serif"></font></i></b></a><b><i><font face="Arial, sans-serif"><a href="https://Cikes M, Sanchez-Martinez S, Claggett B, Duchateau N, Piella G, Butakoff C, Pouleur AC, Knappe D, Biering-Sørensen T, Kutyifa V, Moss A, Stein K, Solomon SD, Bijnens B."><b><i>European Journal of Heart Failure</i></b></a></font></i></b></font></i>, 2018 (in press). <br></div>

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<tr><td width="10" class="layout-block-padding-left">  </td><td width="780" class="layout-block-content-cell" valign="top" align="left"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

<tr><td style="font-size:1px;" width="10">  </td><td align="left" class="layout-block-column" width="760"><div class="text" style="font-size: 16px; font-family: sans-serif;"><font face="Arial, sans-serif"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fonlinelibrary.wiley.com%2Fdoi%2Fabs%2F10.1002%2Fejhf.1333/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/HP6FGkn7BGL-Z9dXN6aA8lAU2gI=96"><b>Machine-learning based phenogrouping in heart failure to identify responders to resynchronization therapy. </b></a></font>Cikes M, Sanchez-Martinez S, Claggett B, <u><b><font face="Arial, sans-serif" style="font-size: 15px;">Duchateau N</font></b></u>, Piella G, Butakoff C, Pouleur AC, Knappe D, Biering-Sørensen T, Kutyifa V, Moss A, Stein K, Solomon SD, Bijnens B. <i><font face="Arial, sans-serif"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.example.org/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/RXE0mIPM0uLLKZ3OgatTl89ZuVc=96"><b><i><font face="Arial, sans-serif"></font></i></b></a><b><i><font face="Arial, sans-serif"><a href="https://Cikes M, Sanchez-Martinez S, Claggett B, Duchateau N, Piella G, Butakoff C, Pouleur AC, Knappe D, Biering-Sørensen T, Kutyifa V, Moss A, Stein K, Solomon SD, Bijnens B."><b><i>European Journal of Heart Failure</i></b></a></font></i></b></font></i>, 2018 (in press). <br></div></td><td style="font-size:1px;" width="10">  </td>

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<tr><td width="10" class="layout-block-padding-left" style="font-size:0">  </td><td class="layout-block-content-cell" style="font-size:0;" width="780" height="10"><v:rect style="width:780px;height:10px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-70.jpg" color="#ffffff"></v:fill><div class="spacer"></div></v:rect></td><td width="10" class="layout-block-padding-right" style="font-size:0">  </td>

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                                                                        <td width="760" valign="top" align="left" background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" style="padding-left: 10px; padding-right: 10px;" bgcolor="#ffffff">

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                                                                                                        <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande'; text-align: justify; line-height: 1;"><font style="font-size: 13px;" face="Arial, sans-serif">We tested the hypothesis that a machine learning (ML) algorithm utilizing both complex echocardiographic data and clinical parameters could be used to phenogroup a heart failure (HF) cohort and identify patients with beneficial response to cardiac resynchronization therapy (CRT). We studied 1106 HF patients from the Multicenter Automatic Defibrillator Implantation Trial with Cardiac Resynchronization Therapy (MADIT‐CRT) (left ventricular ejection fraction ≤ 30%, QRS ≥ 130 ms, New York Heart Association class ≤ II) randomized to CRT with a defibrillator (CRT‐D, n = 677) or an implantable cardioverter defibrillator (ICD, n = 429). An unsupervised ML algorithm (Multiple Kernel Learning and K‐means clustering) was used to categorize subjects by similarities in clinical parameters, and left ventricular volume and deformation traces at baseline into mutually exclusive groups. The treatment effect of CRT‐D on the primary outcome (all‐cause death or HF event) and on volume response was compared among these groups. Our analysis identified four phenogroups, significantly different in the majority of baseline clinical characteristics, biomarker values, measures of left and right ventricular structure and function and the primary outcome occurrence. Two phenogroups included a higher proportion of known clinical characteristics predictive of CRT response, and were associated with a substantially better treatment effect of CRT‐D on the primary outcome [hazard ratio (HR) 0.35; 95% confidence interval (CI) 0.19–0.64; P = 0.0005 and HR 0.36; 95% CI 0.19–0.68; P = 0.001] than observed in the other groups (interaction P = 0.02). Our results serve as a proof‐of‐concept that, by integrating clinical parameters and full heart cycle imaging data, unsupervised ML can provide a clinically meaningful classification of a phenotypically heterogeneous HF cohort and might aid in optimizing the rate of responders to specific therapies.</font></div>

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<tr><td width="10" class="layout-block-padding-left">  </td><td width="780" class="layout-block-content-cell" valign="top" align="left"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

<tr><td style="font-size:1px;" width="10">  </td><td align="left" class="layout-block-column" width="760"><div class="text" style="font-size: 16px; font-family: sans-serif; text-align: justify; line-height: 100%;"><font style="font-size: 13px;" face="Arial, sans-serif">We tested the hypothesis that a machine learning (ML) algorithm utilizing both complex echocardiographic data and clinical parameters could be used to phenogroup a heart failure (HF) cohort and identify patients with beneficial response to cardiac resynchronization therapy (CRT). We studied 1106 HF patients from the Multicenter Automatic Defibrillator Implantation Trial with Cardiac Resynchronization Therapy (MADIT‐CRT) (left ventricular ejection fraction ≤ 30%, QRS ≥ 130 ms, New York Heart Association class ≤ II) randomized to CRT with a defibrillator (CRT‐D, n = 677) or an implantable cardioverter defibrillator (ICD, n = 429). An unsupervised ML algorithm (Multiple Kernel Learning and K‐means clustering) was used to categorize subjects by similarities in clinical parameters, and left ventricular volume and deformation traces at baseline into mutually exclusive groups. The treatment effect of CRT‐D on the primary outcome (all‐cause death or HF event) and on volume response was compared among these groups. Our analysis identified four phenogroups, significantly different in the majority of baseline clinical characteristics, biomarker values, measures of left and right ventricular structure and function and the primary outcome occurrence. Two phenogroups included a higher proportion of known clinical characteristics predictive of CRT response, and were associated with a substantially better treatment effect of CRT‐D on the primary outcome [hazard ratio (HR) 0.35; 95% confidence interval (CI) 0.19–0.64; P = 0.0005 and HR 0.36; 95% CI 0.19–0.68; P = 0.001] than observed in the other groups (interaction P = 0.02). Our results serve as a proof‐of‐concept that, by integrating clinical parameters and full heart cycle imaging data, unsupervised ML can provide a clinically meaningful classification of a phenotypically heterogeneous HF cohort and might aid in optimizing the rate of responders to specific therapies.</font></div></td><td style="font-size:1px;" width="10">  </td>

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                                                                                                        <div  class="text" style="font-size: 16px; font-style: italic; font-family: 'Lucida Grande'; color: rgb(0, 0, 0); text-align: justify;"><font face="Arial, sans-serif" style="font-size: 13px;"><span style="font-style: italic; color: rgb(0, 0, 0);">Figure legend :</span> Overview of the proposed analysis. Input data consist of both complex descriptors from echocardiography and clinical parameters (left panel), which are used by the unsupervised machine learning algorithm to position subjects according to their similarity through dimensionality reduction, and eventually propose coherent subgroups of subjects using clustering (right panel). 2ch, 2-chamber; 4ch, 4-chamber; ECG, electrocardiogram; MKL, Multiple Kernel Learning.</font></div>

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<tr><td valign="top" class="layout-block-column" align="center"><div class="layout-block-image"><img height="241" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-29.png" border="0" style="display: block;"  class="img-EQMST-AFA02131-8128-45F1-98CB-21BFE149ED33" width="583"></img><div style="width:0px;height:0px;max-height:0;max-width:0;overflow:hidden;display:none;visibility:hidden;mso-hide:all;"></div></div></td><td><div class="spacer"></div></td><td align="left" valign="top" class="layout-block-content-cell" style="padding-left:30px;padding-right:30px;"><div class="text" style="font-size: 16px; font-style: italic; font-family: sans-serif; color: #000000; text-align: justify;"><font face="Arial, sans-serif" style="font-size: 13px;"><span style="font-style: italic; color: #000000;">Figure legend :</span> Overview of the proposed analysis. Input data consist of both complex descriptors from echocardiography and clinical parameters (left panel), which are used by the unsupervised machine learning algorithm to position subjects according to their similarity through dimensionality reduction, and eventually propose coherent subgroups of subjects using clustering (right panel). 2ch, 2-chamber; 4ch, 4-chamber; ECG, electrocardiogram; MKL, Multiple Kernel Learning.</font></div></td>

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</tr></table></div><![endif]--></div>

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                                <!--[if !mso 15]><!--><table width="800" cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" style="mso-hide:all;">

                                        <tbody><tr>

                                                <td width="10" class="EQ-A7"> </td>

                                                <td width="780" class="EQ-A9">

                                                        <table cellspacing="0" cellpadding="0" align="left" class="layout-block-column">

                                                                <tbody><tr>

                                                                        <td width="760" valign="top" align="left" background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" style="padding-left: 10px; padding-right: 10px;" bgcolor="#ffffff">

