Objectives
The objectives of the team are to improve the understanding of complex phenomena obtained in the near-field in the case of magnetism for Magnetic Resonance (RF field) or in the far field in the case of optical imaging. The underlying challenge is the weak interaction with the media under investigation, whether it be in MR or optics, and thus yielding a low signal to noise ratio. Researches carried out endeavor to improve this SNR through the development of new systems or methods. The addressed modalities are operated in synergy to provide, in vivo, relevant metabolic and functional information in addition to anatomy. Methods used pertain to MR signal coding theory, electromagnetic simulations, radio frequency and optoelectronic devices design, and also NMR signal processing for reliable quantification of relevant parameters. We develop morphological, functional and interventional imaging for liver, gastro-intestinal wall exploration, musculosqueletal characterization as well as brain functional imaging. The work carried out in this team is focused on new instruments and methodology developments in the domain of biomedical imaging. In NMR as well as in optics, the goal is to improve the quantity and quality of acquired in vivo information in animal models and human subjects. Optical instrumentation is also specifically developed to design and build multimodal systems. Thus, the accent is put on the development of miniaturized coils (array and endoluminal) for new imaging and spectroscopic methods using MR as well as combining MR and optics. Novel acquisition schemes and signal processing quantification methods are designed in tight interaction with the experimental constraints.
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