<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Komlev, V.S.</style></author><author><style face="normal" font="default" size="100%">Maddalena Mastrogiacomo</style></author><author><style face="normal" font="default" size="100%">Peyrin, F.</style></author><author><style face="normal" font="default" size="100%">Ranieri Cancedda</style></author><author><style face="normal" font="default" size="100%">Franco Rustichelli</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">X-Ray Synchrotron Radiation Pseudo-Holotomography as a New Imaging Technique to Investigate Angio- and Microvasculogenesis with No Usage of Contrast Agents</style></title><secondary-title><style face="normal" font="default" size="100%">Tissue Eng Part C, Methods</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">categ_st2i</style></keyword><keyword><style  face="normal" font="default" size="100%">Imagerie tomographique et thérapie par rayonnement</style></keyword><keyword><style  face="normal" font="default" size="100%">reseau_international</style></keyword><keyword><style  face="normal" font="default" size="100%">structure_os</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2009</style></year><pub-dates><date><style  face="normal" font="default" size="100%">feb</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/19231984</style></url></web-urls></urls><number><style face="normal" font="default" size="100%">3</style></number><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">425-430</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Standard X-ray micro-computed tomography is a technique that allows a good visualization of the structure of mineralized tissues and biomaterials, but it fails to finely discern soft tissues. Here, we used X-ray synchrotron radiation pseudo-holotomography to visualize, at three-dimensional {(3D)} level, microvascular networks for the first time with no need for contrast agents, and to extract quantitative structural data in a bone-engineered construct implanted for 24 weeks in a mouse. When compared to standard histology, pseudo-holotomography allowed a previously unavailable {3D} resolution of the vessels, which in turn appeared more clearly visible. Thus, pseudo-holotomography is an innovative technique that offers a promising powerful tool to investigate angio- and microvasculogenesis in advanced biomedical research areas such as regenerative medicine and antiangiogenic cancer therapies.</style></abstract></record></records></xml>