                                                                                <table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

                                                                                        <tbody><tr>

                                                                                                <td align="left" class="layout-block-column" width="760">

                                                                                                        <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande'; text-align: justify; color: rgb(0, 0, 0); line-height: 1;"><span style="font-size: 15px;"><font face="Arial, sans-serif"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.frontiersin.org%2Farticles%2F10.3389%2Ffnut.2019.00005%2Fabstract/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/UO2W3glBw2mBy3Lhy0RX2MjlgNg=96" style="font-weight: bold; text-align: left;">Chemical-Shift-Encoded MRI and MRS to rev</a><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.frontiersin.org%2Farticles%2F10.3389%2Ffnut.2019.00005%2Fabstract/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/_FdY5xl45tGORrYp2wl6ch3o7a8=96" style="font-weight: bold; text-align: left;">eal immediate and long-term multi-organs composition changes of a 14-days periodic fasting intervention</a><b>. </b><span style="font-weight: bold; color: rgb(2, 2, 2);"><font face="Arial, sans-serif"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.frontiersin.org%2Farticles%2F10.3389%2Ffnut.2019.00005%2Fabstract/3/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/rTXODMQIm1KZgFvTkyIsWnMSFjA=96" style="color: rgb(2, 2, 2); text-decoration: none;">M. Viallon</a></font></span><span style="color: rgb(2, 2, 2);">, <b>B. Leporq, S Drinda, F. Wilhelmi de Toledo, B. Galusca</b><span style="font-weight: 300!important;"> </span><b>, H. Ratiney & </b></span><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Floop.frontiersin.org%2Fpeople%2F402169%2Foverview/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/pRTGWOkZNdG8SjNSXAZJ1hzPW08=96" style="font-weight: bold; color: rgb(2, 2, 2); text-decoration: none; margin-top: 0px; margin-bottom: 0px;">P. Croisille</a>. <span style="font-weight: bold; color: rgb(2, 2, 2);"> </span></font><span style="color: rgb(2, 2, 2);"><font face="Arial, sans-serif"><b><font face="Arial, sans-serif"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.frontiersin.org%2Farticles%2F10.3389%2Ffnut.2019.00005%2Fabstract/4/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/iMmMjtYNI2SlNuo1FatcJVtel-0=96"><b>Front. Nutr. | doi: 10.3389/fnut.2019.00005</b></a></font></b></font></span></span></div>

                                                                                                </td>

                                                                                        </tr>

                                                                                </tbody></table>

                                                                        </td>

                                                                </tr>

                                                        </tbody></table>

                                                </td>

                                                <td width="10" class="EQ-A8"> </td>

                                        </tr>

                                </tbody></table>

                        <!--<![endif]--><!--[if gte mso 9]><div style="display:none;"><table cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" width="800">

<tr><td width="10" class="layout-block-padding-left">  </td><td width="780" class="layout-block-content-cell" valign="top" align="left"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

<tr><td style="font-size:1px;" width="10">  </td><td align="left" class="layout-block-column" width="760"><div class="text" style="font-size: 16px; font-family: sans-serif; text-align: justify; color: #000000; line-height: 100%;"><span style="font-size: 15px;"><font face="Arial, sans-serif"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.frontiersin.org%2Farticles%2F10.3389%2Ffnut.2019.00005%2Fabstract/5/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/L5cXqsweSB67Ik0mK80sITiUWV4=96" style="font-weight: bold; text-align: left;">Chemical-Shift-Encoded MRI and MRS to rev</a><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.frontiersin.org%2Farticles%2F10.3389%2Ffnut.2019.00005%2Fabstract/6/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/hbH1gGKNTWW31FIHg0AvEYhvii0=96" style="font-weight: bold; text-align: left;">eal immediate and long-term multi-organs composition changes of a 14-days periodic fasting intervention</a><b>. </b><span style="font-weight: bold; color: #020202;"><font face="Arial, sans-serif"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.frontiersin.org%2Farticles%2F10.3389%2Ffnut.2019.00005%2Fabstract/7/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/QQWaP6dW-irb3Elx9Wy6M_sQzE0=96" style="color: #020202; text-decoration: none;">M. Viallon</a></font></span><span style="color: #020202;">, <b>B. Leporq, S Drinda, F. Wilhelmi de Toledo, B. Galusca</b><span style="font-weight: 300 !important;"> </span><b>, H. Ratiney & </b></span><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Floop.frontiersin.org%2Fpeople%2F402169%2Foverview/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/-MmTshTm1rd9hqnsranGr6S6mp8=96" style="font-weight: bold; color: #020202; text-decoration: none; margin-top: 0px; margin-bottom: 0px;">P. Croisille</a>. <span style="font-weight: bold; color: #020202;"> </span></font><span style="color: #020202;"><font face="Arial, sans-serif"><b><font face="Arial, sans-serif"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.frontiersin.org%2Farticles%2F10.3389%2Ffnut.2019.00005%2Fabstract/8/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/VT5A-0d2vv0MEWcSD3UoozUqOfc=96"><b>Front. Nutr. | doi: 10.3389/fnut.2019.00005</b></a></font></b></font></span></span></div></td><td style="font-size:1px;" width="10">  </td>

</tr></table></div></div></v:textbox></v:rect></td><td width="10" class="layout-block-padding-right">  </td>

</tr></table></div><![endif]--></div>

                        <div width="100%">

                                <!--[if !mso 15]><!--><table width="800" cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" style="mso-hide:all;">

                                        <tbody><tr>

                                                <td width="10" class="EQ-AA" style="font-size:1px;"> </td>

                                                <td height="10" background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-70.jpg" class="EQ-AC" bgcolor="#ffffff" width="780">

                                                        <div class="spacer"></div>

                                                </td>

                                                <td width="10" class="EQ-AB" style="font-size:1px;"> </td>

                                        </tr>

                                </tbody></table>

                        <!--<![endif]--><!--[if gte mso 9]><div style="display:none;"><table cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" width="800">

<tr><td width="10" class="layout-block-padding-left" style="font-size:0">  </td><td class="layout-block-content-cell" style="font-size:0;" width="780" height="10"><v:rect style="width:780px;height:10px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-70.jpg" color="#ffffff"></v:fill><div class="spacer"></div></v:rect></td><td width="10" class="layout-block-padding-right" style="font-size:0">  </td>

</tr></table></div><![endif]--></div>

                        <div width="100%">

                                <!--[if !mso 15]><!--><table width="800" cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" style="mso-hide:all;">

                                        <tbody><tr>

                                                <td width="10" class="EQ-AE"> </td>

                                                <td width="780" class="EQ-B0">

                                                        <table cellspacing="0" cellpadding="0" align="left" class="layout-block-column">

                                                                <tbody><tr>

                                                                        <td width="760" valign="top" align="left" background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" style="padding-left: 10px; padding-right: 10px;" bgcolor="#ffffff">

                                                                                <table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

                                                                                        <tbody><tr>

                                                                                                <td align="left" class="layout-block-column" width="760">

                                                                                                        <div  class="text" style="text-align: justify; font-size: 16px; font-family: 'Lucida Grande';"><div>

<p style="margin-bottom: 0.0001pt; line-height: 1;"><span lang="EN-US" style="line-height: 1;"><font face="Arial, sans-serif" style="font-size: 13px;">Over much of their evolutionary history,

humans faced more physically demanding and/or precarious living conditions and

were intermittently challenged by food scarcity. Accordingly, cells and organ

systems acquired and retained molecular signaling and metabolic pathways

adapted to these environmental challenges, increasing the functionality and

resilience of individual cells and the entire organism. As a consequence of the

modern hypercaloric or improper diet with a sedentary lifestyle, signaling

pathways that mediate the beneficial effects of the responses to these

historical environmental challenges for health and disease resistance are

disengaged, rendering people vulnerable to obesity, diabetes type 2,

cardiovascular disease, cancers, and neurodegenerative disorders. The reversal

of the epidemic of diseases caused by unchallenging lifestyles will require a

society-wide effort and re-introducing fasting could be a low cost and very

efficient therapy intervention.

Intermittent fasting (IF) diets and periodic Fasting

(PF) are of crucial interest. To

reveal the clinical benefit of such interventions, adequate, robust and ideally

non-invasive biomarkers are needed to quantify the impact of PF objectively,

study and understand the beneficial and/or eventual adverse effects.</font></span></p>

</div><div style="text-align: justify; line-height: 1;"><font face="Arial, sans-serif" style="font-size: 13px;"><span style="text-align: left; line-height: 1;">The aim of this study was to investigate the feasibility of measuring the effects of 14-days low-calory-diet (<200cal) on multi-organs of main interest (liver, visceral/subcutaneous/bone marrow fat, muscle) using non-invasive advanced spectroscopic moreover magnetic resonance imaging (MRI) methods. One subject participated in a 14-day fast under daily supervision of nurses and specialized physicians, ingesting a highly reduced intake: 180 Kcal/day coupled with active walking and at least drinking 3l of water/day. The fasting was preceded by a 7-days pre fasting vegetarian period and followed by 14 days of a stepwise reintroduction of food. The longitudinal study collected imaging and biological data before, at peak fasting, 7 days after re-feeding 1month and 4 months after. Body fat mass in trunk, abdomen, and thigh, liver and muscle mass, were respectively computed using advanced MRI and MRS signal modeling. Fat fraction, MRI relaxivity index T2* and susceptibility (Chi), as well as Fatty acid composition, were calculated at all time points.</span></font></div></div>

                                                                                                </td>

                                                                                        </tr>

                                                                                </tbody></table>

                                                                        </td>

                                                                </tr>

                                                        </tbody></table>

                                                </td>

                                                <td width="10" class="EQ-AF"> </td>

                                        </tr>

                                </tbody></table>

                        <!--<![endif]--><!--[if gte mso 9]><div style="display:none;"><table cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" width="800">

<tr><td width="10" class="layout-block-padding-left">  </td><td width="780" class="layout-block-content-cell" valign="top" align="left"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

<tr><td style="font-size:1px;" width="10">  </td><td align="left" class="layout-block-column" width="760"><div class="text" style="text-align: justify; font-size: 16px; font-family: sans-serif;"><div>

<p style="margin-bottom: 0.0001pt; line-height: 100%;"><span lang="EN-US" style="line-height: 100%;"><font face="Arial, sans-serif" style="font-size: 13px;">Over much of their evolutionary history,

humans faced more physically demanding and/or precarious living conditions and

were intermittently challenged by food scarcity. Accordingly, cells and organ

systems acquired and retained molecular signaling and metabolic pathways

adapted to these environmental challenges, increasing the functionality and

resilience of individual cells and the entire organism. As a consequence of the

modern hypercaloric or improper diet with a sedentary lifestyle, signaling

pathways that mediate the beneficial effects of the responses to these

historical environmental challenges for health and disease resistance are

disengaged, rendering people vulnerable to obesity, diabetes type 2,

cardiovascular disease, cancers, and neurodegenerative disorders. The reversal

of the epidemic of diseases caused by unchallenging lifestyles will require a

society-wide effort and re-introducing fasting could be a low cost and very

efficient therapy intervention.

