{"id":16,"date":"2010-12-08T15:40:40","date_gmt":"2010-12-08T15:40:40","guid":{"rendered":"http:\/\/www.creatis.insa-lyon.fr\/~grenier\/?page_id=16"},"modified":"2026-02-16T15:20:35","modified_gmt":"2026-02-16T14:20:35","slug":"research","status":"publish","type":"page","link":"https:\/\/www.creatis.insa-lyon.fr\/~grenier\/?page_id=16","title":{"rendered":"Research"},"content":{"rendered":"\n<figure class=\"wp-block-image size-full is-resized wp-duotone-000000-00a5ff-1\"><img loading=\"lazy\" decoding=\"async\" width=\"1000\" height=\"500\" src=\"https:\/\/www.creatis.insa-lyon.fr\/~grenier\/wp-content\/uploads\/AppSupervised_1000-500.png\" alt=\"\" class=\"wp-image-617\" style=\"width:727px;height:364px\" srcset=\"https:\/\/www.creatis.insa-lyon.fr\/~grenier\/wp-content\/uploads\/AppSupervised_1000-500.png 1000w, https:\/\/www.creatis.insa-lyon.fr\/~grenier\/wp-content\/uploads\/AppSupervised_1000-500-300x150.png 300w, https:\/\/www.creatis.insa-lyon.fr\/~grenier\/wp-content\/uploads\/AppSupervised_1000-500-768x384.png 768w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><\/figure>\n\n\n<p>My research topics primarily focus on the automatic segmentation of multidimensional medical data, with applications in pathology understanding, follow-up, and digital twin development. These topics are part of the team <a href=\"https:\/\/www.creatis.insa-lyon.fr\/site7\/fr\/myriad\">Myriad.<\/a><\/p>\n<p>A significant part of my work has been dedicated to Mean-shift, which is an exciting approach that does not require assumptions about the data. Mean-shift can be derived in a <em>knowledge discovery<\/em> framework. Extending this framework to spatiotemporal data, scale, and space selections, with the integration of a few prior, constituted my main research. Such methods are motivated by medical challenges ( Multiple sclerosis, stroke, cardiac segmentation&#8230;. ).<\/p>\n<p>Now, I am focusing on approaches based on deep learning for segmentation, filtering, and localization\/detection tasks that can provide better and more robust results than many conventional approaches. The main challenges are the use of semi- and weakly-supervised methods, dealing with experts&#8217; disagreements, explainability, confidence, and trying to train in a playful manner (selection of needed data, continuous learning, &#8230;). The applications of such segmentations are: pathologies understanding and quantification, longitudinal analysis (disease evolution, clinical care), and more and more for numerical simulations (CFD, failure load&#8230;: digital twin).\u00a0<\/p>\n<p>For image processing application development, my background is on <a href=\"http:\/\/www.itk.org\/\">ITK <\/a>and <a href=\"https:\/\/opencv.org\/\">OpenCV<\/a>, with <a href=\"http:\/\/qt.nokia.com\/products\/developer-tools\/\">QTCreator<\/a> and <a href=\"https:\/\/cmake.org\/\">CMake<\/a> for C++, under Windows and Linux. I use more and more Python with conda and really appreciate the<em> jupyter lab<\/em> environment (debuging and contextual help !).<\/p>\n<p>For deep learning, I mostly use Python with <a href=\"https:\/\/keras.io\/\">Keras<\/a>\/<a href=\"https:\/\/www.tensorflow.org\/\">Tensorflow<\/a> (using <a href=\"https:\/\/docs.conda.io\/en\/latest\/\">conda<\/a>), or <a href=\"https:\/\/monai.io\/\">MONAI\u00a0<\/a>. For Yolo, I switch from <a href=\"https:\/\/github.com\/AlexeyAB\">AlexeyAB Darknet<\/a> lib to <a href=\"https:\/\/docs.ultralytics.com\/fr\/\">Ultralytics<\/a> one.<\/p>\n<h3>Topics<\/h3>\n<ul>\n<li class=\"cat-item cat-item-17\"><a href=\"https:\/\/www.creatis.insa-lyon.fr\/~grenier\/?cat=17\" target=\"_blank\" rel=\"noreferrer noopener\">Deep learning<\/a><\/li>\n<li class=\"cat-item cat-item-7\"><a href=\"https:\/\/www.creatis.insa-lyon.fr\/~grenier\/?cat=7\" target=\"_blank\" rel=\"noreferrer noopener\">Mean Shift<\/a><\/li>\n<li class=\"cat-item cat-item-8\"><a href=\"https:\/\/www.creatis.insa-lyon.fr\/~grenier\/?cat=8\" target=\"_blank\" rel=\"noreferrer noopener\">Region Growing<\/a><\/li>\n<li class=\"cat-item cat-item-12\"><a href=\"https:\/\/www.creatis.insa-lyon.fr\/~grenier\/?cat=12\" target=\"_blank\" rel=\"noreferrer noopener\">Restoration<\/a><\/li>\n<li class=\"cat-item cat-item-14\"><a href=\"https:\/\/www.creatis.insa-lyon.fr\/~grenier\/?cat=14\" target=\"_blank\" rel=\"noreferrer noopener\">Spatiotemporal<\/a><\/li>\n<\/ul>\n<h3>Bibliography<\/h3>\n<ul>\n<li><a href=\"https:\/\/scholar.google.com\/citations?user=gwfEQ8sAAAAJ&amp;hl=fr&amp;oi=ao\">Google Scholar <\/a><\/li>\n<li><a href=\"https:\/\/orcid.org\/0000-0002-3630-5856\">ORCID iD<\/a><\/li>\n<li><a href=\"https:\/\/cv.archives-ouvertes.fr\/thomas-grenier\">HAL<\/a><\/li>\n<li><a href=\"http:\/\/www.researcherid.com\/rid\/H-4456-2014\">Researcher ID<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>My research topics primarily focus on the automatic segmentation of multidimensional medical data, with applications in pathology understanding, follow-up, and digital twin development. These topics are part of the team Myriad. A significant part of my work has been dedicated to Mean-shift, which is an exciting approach that does not require assumptions about the data. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"templates\/template-full-width.php","meta":{"footnotes":""},"class_list":["post-16","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.creatis.insa-lyon.fr\/~grenier\/index.php?rest_route=\/wp\/v2\/pages\/16","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.creatis.insa-lyon.fr\/~grenier\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.creatis.insa-lyon.fr\/~grenier\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.creatis.insa-lyon.fr\/~grenier\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.creatis.insa-lyon.fr\/~grenier\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=16"}],"version-history":[{"count":34,"href":"https:\/\/www.creatis.insa-lyon.fr\/~grenier\/index.php?rest_route=\/wp\/v2\/pages\/16\/revisions"}],"predecessor-version":[{"id":1709,"href":"https:\/\/www.creatis.insa-lyon.fr\/~grenier\/index.php?rest_route=\/wp\/v2\/pages\/16\/revisions\/1709"}],"wp:attachment":[{"href":"https:\/\/www.creatis.insa-lyon.fr\/~grenier\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=16"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}