The ANR project SPECT-Motion-eDCC is a collaborative project between CREATIS, TIMC, OHI and LUMEN. Single photon emission computed tomography (SPECT) is a technique for imaging the 3D distribution of a radioactive tracer that has been administered to a patient to track certain biological functions. The long acquisition times (10-40 minutes) of SPECT make them prone to patient motion which decreases image quality. Exponential data consistency conditions (eDCC) are mathematical equations  that should be verified by the input data of SPECT reconstruction algorithms. Inconsistencies might be used to correct input data, e.g., to improve correction of the attenuation .
The goal of this postdoc fellowship is to implement motion correction in SPECT reconstruction using eDCC-based motion estimation. The investigations will start with Monte Carlo simulations of clinical SPECT scanners with a parallel collimator as those available at the LUMEN. Application to real data and pinhole SPECT will be investigated subsequently.
- Select patient data from which SPECT acquisitions will be simulated,
- Simulate SPECT projections with patient motion using GATE,
- Implement motion correction in SPECT reconstruction with RTK
- Education: PhD in applied mathematics, computer sciences or medical physics.
- Scientific interests: applied mathematics, computer sciences (medical image processing), medical physics.
- Programming skills: Python, C++ (ITK, RTK).
- Languages: command of English required, French optional.
- Supervision: Simon Rit
- Location: Mainly at the Centre Léon Bérard, Lyon, France.
- Period: 1 year, starting as soon as possible.
- Salary (net): depending on experience, starting 2100 euros/month.
- Send CV and a brief statement of interest on https://bit.ly/3uhilhW
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 R.G. Wells and R. Clackdoyle. Feasibility of attenuation map alignment in pinhole cardiac SPECT using exponential data consistency conditions. Med Phys, 48(9):4955–4965, 2021.