Intermittent fasting (IF) diets and periodic Fasting

(PF) are of crucial interest. To

reveal the clinical benefit of such interventions, adequate, robust and ideally

non-invasive biomarkers are needed to quantify the impact of PF objectively,

study and understand the beneficial and/or eventual adverse effects.</font></span></p>

</div><div style="text-align: justify; line-height: 100%;"><font face="Arial, sans-serif" style="font-size: 13px;"><span style="text-align: left; line-height: 100%;">The aim of this study was to investigate the feasibility of measuring the effects of 14-days low-calory-diet (<200cal) on multi-organs of main interest (liver, visceral/subcutaneous/bone marrow fat, muscle) using non-invasive advanced spectroscopic moreover magnetic resonance imaging (MRI) methods. One subject participated in a 14-day fast under daily supervision of nurses and specialized physicians, ingesting a highly reduced intake: 180 Kcal/day coupled with active walking and at least drinking 3l of water/day. The fasting was preceded by a 7-days pre fasting vegetarian period and followed by 14 days of a stepwise reintroduction of food. The longitudinal study collected imaging and biological data before, at peak fasting, 7 days after re-feeding 1month and 4 months after. Body fat mass in trunk, abdomen, and thigh, liver and muscle mass, were respectively computed using advanced MRI and MRS signal modeling. Fat fraction, MRI relaxivity index T2* and susceptibility (Chi), as well as Fatty acid composition, were calculated at all time points.</span></font></div></div></td><td style="font-size:1px;" width="10">  </td>

</tr></table></div></div></v:textbox></v:rect></td><td width="10" class="layout-block-padding-right">  </td>

</tr></table></div><![endif]--></div>

                        <div width="100%">

                                <!--[if !mso 15]><!--><table width="800" cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" style="mso-hide:all;">

                                        <tbody><tr>

                                                <td width="10" class="EQ-B1"> </td>

                                                <td background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" class="EQ-B3" bgcolor="#ffffff" width="780">

                                                        <table cellspacing="0" cellpadding="0" align="left" style="padding-left:10px; padding-right:10px;" class="layout-block-padded-column" width="780">

                                                                <tbody><tr>

                                                                        <td valign="top" class="layout-block-padded-column" align="center" width="760">

                                                                                <div class="layout-block-image">

                                                                                        <img width="760" height="530" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-11.png" border="0" style="display: block; width: 760px; height: 530px;" class="EQ-B4">

                                                                                </div>

                                                                        </td>

                                                                </tr>

                                                        </tbody></table>

                                                </td>

                                                <td width="10" class="EQ-B2"> </td>

                                        </tr>

                                </tbody></table>

                        <!--<![endif]--><!--[if gte mso 9]><div style="display:none;"><table cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" width="800">

<tr><td width="10" class="layout-block-padding-left">  </td><td class="layout-block-content-cell" width="780"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" align="left" style="padding-left:10px; padding-right:10px;" class="layout-block-padded-column">

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                                                                                                        <div  class="text" style="text-align: left; font-size: 16px; font-family: 'Lucida Grande'; font-style: italic; line-height: 1;"><font face="Arial, sans-serif" style="font-size: 13px;"><span style="text-align: justify; font-style: italic;"><b>Figure legend: (Left) </b></span><a name="OLE_LINK7" style="text-align: justify;" href="href=" "=""><span lang="EN-US" style="line-height: 150%;">Liver and skeletal muscle post-processing pipeline </span></a><a name="OLE_LINK11" style="text-align: justify;" href="href=" "=""></a><a name="OLE_LINK10" style="text-align: justify;" href="href=" "=""><span lang="EN-US" style="line-height: 150%;">of CSE-MRI based analysis</span></a><span style="text-align: justify;"><span lang="EN-US"> <b>(Right)</b> </span>a) Five

STEAM monovoxel spectra acquired on the liver with the HISTO sequence before

fasting at different TE in order to determine water and lipid T2 and estimate a

PDFF corrected for T2 weighting b)1H MRS liver spectrum acquired with a short

echo time STEAM sequence (here,  on echo

of the HISTO sequence,  TE=24ms, NA=4),

without pre-saturation, before and after fasting c) Quantification of lipid

content for this subject was of   3,3% before

and 3,1% after fasting as estimated with QUEST on STEAM –TE20ms (no T2

correction))  and of  3,1 % vs 2,9 %  for HISTO-PDFF  (with T2 correction) estimation,  showing good consistency with the two

measurements.</span></font>

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<tr><td style="font-size:1px;" width="10">  </td><td align="left" class="layout-block-column" width="760"><div class="text" style="text-align: left; font-size: 16px; font-family: sans-serif; font-style: italic; line-height: 100%;"><font face="Arial, sans-serif" style="font-size: 13px;"><span style="text-align: justify; font-style: italic;"><b>Figure legend: (Left) </b></span><a name="OLE_LINK7" style="text-align: justify;" href="href=" "=""><span lang="EN-US" style="line-height: 150%;">Liver and skeletal muscle post-processing pipeline </span></a><a name="OLE_LINK11" style="text-align: justify;" href="href=" "=""></a><a name="OLE_LINK10" style="text-align: justify;" href="href=" "=""><span lang="EN-US" style="line-height: 150%;">of CSE-MRI based analysis</span></a><span style="text-align: justify;"><span lang="EN-US"> <b>(Right)</b> </span>a) Five

STEAM monovoxel spectra acquired on the liver with the HISTO sequence before

fasting at different TE in order to determine water and lipid T2 and estimate a

PDFF corrected for T2 weighting b)1H MRS liver spectrum acquired with a short

echo time STEAM sequence (here,  on echo

of the HISTO sequence,  TE=24ms, NA=4),

without pre-saturation, before and after fasting c) Quantification of lipid

content for this subject was of   3,3% before

and 3,1% after fasting as estimated with QUEST on STEAM –TE20ms (no T2

correction))  and of  3,1 % vs 2,9 %  for HISTO-PDFF  (with T2 correction) estimation,  showing good consistency with the two

measurements.</span></font>

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                                                                                                        <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande'; text-align: justify; line-height: 1;"><span style="font-size: 15px;"><font face="Arial, sans-serif"><font style="font-weight: bold;"><span style="color: rgb(0, 0, 0); line-height: 1; text-align: start;"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fonlinelibrary.wiley.com%2Fdoi%2Fabs%2F10.1002%2Fjmri.26532/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/KVo8osnX6TyWYeOe0_Cmgo45GP4=96">3D Chemical Shift‐Encoded MRI for Volume and Composition Quantification of Abdominal Adipose Tissue During an Overfeeding Protocol in Healthy Volunteers" </a></span></font><span style="font-weight: bold;">A</span><b>.</b><span style="font-weight: bold;"> Nemeth, B Segrestin, B Leporq, K Seyssel, K Seyssel, K Faraz, V Sauvinet, E Disse, PJ Valette, M Laville, H Ratiney, O Beuf. </span>JMRI 2018. </font></span></div>

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<tr><td style="font-size:1px;" width="10">  </td><td align="left" class="layout-block-column" width="760"><div class="text" style="font-size: 16px; font-family: sans-serif; text-align: justify; line-height: 100%;"><span style="font-size: 15px;"><font face="Arial, sans-serif"><font style="font-weight: bold;"><span style="color: #000000; line-height: 100%; text-align: start;"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fonlinelibrary.wiley.com%2Fdoi%2Fabs%2F10.1002%2Fjmri.26532/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/KgnYYDDTRVISwwHVVp_ldECG0nA=96">3D Chemical Shift‐Encoded MRI for Volume and Composition Quantification of Abdominal Adipose Tissue During an Overfeeding Protocol in Healthy Volunteers" </a></span></font><span style="font-weight: bold;">A</span><b>.</b><span style="font-weight: bold;"> Nemeth, B Segrestin, B Leporq, K Seyssel, K Seyssel, K Faraz, V Sauvinet, E Disse, PJ Valette, M Laville, H Ratiney, O Beuf. </span>JMRI 2018. </font></span></div></td><td style="font-size:1px;" width="10">  </td>

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<p style="margin: 0px; line-height: 1;"><span style="line-height: 1;"><font face="Arial, sans-serif" style="font-size: 13px;">Overweight and obesity are major worldwide health concerns characterized by an abnormal accumulation of fat in adipose tissue (AT) and liver.The prupose of this work was to </font></span><span style="font-family: Arial, sans-serif; font-size: 13px;">evaluate the volume and the fatty acid (FA) composition of the subcutaneous adipose tissue (SAT) and the visceral adipose tissue (VAT) and the fat content in the liver from 3D chemical‐shift‐encoded (CSE)‐MRI acquisition, before and after a 31‐day overfeeding protocol.Twenty‐one nonobese healthy male volunteers were included. </span></p><p style="margin: 0px; line-height: 1;"><span style="line-height: 1;"><font face="Arial, sans-serif" style="font-size: 13px;">A 3D spoiled‐gradient multiple echo sequence and STEAM sequence were performed at 3T.  </font></span><span style="font-family: Arial, sans-serif; font-size: 13px;">AT volume was automatically segmented on CSE‐MRI between L2 to L4 lumbar vertebrae and compared to the dual‐energy X‐ray absorptiometry (DEXA) measurement. CSE‐MRI and MR spectroscopy (MRS) data were analyzed to assess the proton density fat fraction (PDFF) in the liver and the FA composition in SAT and VAT. Gas chromatography‐mass spectrometry (GC‐MS) analyses were performed on 13 SAT samples as a FA composition countermeasure. We have shown that SAT and VAT volumes were significantly increased (P < 0.001). CSE‐MRI and DEXA measurements were strongly correlated (r = 0.98, P < 0.001). PDFF significantly increased in the liver (+1.35, P = 0.002 for CSE‐MRI, + 1.74, P = 0.002 for MRS). FA composition of SAT and VAT appeared to be consistent between localized‐MRS and CSE‐MRI (on whole segmented volume) measurements. A significant difference between SAT and VAT FA composition was found (P < 0.001 for CSE‐MRI, P = 0.001 for MRS). MRS and CSE‐MRI measurements of the FA composition were correlated with the GC‐MS results (for ndb: rMRS/GC‐MS = 0.83 P < 0.001, rCSE‐MRI/GC‐MS = 0.84, P = 0.001; for nmidb: rMRS/GC‐MS = 0.74, P = 0.006, rCSE‐MRI/GC‐MS = 0.66, P = 0.020).The follow‐up of liver PDFF, volume, and FA composition of AT during an overfeeding diet was demonstrated through different methods. The CSE‐MRI sequence associated with a dedicated postprocessing was found reliable for such quantification.</span></p></div>

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<p style="margin: 0px; line-height: 100%;"><span style="line-height: 100%;"><font face="Arial, sans-serif" style="font-size: 13px;">Overweight and obesity are major worldwide health concerns characterized by an abnormal accumulation of fat in adipose tissue (AT) and liver.The prupose of this work was to </font></span><span style="font-family: Arial, sans-serif; font-size: 13px;">evaluate the volume and the fatty acid (FA) composition of the subcutaneous adipose tissue (SAT) and the visceral adipose tissue (VAT) and the fat content in the liver from 3D chemical‐shift‐encoded (CSE)‐MRI acquisition, before and after a 31‐day overfeeding protocol.Twenty‐one nonobese healthy male volunteers were included. </span></p><p style="margin: 0px; line-height: 100%;"><span style="line-height: 100%;"><font face="Arial, sans-serif" style="font-size: 13px;">A 3D spoiled‐gradient multiple echo sequence and STEAM sequence were performed at 3T.  </font></span><span style="font-family: Arial, sans-serif; font-size: 13px;">AT volume was automatically segmented on CSE‐MRI between L2 to L4 lumbar vertebrae and compared to the dual‐energy X‐ray absorptiometry (DEXA) measurement. CSE‐MRI and MR spectroscopy (MRS) data were analyzed to assess the proton density fat fraction (PDFF) in the liver and the FA composition in SAT and VAT. Gas chromatography‐mass spectrometry (GC‐MS) analyses were performed on 13 SAT samples as a FA composition countermeasure. We have shown that SAT and VAT volumes were significantly increased (P < 0.001). CSE‐MRI and DEXA measurements were strongly correlated (r = 0.98, P < 0.001). PDFF significantly increased in the liver (+1.35, P = 0.002 for CSE‐MRI, + 1.74, P = 0.002 for MRS). FA composition of SAT and VAT appeared to be consistent between localized‐MRS and CSE‐MRI (on whole segmented volume) measurements. A significant difference between SAT and VAT FA composition was found (P < 0.001 for CSE‐MRI, P = 0.001 for MRS). MRS and CSE‐MRI measurements of the FA composition were correlated with the GC‐MS results (for ndb: rMRS/GC‐MS = 0.83 P < 0.001, rCSE‐MRI/GC‐MS = 0.84, P = 0.001; for nmidb: rMRS/GC‐MS = 0.74, P = 0.006, rCSE‐MRI/GC‐MS = 0.66, P = 0.020).The follow‐up of liver PDFF, volume, and FA composition of AT during an overfeeding diet was demonstrated through different methods. The CSE‐MRI sequence associated with a dedicated postprocessing was found reliable for such quantification.</span></p></div></td><td style="font-size:1px;" width="10">  </td>

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                                                                                                        <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';"><i style="font-family: Arial, sans-serif;"><font style="font-size: 13px;">Figure Legend: A STEAM sequence was acquired in liver, subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) using the following parameters:  TR = 3000 ms, TE= 14 ms, TM= 10 ms, VOI of 20×20×20 mm3, no water suppression, 2048 Hz bandwidth, 1024 data points, 4 signal averages for VAT and SAT and 32 signal averages for the liver. For SAT and VAT, further acquisitions were made with TE = [24, 34, 44, 54, 64] ms</font></i></div>

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<tr><td width="10" class="layout-block-padding-left">  </td><td width="780" class="layout-block-content-cell" valign="top" align="left"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

<tr><td style="font-size:1px;" width="10">  </td><td align="left" class="layout-block-column" width="760"><div class="text" style="font-size: 16px; font-family: sans-serif;"><i style="font-family: Arial, sans-serif;"><font style="font-size: 13px;">Figure Legend: A STEAM sequence was acquired in liver, subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) using the following parameters:  TR = 3000 ms, TE= 14 ms, TM= 10 ms, VOI of 20×20×20 mm3, no water suppression, 2048 Hz bandwidth, 1024 data points, 4 signal averages for VAT and SAT and 32 signal averages for the liver. For SAT and VAT, further acquisitions were made with TE = [24, 34, 44, 54, 64] ms</font></i></div></td><td style="font-size:1px;" width="10">  </td>

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                                                                                                        <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande'; text-align: justify;"><font face="Arial, sans-serif" style="font-size: 15px;"><span style="text-align: start;"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.sciencedirect.com%2Fscience%2Farticle%2Fpii%2FS0160289618300898%3Fvia%253Dihub/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/lyjoP8uyS7ZTANnUwQQmaVrK-Ek=96" style="font-weight: bold; color: rgb(8, 28, 255);">Brain structural connectivity correlates with fluid intelligence in children: A DTI graph analysis. </a><b>G Kocevar, I Suprano, C Stamile, S Hannoun, P Fourneret, O Revol, F Nusbaum, D Sappey-Marinier.</b> </span><font color="#000000"><a title="Go to Intelligence on ScienceDirect" href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.sciencedirect.com%2Fscience%2Fjournal%2F01602896/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/03BwiwjhewxKfGn9RZE6UZNlFKI=96" style="text-align: center; margin-top: 0px; margin-bottom: 0px; text-decoration: none; color: rgb(0, 16, 255);">Intelligence</a>. <a title="Go to table of contents for this volume/issue" href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.sciencedirect.com%2Fscience%2Fjournal%2F01602896%2F72%2Fsupp%2FC/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/1fX0n-APtm3lmvO6WugE-7_P8lw=96" style="text-align: center; margin-top: 0px; margin-bottom: 0px; text-decoration: none; color: rgb(0, 16, 255);">Volume 72</a><span style="text-align: center;">, January–February 2019, Pages 67-75</span></font></font></div>

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<tr><td style="font-size:1px;" width="10">  </td><td align="left" class="layout-block-column" width="760"><div class="text" style="font-size: 16px; font-family: sans-serif; text-align: justify;"><font face="Arial, sans-serif" style="font-size: 15px;"><span style="text-align: start;"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.sciencedirect.com%2Fscience%2Farticle%2Fpii%2FS0160289618300898%3Fvia%253Dihub/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/nT0PnwfN5QLbJbei8-iZJwUI7R4=96" style="font-weight: bold; color: #081CFF;">Brain structural connectivity correlates with fluid intelligence in children: A DTI graph analysis. </a><b>G Kocevar, I Suprano, C Stamile, S Hannoun, P Fourneret, O Revol, F Nusbaum, D Sappey-Marinier.</b> </span><font color="#000000"><a title="Go to Intelligence on ScienceDirect" href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.sciencedirect.com%2Fscience%2Fjournal%2F01602896/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/zckoFDzPCD6vIjyUvCHi7t3rBLU=96" style="text-align: center; margin-top: 0px; margin-bottom: 0px; text-decoration: none; color: #0010FF;">Intelligence</a>. <a title="Go to table of contents for this volume/issue" href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.sciencedirect.com%2Fscience%2Fjournal%2F01602896%2F72%2Fsupp%2FC/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/yNbNOEHhas9lEI1Z3Dsghz17DJo=96" style="text-align: center; margin-top: 0px; margin-bottom: 0px; text-decoration: none; color: #0010FF;">Volume 72</a><span style="text-align: center;">, January–February 2019, Pages 67-75</span></font></font></div></td><td style="font-size:1px;" width="10">  </td>

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<tr><td width="10" class="layout-block-padding-left" style="font-size:0">  </td><td class="layout-block-content-cell" style="font-size:0;" width="780" height="10"><v:rect style="width:780px;height:10px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-70.jpg" color="#ffffff"></v:fill><div class="spacer"></div></v:rect></td><td width="10" class="layout-block-padding-right" style="font-size:0">  </td>

</tr></table></div><![endif]--></div>

                        <div width="100%">

                                <!--[if !mso 15]><!--><table width="800" cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" style="mso-hide:all;">

                                        <tbody><tr>

                                                <td width="10" class="EQ-D8"> </td>

                                                <td width="780" class="EQ-DA">

                                                        <table cellspacing="0" cellpadding="0" align="left" class="layout-block-column">

                                                                <tbody><tr>

                                                                        <td width="760" valign="top" align="left" background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" style="padding-left: 10px; padding-right: 10px;" bgcolor="#ffffff">

                                                                                <table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

                                                                                        <tbody><tr>

                                                                                                <td align="left" class="layout-block-column" width="760">

                                                                                                        <div  class="text" style="text-align: justify; font-size: 16px; font-family: 'Lucida Grande';"><font face="Arial, sans-serif" style="font-size: 13px;"><span style="text-align: left;">The aim of this study was to investigate the feasibility of measuring the effects of 14-days low-calory-diet (<200cal) on multi-organs of main interest (liver, visceral/subcutaneous/bone marrow fat, muscle) using non-invasive advanced spectroscopic moreover magnetic resonance imaging (MRI) methods. One subject participated in a 14-day fast under daily supervision of nurses and specialized physicians, ingesting a highly reduced intake: 180 Kcal/day coupled with active walking and at least drinking 3l of water/day. The fasting was preceded by a 7-days pre fasting vegetarian period and followed by 14 days of a stepwise reintroduction of food. The longitudinal study collected imaging and biological data before, at peak fasting, 7 days after re-feeding 1month and 4 months after. Body fat mass in trunk, abdomen, and thigh, liver and muscle mass, were respectively computed using advanced MRI and MRS signal modeling. Fat fraction, MRI relaxivity index T2* and susceptibility (Chi), as well as Fatty acid composition, were calculated at all time points.</span></font></div>

                                                                                                </td>

                                                                                        </tr>

                                                                                </tbody></table>

                                                                        </td>

                                                                </tr>

                                                        </tbody></table>

                                                </td>

                                                <td width="10" class="EQ-D9"> </td>

                                        </tr>

                                </tbody></table>

                        <!--<![endif]--><!--[if gte mso 9]><div style="display:none;"><table cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" width="800">

<tr><td width="10" class="layout-block-padding-left">  </td><td width="780" class="layout-block-content-cell" valign="top" align="left"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

<tr><td style="font-size:1px;" width="10">  </td><td align="left" class="layout-block-column" width="760"><div class="text" style="text-align: justify; font-size: 16px; font-family: sans-serif;"><font face="Arial, sans-serif" style="font-size: 13px;"><span style="text-align: left;">The aim of this study was to investigate the feasibility of measuring the effects of 14-days low-calory-diet (<200cal) on multi-organs of main interest (liver, visceral/subcutaneous/bone marrow fat, muscle) using non-invasive advanced spectroscopic moreover magnetic resonance imaging (MRI) methods. One subject participated in a 14-day fast under daily supervision of nurses and specialized physicians, ingesting a highly reduced intake: 180 Kcal/day coupled with active walking and at least drinking 3l of water/day. The fasting was preceded by a 7-days pre fasting vegetarian period and followed by 14 days of a stepwise reintroduction of food. The longitudinal study collected imaging and biological data before, at peak fasting, 7 days after re-feeding 1month and 4 months after. Body fat mass in trunk, abdomen, and thigh, liver and muscle mass, were respectively computed using advanced MRI and MRS signal modeling. Fat fraction, MRI relaxivity index T2* and susceptibility (Chi), as well as Fatty acid composition, were calculated at all time points.</span></font></div></td><td style="font-size:1px;" width="10">  </td>

</tr></table></div></div></v:textbox></v:rect></td><td width="10" class="layout-block-padding-right">  </td>

</tr></table></div><![endif]--></div>

                        <div width="100%" class="desktop-only">

                                <!--[if !mso 15]><!--><table width="800" cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" style="mso-hide:all;">

                                        <tbody><tr>

                                                <td width="10"> </td>

                                                <td background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" bgcolor="#ffffff" width="780">

                                                        <table cellspacing="0" cellpadding="0" align="left" style="padding-left:10px; padding-right:10px;" class="layout-block-padded-column" width="780">

                                                                <tbody><tr>

                                                                        <td valign="top" class="layout-block-padded-column" align="center" width="760">

                                                                                <div class="layout-block-image">

                                                                                        <img width="760" height="318" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-12.png" border="0" style="line-height: 1px; display: block; width: 760px; height: 318px;">

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                                                                        </td>

                                                                </tr>

                                                        </tbody></table>

                                                </td>

                                                <td width="10"> </td>

                                        </tr>

                                </tbody></table>

                        <!--<![endif]--><!--[if gte mso 9]><div style="display:none;"><table cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" width="800">

<tr><td width="10" class="layout-block-padding-left">  </td><td class="layout-block-content-cell" width="780"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" align="left" style="padding-left:10px; padding-right:10px;" class="layout-block-padded-column">

<tr><td valign="top" class="layout-block-padded-column" align="center"><div class="layout-block-image"><img height="318" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-12.png" border="0" style="line-height: 1px; display: block;" class="img-EQMST-6A1C241E-922F-4B77-BB60-338B191B4565" width="760"></img><div style="width:0px;height:0px;max-height:0;max-width:0;overflow:hidden;display:none;visibility:hidden;mso-hide:all;"></div></div></td>

</tr></table></div></div></v:textbox></v:rect></td><td width="10" class="layout-block-padding-right">  </td>

</tr></table></div><![endif]--></div>

                        <!--[if !mso ]><!-->

                        <div width="100%" class="mobile-only hide" style="display: none; max-height: 0px; overflow: hidden;">

                                <table width="375" cellspacing="0" cellpadding="0" class="layout-block-wrapping-table hide" style="display: none; max-height: 0px; overflow: hidden;">

                                        <tbody><tr>

                                                <td width="10"> </td>

                                                <td background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" bgcolor="#ffffff" width="355">

                                                        <table cellspacing="0" cellpadding="0" align="left" style="padding-left: 10px; padding-right: 10px; display: none; max-height: 0px; overflow: hidden;" class="layout-block-padded-column hide" width="355">

                                                                <tbody><tr>

                                                                        <td valign="top" class="layout-block-padded-column" align="center" width="335">

                                                                                <div class="layout-block-image hide" style="display: none; max-height: 0px; overflow: hidden;">

                                                                                        <img width="335" height="140" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-32.png" border="0" style="line-height: 1px; display: none; max-height: 0px; overflow: hidden; width: 335px; height: 140px;" class="hide">

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                                                <td width="10"> </td>

                                        </tr>

                                </tbody></table>

                        </div><!--<![endif]-->

                        <div width="100%">

                                <!--[if !mso 15]><!--><table width="800" cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" style="mso-hide:all;">

                                        <tbody><tr>

                                                <td width="10" class="EQ-DB"> </td>

                                                <td width="780" class="EQ-DD">

                                                        <table cellspacing="0" cellpadding="0" align="left" class="layout-block-column">

                                                                <tbody><tr>

                                                                        <td width="760" valign="top" align="left" background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" style="padding-left: 10px; padding-right: 10px;" bgcolor="#ffffff">

                                                                                <table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

                                                                                        <tbody><tr>

                                                                                                <td align="left" class="layout-block-column" width="760">

                                                                                                        <div  class="text" style="text-align: left; font-size: 16px; font-family: 'Lucida Grande'; font-style: italic; line-height: 1;"><font style="font-size: 13px;"><span style="font-family: Helvetica; text-align: justify; font-style: italic;"><b style="font-family: Helvetica;">Figure legend: (Left) </b></span></font><span style="font-family: Arial, Helvetica, "Lucida Sans Unicode", "Microsoft Sans Serif", "Segoe UI Symbol", STIXGeneral, "Cambria Math", "Arial Unicode MS", sans-serif; font-size: 13px;">Overview of the pipeline used for data processing (top) & </span><font style="font-size: 13px;"><span style="font-family: Arial, Helvetica, "Lucida Sans Unicode", "Microsoft Sans Serif", "Segoe UI Symbol", STIXGeneral, "Cambria Math", "Arial Unicode MS", sans-serif; font-style: normal;">Correlations between PA1-g intelligence domain and local graph metrics in the right (bottom).</span><b style="text-align: justify;"><span lang="EN-US" style="font-family: Arial, sans-serif; font-weight: normal;"> </span><span lang="EN-US" style="font-family: Arial, sans-serif;">(Right)</span><span lang="EN-US" style="font-family: Arial, sans-serif; font-weight: normal;"> </span></b></font><span style="font-family: Arial, Helvetica, "Lucida Sans Unicode", "Microsoft Sans Serif", "Segoe UI Symbol", STIXGeneral, "Cambria Math", "Arial Unicode MS", sans-serif; font-size: 13px;">Schematic representation of the connectivity matrix subdivision in different networks, including left-, right-, and inter- hemispheres networks & lobes networks. The cortical regions in each lobe are also reported.</span>

</div>

                                                                                                </td>

                                                                                        </tr>

                                                                                </tbody></table>

                                                                        </td>

                                                                </tr>

                                                        </tbody></table>

                                                </td>

                                                <td width="10" class="EQ-DC"> </td>

                                        </tr>

                                </tbody></table>

                        <!--<![endif]--><!--[if gte mso 9]><div style="display:none;"><table cellspacing="0" cellpadding="0" class="layout-block-wrapping-table" width="800">

<tr><td width="10" class="layout-block-padding-left">  </td><td width="780" class="layout-block-content-cell" valign="top" align="left"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

<tr><td style="font-size:1px;" width="10">  </td><td align="left" class="layout-block-column" width="760"><div class="text" style="text-align: left; font-size: 16px; font-family: sans-serif; font-style: italic; line-height: 100%;"><font style="font-size: 13px;"><span style="font-family: sans-serif; text-align: justify; font-style: italic;"><b style="font-family: sans-serif;">Figure legend: (Left) </b></span></font><span style="font-family: Arial, sans-serif; font-size: 13px;">Overview of the pipeline used for data processing (top) & </span><font style="font-size: 13px;"><span style="font-family: Arial, sans-serif; font-style: normal;">Correlations between PA1-g intelligence domain and local graph metrics in the right (bottom).</span><b style="text-align: justify;"><span lang="EN-US" style="font-family: Arial, sans-serif; font-weight: normal;"> </span><span lang="EN-US" style="font-family: Arial, sans-serif;">(Right)</span><span lang="EN-US" style="font-family: Arial, sans-serif; font-weight: normal;"> </span></b></font><span style="font-family: Arial, sans-serif; font-size: 13px;">Schematic representation of the connectivity matrix subdivision in different networks, including left-, right-, and inter- hemispheres networks & lobes networks. The cortical regions in each lobe are also reported.</span>

</div></td><td style="font-size:1px;" width="10">  </td>

</tr></table></div></div></v:textbox></v:rect></td><td width="10" class="layout-block-padding-right">  </td>

</tr></table></div><![endif]--></div>

                        <!--[if !mso ]><!-->

                        <div width="100%" class="mobile-only hide" style="display: none; max-height: 0px; overflow: hidden;">

                                <table width="375" cellspacing="0" cellpadding="0" class="layout-block-wrapping-table hide" style="display: none; max-height: 0px; overflow: hidden;">

                                        <tbody><tr>

                                                <td width="10"> </td>

                                                <td background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" bgcolor="#ffffff" width="355">

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                                                                <tbody><tr>

                                                                        <td valign="top" class="layout-block-padded-column" align="center" width="335">

                                                                                <div class="layout-block-image hide" style="display: none; max-height: 0px; overflow: hidden;">

                                                                                        <img width="335" height="124" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-33.png" border="0" style="line-height: 1px; display: none; max-height: 0px; overflow: hidden; width: 335px; height: 124px;" class="hide">

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                                        </tr>

                                </tbody></table>

                        </div><!--<![endif]-->

                        <!--[if !mso ]><!-->

                        <div width="100%" class="mobile-only hide" style="display: none; max-height: 0px; overflow: hidden;">

                                <table width="375" cellspacing="0" cellpadding="0" class="layout-block-wrapping-table hide" style="display: none; max-height: 0px; overflow: hidden;">

                                <tbody><tr>

                                        <td width="10"> </td>

                                        <td width="355" background="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" bgcolor="#ffffff">

                                                <table cellspacing="0" cellpadding="0" align="left" class="layout-block-padded-column hide" width="355" style="display: none; max-height: 0px; overflow: hidden;">

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                                                                <td width="355" valign="top" class="layout-block-padded-column" align="center">

                                                                        <div class="layout-block-image hide" style="display: none; max-height: 0px; overflow: hidden;">

                                                                                <img width="355" height="337" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-34.png" border="0" style="line-height: 1px; display: none; max-height: 0px; overflow: hidden; width: 355px; height: 337px;" class="hide">

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                                                                        <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';"><div style="text-align: justify;"><span style="caret-color: rgb(0, 0, 0); font-family: Arial, sans-serif; font-size: 13px;">In this paper, a nonlinear beamformer (image reconstruction algorithm) is applied to plane wave imaging (high frame rate technique) to improve the resolution and contrast of ultrasound images. This technique uses the pth-root of signals to increase the effects of coherent summation involved in the conventional beamforming algorithm (Delay-And-Sum, DAS). The proposed method is referred to as p-DAS, and it has been tested here on numerical and experimental data from the open access platform of the Plane wave Imaging Challenge in Medical UltraSound (PICMUS). This study demonstrates that p-DAS achieves better resolution and artifact rejection than the conventional. However, it tends to distort the conventional speckle structure. Moreover, it is demonstrated that p-DAS, for p = 2, is very similar to the nonlinear filtered-delay-multiply-and-sum (FDMAS) beamforming, but also that its impact on image quality can be tuned hanging the value of p.</span></div><div style="text-align: justify;"><span style="caret-color: rgb(0, 0, 0); font-family: Arial, sans-serif; font-size: 13px;"><br></span></div><div style="text-align: justify;"><font face="Arial, sans-serif" style="font-size: 13px;"><i style="caret-color: rgb(0, 0, 0);"><b>Figure legend:</b> </i><font color="#222222"><span style="caret-color: rgb(34, 34, 34); letter-spacing: 0.17000000178813934px;"><i>B-mode images (with single plane wave imaging) with four different beamformers: DAS, FDMAS, 2-DAS, and 3-DAS. On numerical phantoms (a–d) for the resolution and (e–h) for the contrast. On experimental phantoms (i–l) for the resolution and (m–p) for the contrast. </i></span></font></font></div></div>

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                                                                        <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';"><div style="text-align: justify; font-size: 13px; font-style: italic; font-family: Arial, sans-serif; color: rgb(0, 0, 0);">Figure Legend: Demonstration of video magnification applied to medical ultrasound imaging for one example with ultrasound (carotid). Close-up views of the distal wall are presented over time at 800, 832 and 864 ms after the beginning of acquisition. Upper row (a) is the original US images and the lower row (b) is the magnified data. Radial motion, due to the propagation of a pulse wave, is only visible on the magnified data (b).</div><div><br></div></div>

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                                                                                                        <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';"><b><font face="Arial, sans-serif">FLASH THESE: </font></b><span style="font-size: 15px;"><font face="Arial, sans-serif" style="font-size: 16px; font-weight: bold; font-family: Arial, sans-serif; color: rgb(0, 0, 0);">Connectivité cérébrale : un marqueur IRM local et global pour mieux caractériser le substrat neural de "l’Intelligence"</font></span><br style="font-family: Helvetica; font-size: 12px;"></div>

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<tr><td style="font-size:1px;">  </td><td width="760" valign="top" align="left"><div class="heading" style="font-size: 16px; font-family: sans-serif;"><b><font face="Arial, sans-serif">FLASH THESE: </font></b><span style="font-size: 15px;"><font face="Arial, sans-serif" style="font-size: 16px; font-weight: bold; font-family: Arial, sans-serif; color: #000000;">Connectivité cérébrale : un marqueur IRM local et global pour mieux caractériser le substrat neural de "l’Intelligence"</font></span><br style="font-family: sans-serif; font-size: 12px;"></br></div></td><td style="font-size:1px;">  </td>

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                                                                                        <font face="Arial"><b style="font-size: 23px;">Ilaria Suprano</b></font></div>

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                                                                                <div  class="text" align="left" style="font-size: 16px; font-family: 'Lucida Grande';"><div style="text-align: left;"><font face="Arial, sans-serif" style="font-size: 13px;">Diplômée d’un master en Physique de l’Université Sapienza de Rome, Ilaria est actuellement en 3e année de thèse dans l’équipe « RMN et optique : de la mesure au biomarqueur ». </font><span style="font-family: Arial, sans-serif; text-align: justify;"><font style="font-size: 13px;">Ses travaux portent sur le développement de l’IRM fonctionnelle pour </font><b><font style="font-size: 13px;">la caractérisation du s</font><span style="font-size: 12px;">ubstrat neural de « l’intelligence » </span></b><span style="font-size: 12px;">via des mesures de connectivité cérébrale. </span></span><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fscholar.google.fr%2Fcitations%3Fuser=AzVWddwAAAAJ%26hl=fr/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/SUOSWcd04wlT-82CCgcdcXM7v4I=96"><font face="Arial, sans-serif" style="font-size: 13px;">En savoir plus sur Ilaria…</font></a></div><div style="text-align: left;"><br></div></div>

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<p style="text-align: justify; line-height: 1;"><span style="font-family: Arial, sans-serif; line-height: 1;"><font style="font-size: 13px;">Les <b>personnes à Haut

Potentiel (HP, QI > 130)</b> présentent souvent des caractéristiques comme une

expression verbale facile, une sensibilité et une attention exacerbée, des

capacités visuo-spatiales élevées ou une mémoire importante. Néanmoins, ces capacités

ne sont pas toujours associées à un cursus scolaire réussi et peuvent s’accompagner

de troubles d’apprentissage et d’insertion sociale. Ainsi, deux profils ont été

proposés par F. Nusbaum : <b>le profil homogène</b> (les indices du QI sont élevés et comparables)

et <b>le profil hétérogène</b> (différence entre l’indice de compréhension verbale et

l’indice de raisonnement perceptif). </font></span></p><p style="text-align: justify; line-height: 1;"><span style="font-family: Arial, sans-serif; line-height: 1;"><font style="font-size: 13px;">La première étape de cette thèse consiste à

développer de méthodes de traitement d’IRM fonctionnelle de repos pour mesurer

la connectivité cérébrale chez l’enfant HP par la théorie des graphes. Le

coefficient de réorganisation topologique a été mesuré pour plusieurs métriques

afin d’évaluer les différences entre les réseaux cérébraux des enfants HP et

des enfants au QI standard. Des différences d’organisation ont été observées chez

les enfants HP dans le réseau cérébral global, hémisphérique et homotopique. En

particulier, les enfants HP hétérogènes montrent une baisse de connectivité

dans les régions préfrontale et pariétale gauche et une augmentation de la

connectivité homotopique des amygdales, structure des émotions. La deuxième étape

consiste en l’exploration des trois connectivités cérébrales, morphométrique,

structurale et fonctionnelle, chez l’adulte avec des techniques d’IRM

avancée à haute résolution spatiale et temporelle. Les relations entre ces marqueurs

de connectivité cérébrale et les données psychométriques seront explorées. Ces

résultats ont fait l’objet de présentations orales et de poster à des congrès

nationaux et internationaux spécialisés dans l’application des techniques d’IRM

clinique (SFRMBM, ESMRMB et ISMRM).</font></span></p><p style="text-align: justify;"><font style="font-size: 13px;"><span style="font-family: Arial, sans-serif;">Contact: </span><a href="mailto:suprano@creatis.insa-lyon.fr">suprano@creatis.insa-lyon.fr</a></font></p><p style="text-align: justify;"><br></p>

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<tr><td width="516"><v:rect style="width:516px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-70.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" style="padding-left:10px; padding-right:10px; font-size:16px;">

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<p style="text-align: justify; line-height: 100%;"><span style="font-family: Arial, sans-serif; line-height: 100%;"><font style="font-size: 13px;">Les <b>personnes à Haut

Potentiel (HP, QI > 130)</b> présentent souvent des caractéristiques comme une

expression verbale facile, une sensibilité et une attention exacerbée, des

capacités visuo-spatiales élevées ou une mémoire importante. Néanmoins, ces capacités

ne sont pas toujours associées à un cursus scolaire réussi et peuvent s’accompagner

de troubles d’apprentissage et d’insertion sociale. Ainsi, deux profils ont été

proposés par F. Nusbaum : <b>le profil homogène</b> (les indices du QI sont élevés et comparables)

et <b>le profil hétérogène</b> (différence entre l’indice de compréhension verbale et

l’indice de raisonnement perceptif). </font></span></p><p style="text-align: justify; line-height: 100%;"><span style="font-family: Arial, sans-serif; line-height: 100%;"><font style="font-size: 13px;">La première étape de cette thèse consiste à

développer de méthodes de traitement d’IRM fonctionnelle de repos pour mesurer

la connectivité cérébrale chez l’enfant HP par la théorie des graphes. Le

coefficient de réorganisation topologique a été mesuré pour plusieurs métriques

afin d’évaluer les différences entre les réseaux cérébraux des enfants HP et

des enfants au QI standard. Des différences d’organisation ont été observées chez

les enfants HP dans le réseau cérébral global, hémisphérique et homotopique. En

particulier, les enfants HP hétérogènes montrent une baisse de connectivité

dans les régions préfrontale et pariétale gauche et une augmentation de la

connectivité homotopique des amygdales, structure des émotions. La deuxième étape

consiste en l’exploration des trois connectivités cérébrales, morphométrique,

structurale et fonctionnelle, chez l’adulte avec des techniques d’IRM

avancée à haute résolution spatiale et temporelle. Les relations entre ces marqueurs

de connectivité cérébrale et les données psychométriques seront explorées. Ces

résultats ont fait l’objet de présentations orales et de poster à des congrès

nationaux et internationaux spécialisés dans l’application des techniques d’IRM

clinique (SFRMBM, ESMRMB et ISMRM).</font></span></p><p style="text-align: justify;"><font style="font-size: 13px;"><span style="font-family: Arial, sans-serif;">Contact: </span><a href="mailto:suprano@creatis.insa-lyon.fr">suprano@creatis.insa-lyon.fr</a></font></p><p style="text-align: justify;"><br></p>

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                                                                                        <font face="Arial"><b style="font-size: 23px;">Ilaria Suprano</b></font></div></td>

</tr><tr class="layout-block-vertical-spacer" style="height:8px;"><td width="254"><div class="spacer"></div></td>

</tr><tr><td width="254" class="layout-block-column"><div class="text" align="left" style="font-size: 16px; font-family: sans-serif;"><div style="text-align: left;"><font face="Arial, sans-serif" style="font-size: 13px;">Diplômée d’un master en Physique de l’Université Sapienza de Rome, Ilaria est actuellement en 3e année de thèse dans l’équipe « RMN et optique : de la mesure au biomarqueur ». </font><span style="font-family: Arial, sans-serif; text-align: justify;"><font style="font-size: 13px;">Ses travaux portent sur le développement de l’IRM fonctionnelle pour </font><b><font style="font-size: 13px;">la caractérisation du s</font><span style="font-size: 12px;">ubstrat neural de « l’intelligence » </span></b><span style="font-size: 12px;">via des mesures de connectivité cérébrale. </span></span><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fscholar.google.fr%2Fcitations%3Fuser=AzVWddwAAAAJ%26hl=fr/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/cGToEc-e8-sjod4NXzPBblpQsoo=96"><font face="Arial, sans-serif" style="font-size: 13px;">En savoir plus sur Ilaria…</font></a></div><div style="text-align: left;"><br></div></div></td>

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<p style="text-align: justify; margin: 0px;"><font face="Arial, sans-serif" style="font-size: 13px;"><b>Paul CHARBIT</b> a intégré <b>CREATIS</b> le 21/08/2018 en tant que

gestionnaire financier pour un premier emploi après avoir obtenu un BTS comptabilité

en mai 2018. Présent depuis quelques mois déjà, Paul a déjà démontré son

professionnalisme en appliquant rigoureusement les procédures du laboratoire.

Son objectif est de contribuer de manière bénéfique à l’activité du laboratoire

pour progresser dans sa toute jeune carrière professionnelle.</font></p>

<p style="text-align: justify; margin: 0px;"><font face="Arial, sans-serif" style="font-size: 13px;"><b>Sophie TRIFT</b> (photo) a rejoint l’équipe administrative le 12/11/2018

pour occuper pendant les 10 prochains mois le poste d’Assistante de Direction

en l’absence de Florine Gall. Pour avoir travaillé auparavant à la direction de

la Recherche à l’ENS et à la SFR Santé Lyon-Est à l’UCBL, l’univers de la

recherche lui est familier mais c’est sa première expérience au sein d’un

laboratoire. Sa devise : « il n’y a pas d’évolution, sans liberté d’essayer ».</font></p>

<p style="margin: 0px;"></p>

<div style="text-align: justify; line-height: 107%;"><font face="Arial, sans-serif" style="font-size: 13px;"><span style="line-height: 107%;"><b>Camille BENKAHLA </b>a partagé à mi-temps notre quotidien

pendant 3 mois afin de réaliser les différents supports de communications du

laboratoire (plaquette et brochure de CREATIS en Français et Anglais, plaquette

PILoT, kakémonos, modèle de présentation). Nous avons pu apprécier son dynamisme

et ses compétences qui ont abouti aux résultats que vous avez tous pu

constater. Nous lui souhaitons une excellent poursuite d’activité

professionnelle dans le cadre d’une mission à la Fabrique de l’Innovation.</span>    </font></div></div>

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<tr><td valign="top" class="layout-block-padded-column" align="center" width="125"><div class="layout-block-image"><img height="214" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-18.png" border="0" style="line-height: 1px; display: block;"  class="img-EQMST-CA312F6D-B674-41A7-B86C-D4697D0E8130" width="125"></img><div style="width:0px;height:0px;max-height:0;max-width:0;overflow:hidden;display:none;visibility:hidden;mso-hide:all;"></div></div></td><td class="layout-block-horizontal-spacer" width="10">  </td><td width="645" valign="top" align="left" class="layout-block-padded-column"><div class="text" style="font-size: 16px; font-family: sans-serif;">

<p style="text-align: justify; margin: 0px;"><font face="Arial, sans-serif" style="font-size: 13px;"><b>Paul CHARBIT</b> a intégré <b>CREATIS</b> le 21/08/2018 en tant que

gestionnaire financier pour un premier emploi après avoir obtenu un BTS comptabilité

en mai 2018. Présent depuis quelques mois déjà, Paul a déjà démontré son

professionnalisme en appliquant rigoureusement les procédures du laboratoire.

Son objectif est de contribuer de manière bénéfique à l’activité du laboratoire

pour progresser dans sa toute jeune carrière professionnelle.</font></p>

<p style="text-align: justify; margin: 0px;"><font face="Arial, sans-serif" style="font-size: 13px;"><b>Sophie TRIFT</b> (photo) a rejoint l’équipe administrative le 12/11/2018

pour occuper pendant les 10 prochains mois le poste d’Assistante de Direction

en l’absence de Florine Gall. Pour avoir travaillé auparavant à la direction de

la Recherche à l’ENS et à la SFR Santé Lyon-Est à l’UCBL, l’univers de la

recherche lui est familier mais c’est sa première expérience au sein d’un

laboratoire. Sa devise : « il n’y a pas d’évolution, sans liberté d’essayer ».</font></p>

<p style="margin: 0px;"></p>

<div style="text-align: justify; line-height: 107%;"><font face="Arial, sans-serif" style="font-size: 13px;"><span style="line-height: 107%;"><b>Camille BENKAHLA </b>a partagé à mi-temps notre quotidien

pendant 3 mois afin de réaliser les différents supports de communications du

laboratoire (plaquette et brochure de CREATIS en Français et Anglais, plaquette

PILoT, kakémonos, modèle de présentation). Nous avons pu apprécier son dynamisme

et ses compétences qui ont abouti aux résultats que vous avez tous pu

constater. Nous lui souhaitons une excellent poursuite d’activité

professionnelle dans le cadre d’une mission à la Fabrique de l’Innovation.</span>    </font></div></div></td>

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                        <div width="100%" class="desktop-only">

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                                                <td width="10"> </td>

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                                                                                                        <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';"><span style="font-size: 13px; font-family: Arial, sans-serif;">Contact: </span><font color="#034dff" style="font-size: 13px; font-family: Arial, sans-serif;"><b><a href="mailto:communication@creatis.insa-lyon.fr">communication@creatis.insa-lyon.fr</a> </b></font><span style="font-size: 13px; font-family: Arial, sans-serif;"> </span><br><div><font face="Arial, sans-serif" style="font-size: 13px;">Laboratoire situé sur le campus LyonTech La Doua: <a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.google.com%2Fmaps%2Fd%2Fviewer%3Fll=45.782205%252C4.870999%26spn=0.008949%252C0.017638%26hl=fr%26msa=0%26z=16%26ie=UTF8%26mid=1YEoxug8SWBQqfFPC7fOjpe-Ibz8/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/zJ6GXTtH1bZGJC3yjpv-xcaV0U8=96">plan Google-maps</a>, les Hospices Civils de Lyon (HCL), Grenoble (cyclotron), Saint-Etienne (CHU de Saint-Etienne).</font></div></div>

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                                                                                        </tr>

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                                                                                <table width="250" cellspacing="0" cellpadding="0" align="left" class="layout-block-padded-column">

                                                                                        <tbody><tr class="layout-block-vertical-spacer" style="display:none; height:0px;">

                                                                                                <td width="250"><div class="spacer"></div></td>

                                                                                        </tr>

                                                                                        <tr>

                                                                                                <td align="left" valign="top" width="250">

                                                                                                        <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';"><div><font face="Arial, sans-serif" style="font-size: 13px;"><b>Adresse principale:</b></font></div><div><font face="Arial, sans-serif" style="font-size: 13px;">CREATIS (Direction)- Site INSA</font></div><div><font face="Arial, sans-serif" style="font-size: 13px;">Bâtiment Blaise Pascal (502, 4ème étage)</font></div><div><font face="Arial, sans-serif" style="font-size: 13px;">7 avenue Jean Capelle</font></div><div><font face="Arial, sans-serif" style="font-size: 13px;">69621 Villeurbanne cedex F</font><font face="Arial, sans-serif" style="font-size: 14px;">RANCE</font></div></div>

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                                                                                                <td width="10" class="layout-block-horizontal-spacer" style="line-height:1px;"> </td>

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                                                                                <table width="209" cellspacing="0" cellpadding="0" align="left" class="layout-block-padded-column">

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                                                                                                <td width="209"><div class="spacer"></div></td>

                                                                                        </tr>

                                                                                        <tr>

                                                                                                <td align="left" valign="top" class="layout-block-padded-column" width="209">

                                                                                                        <div  class="text" style="font-size: 16px; font-family: 'Lucida Grande';"><div><font face="Arial, sans-serif" style="font-size: 13px;"><b>Accueil</b> : Marion LISSAC</font></div><div><font face="Arial, sans-serif" style="font-size: 13px;">Tel. : +33 (0)4 72 43 82 27</font></div><div><font face="Arial, sans-serif" style="font-size: 13px;">Fax : +33 (0)4 72 43 85 26</font></div><div><a href="http://w99zwhhy.r.eu-west-1.awstrack.me/L0/http:%2F%2Fmarion.lissac@creatis.insa-lyon.fr/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/m8DeDt-DigHttXJQfAYfwJRM8aQ=96"><font face="Arial, sans-serif" style="font-size: 13px;">marion.lissac@creatis.insa-lyon.fr</font></a></div></div>

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<tr><td width="10" class="layout-block-padding-left">  </td><td width="780" valign="top" align="left" class="layout-block-content-cell"><v:rect style="width:780px;" stroke="f"><v:fill type="tile" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/box-bg-58.jpg" color="#ffffff"></v:fill><v:textbox style="mso-fit-shape-to-text:true" inset="0,0,0,0"><div><div style="font-size:0"><table cellspacing="0" cellpadding="0" class="layout-block-box-padding">

<tr><td style="font-size:1px;" width="10">  </td><td align="left" valign="top" class="layout-block-padded-column" width="281"><div class="text" style="font-size: 16px; font-family: sans-serif;"><span style="font-size: 13px; font-family: Arial, sans-serif;">Contact: </span><font color="#034dff" style="font-size: 13px; font-family: Arial, sans-serif;"><b><a href="mailto:communication@creatis.insa-lyon.fr">communication@creatis.insa-lyon.fr</a> </b></font><span style="font-size: 13px; font-family: Arial, sans-serif;"> </span><br><div><font face="Arial, sans-serif" style="font-size: 13px;">Laboratoire situé sur le campus LyonTech La Doua: <a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.google.com%2Fmaps%2Fd%2Fviewer%3Fll=45.782205%252C4.870999%26spn=0.008949%252C0.017638%26hl=fr%26msa=0%26z=16%26ie=UTF8%26mid=1YEoxug8SWBQqfFPC7fOjpe-Ibz8/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/du_vGrzCG7GAZnt3E0HkKI6-Azc=96">plan Google-maps</a>, les Hospices Civils de Lyon (HCL), Grenoble (cyclotron), Saint-Etienne (CHU de Saint-Etienne).</font></div></div></td><td class="layout-block-horizontal-spacer" width="10">  </td><td width="250" align="left" valign="top"><div class="text" style="font-size: 16px; font-family: sans-serif;"><div><font face="Arial, sans-serif" style="font-size: 13px;"><b>Adresse principale:</b></font></div><div><font face="Arial, sans-serif" style="font-size: 13px;">CREATIS (Direction)- Site INSA</font></div><div><font face="Arial, sans-serif" style="font-size: 13px;">Bâtiment Blaise Pascal (502, 4ème étage)</font></div><div><font face="Arial, sans-serif" style="font-size: 13px;">7 avenue Jean Capelle</font></div><div><font face="Arial, sans-serif" style="font-size: 13px;">69621 Villeurbanne cedex F</font><font face="Arial, sans-serif" style="font-size: 14px;">RANCE</font></div></div></td><td width="10" class="layout-block-horizontal-spacer">  </td><td width="209" align="left" valign="top" class="layout-block-padded-column"><div class="text" style="font-size: 16px; font-family: sans-serif;"><div><font face="Arial, sans-serif" style="font-size: 13px;"><b>Accueil</b> : Marion LISSAC</font></div><div><font face="Arial, sans-serif" style="font-size: 13px;">Tel. : +33 (0)4 72 43 82 27</font></div><div><font face="Arial, sans-serif" style="font-size: 13px;">Fax : +33 (0)4 72 43 85 26</font></div><div><a href="http://w99zwhhy.r.eu-west-1.awstrack.me/L0/http:%2F%2Fmarion.lissac@creatis.insa-lyon.fr/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/itIJOabDF26QENP-59bByDRCNoI=96"><font face="Arial, sans-serif" style="font-size: 13px;">marion.lissac@creatis.insa-lyon.fr</font></a></div></div></td><td style="font-size:1px;" width="10">  </td>

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                                                                                <a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.facebook.com%2F%3Fstype=lo%26jlou=AffZ_FqtMZQBXBixu363GnbNS0W1s1Hi8M2oDC9mv6eBHKpc9rpGSckmAJQzH1QFpeWZNBjmP3mXCAiB2A9nqJXR%26smuh=45558%26lh=Ac_PailCsRNT4qbA/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/qDnW7-38uG2ASnWWLG_8ffrLHL0=96"><img width="272" height="56" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-3.png" border="0" style="line-height: 1px; display: block; width: 272px; height: 56px;"></a>

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<tr><td width="800"><table width="800" cellspacing="0" cellpadding="0">

<tr><td valign="top" class="layout-block-column" align="center" width="272"><div class="layout-block-image"><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.facebook.com%2F%3Fstype=lo%26jlou=AffZ_FqtMZQBXBixu363GnbNS0W1s1Hi8M2oDC9mv6eBHKpc9rpGSckmAJQzH1QFpeWZNBjmP3mXCAiB2A9nqJXR%26smuh=45558%26lh=Ac_PailCsRNT4qbA/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/hJEiRARmSeEwkfh57OEfGjxsujs=96"><img height="56" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-3.png" border="0" style="line-height: 1px; display: block;" class="img-EQMST-4465CFEC-D8D9-4E57-9D05-1D7B99F10FE4" width="272"></img><div style="width:0px;height:0px;max-height:0;max-width:0;overflow:hidden;display:none;visibility:hidden;mso-hide:all;"></div></a></div></td><td width="274" valign="top" class="layout-block-column" align="center"><div class="layout-block-image"><a href="http://"><img height="57" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-19.png" border="0" style="display: block;" class="img-EQMST-4F3163EB-17FB-44A2-A418-DFEDC7B060C8" width="274"></img><div style="width:0px;height:0px;max-height:0;max-width:0;overflow:hidden;display:none;visibility:hidden;mso-hide:all;"></div></a></div></td><td width="254" valign="top" class="layout-block-column" align="center"><div class="layout-block-image"><a href="https:// www.creatis.insa-lyon.fr"><img height="57" alt="" src="https://storage.maildesigner365.com/templates/team/73c7d353-234e-45c9-8418-d0987123fd43/b61024af-ccbc-41d7-99e0-9360f7e9a99b/e15b5111-2a4a-11e9-b1ee-22bcb034e0a1/image-20.png" border="0" style="display: block;" class="img-EQMST-ACB26C79-9957-4E4C-A137-5FE1D6FB03A7" width="254"></img><div style="width:0px;height:0px;max-height:0;max-width:0;overflow:hidden;display:none;visibility:hidden;mso-hide:all;"></div></a></div></td>

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                                                                                                                <span style="font-size: 14px;"><font face="Arial"><b>CREATIS © 2016  </b>                    | <a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.creatis.insa-lyon.fr%2Fmailman%2Flistinfo%2Fnewsletter/1/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/wGXutkQNtAHp1AIk3_5_v5H7D9Q=96"><b>S’inscrire</b></a><b> / </b><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.creatis.insa-lyon.fr%2Fmailman%2Flistinfo%2Fnewsletter/2/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/7UMcs5_vBq7UpZ5rMOnu-My_isM=96"><b>Se désincrire</b></a><b> ou</b> envoyer un courriel à: <font color="#034dff"><b><a href="mailto:communication@creatis.insa-lyon.fr">communication@creatis.insa-lyon.fr</a> </b></font></font><span style="font-family: Arial;">                             </span></span></div>

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                                                                                                                <span style="font-size: 14px;"><font face="Arial"><b>CREATIS © 2016  </b>                    | <a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.creatis.insa-lyon.fr%2Fmailman%2Flistinfo%2Fnewsletter/3/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/poVtQReQtK9Wf-8WJbVaJjbYxPk=96"><b>S’inscrire</b></a><b> / </b><a href="https://w99zwhhy.r.eu-west-1.awstrack.me/L0/https:%2F%2Fwww.creatis.insa-lyon.fr%2Fmailman%2Flistinfo%2Fnewsletter/4/01020168c46ccfed-3e3ac330-f931-40d9-a993-58fce7c161f2-000000/whsp3ax7QNkCAq9KKmjf4qrzQHg=96"><b>Se désincrire</b></a><b> ou</b> envoyer un courriel à: <font color="#034dff"><b><a href="mailto:communication@creatis.insa-lyon.fr">communication@creatis.insa-lyon.fr</a> </b></font></font><span style="font-family: Arial;">                             </span></span></div></td><td style="font-size:1px;" width="10">  </td>

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