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Publications of L. Derex
Articles in journal
  1. [CHO-09b] T.H. Cho, M. Hermier, J.A. Alawneh, T. Ritzenthaler, V. Desestret, L. Ostergaard, L Derex, J.C. Baron, and N. Nighoghossian. Total Mismatch. Negative Diffusion-Weighted Imaging but Extensive Perfusion Defect in Acute Stroke. Stroke, 40(10):(3400-3402), 2009.


  2. [CHO-09a] T.H. Cho, N. Nighoghossian, N. Tahon, C. Nemoz, M. Hermier, F. Salkine, L. Derex, P. Trouillas, J.C. Froment, and F. Turjman. Brain stem diffusion-weighted imaging lesion score: a potential marker of outcome in acute basilar artery occlusion. Am J Neuro Radiol, 30:194-198, 2009.


  3. [DERE-09] L. Derex and N. Nighoghossian. Thrombolysis, stroke-unit admission and early rehabilitation in elderly patients. Nat Rev Neurol, 5(9):(506-511), 2009.


  4. [DERE-09b] I.C. Ralea, G. Rioufol, S. Cakmak, L. Derex, and N. Nighoghossian. Acute stroke and heart attack management within a four-hour time window. J Stroke Cerebrovasc Dis, 18(2):(167-70), 2009.


  5. [RITZ-09a] T. Ritzenthaler, N. Nighoghossian, J. Berthiller, A.M. Schott, T.H. Cho, L. Derex, J. Brun, P. Trouillas, and B. Claustrat. Nocturnal urine melatonin and 6-sulphatoxymelatonin excretion at the acute stage of ischaemic stroke. J Pineal Res, 40(5):(1834-41), 2009.


  6. [SING-09] O.C. Singer, J Berkefeld, M.W. Lorenz, J. Fiehler, G.W. Albers, M.G. Lansberg, A. Kastrup, A. Rovira, D.S. Liebeskind, A. Gass, C. Rosso, L. Derex, J.S. Kim, and T. Neumann-Haefelin. Imaging anatomy of cranial nerves. Cerebrovasc Dis, 132(1):(368-74), 2009.


  7. [NIGH-08d] N. Nighoghossian and L. Derex. Intracerebral haemorrhage after thrombolysis for acute ischaemic stroke: an update. J Neurol Neurosur Ps, 79(10):(1093-9), 2008.


  8. [RALE-08] I.C. Ralea, N. Nighoghossian, F. Tahon, L. Derex, S. Cakmak, P. Trouillas, and Turjman F.. Stenting of symptomatic basilar and vertebral artery stenosis in patients resistant to optimal medical prevention: the Lyon stroke unit experience. Eur Neurol, 60(3):(27-31), 2008.


  9. [CHO-07a] T.H. Cho, N. Nighoghossian, M. Wiart, V. Desestret, S. Cakmak, Y. Berthezène, L. Derex, G. Louis-Tisserand, P. Trouillas, J. Honnorat, J.C. Froment, and M. Hermier. USPIO-enhanced MRI of neuroinflammation at the sub-acute stage of ischemic stroke, preliminary data. Cerebrovasc Dis, 24(6):544-546, 2007.


  10. [NIGH-07a] N. Nighoghossian, M. Wiart, S. Cakmak, Y. Berthezène, L. Derex, T.H. Cho, C. Nemoz, F. Chappuis, J.L. Tisserand, J.B. Pialat, P. Trouillas, J.C. Froment, and M. Hermier. Inflammatory response after ischemic stroke: a USPIO-enhanced MRI study in patients. Stroke, 38(2):303-307, 2007.


  11. [MECH-06] L. Mechtouff, M. Hermier, B Nader, S Cartalat, L. Derex, S. Cakmak, J. Honnorat, and N. Nighoghossian. Stroke MRI may result in a therapeutic dilemma. Eur Neurol, 56(4):(235), 2006.


  12. [NIGH-06e] N. Nighoghossian, L. Derex, and P. Douek. The vulnerable carotid artery plaque : current imaging methods and new perspective. Stroke, 36(12):2764-2772, 2006.


  13. [NIGH-06a] N. Nighoghossian, L. L. Zeng, L. Derex, S. Cakmak, and P. Trouillas. Warning Compulsive Behaviour Preceding Acute Ischemic Stroke. Eur Neurol, 56(1):340-347, 2006.


  14. [RHEI-06] S. Rheims, N. Nighoghossian, M. Hermier, M. Formaglio, S. Cakmak, L. Derex, and P. Trouillas. Reversible acute postpartum cerebral angiopathy. Rev Neurol (Paris), 162(10):(1014-8), 2006.


  15. [SERF-06] J. M. Serfaty, M. Nonent, N. Nighoghossian, F. Rouhart, L. Derex, C. Rotaru, P. Chirossel, G. Thabut, B. Guias, J.F. Heautot, P. Gouny, A. De La Vega, C. Pachai, R. Ecochard, J. Villard, and P. Douek. Plaque density on CT, a potential marker of ischemic stroke. Neurology, 66(1):118-120, 2006.


  16. [DERE-05] L. Derex, M. Hermier, P. Adeleine, J.B. Pialat, M. Wiart, Y. Berthezène, F. Philippeau, J. Honnorat, J.C. Froment, P. Trouillas, and N. Nighoghossian. Clinical and imaging predictors of intracerebral haemorrhage in stroke patients treated with intravenous tissue plasminogen activator. J Neurol Neurosur Ps, 76:70-75, 2005.


  17. [HERM-05] M. Hermier, N. Nighoghossian, L. Derex, M. Wiart, C. Nemoz, Y. Berthezène, and J.C. Froment. Hypointense leptomeningeal vessels at T2*-weighted MRI in acute ischemic stroke. Neurology, 65:652-653, 2005.


  18. [PIAL-05] J.B. Pialat, M. Wiart, N. Nighoghossian, P. Adeleine, L. Derex, M. Hermier, J.C. Froment, and Y. Berthezène. Evolution of Lesion Volume in Acute Stroke Treated by Intravenous t-PA. J Magn Reson Imaging, 22:23-28, 2005.


  19. [CAKM-04] S. Cakmak, M. Hermier, A. Montavont, L. Derex, F. Mauguière, P. Trouillas, and N. Nighoghossian. T2* weighted MRI in cortical thrombosis. Neurology, 63:1698, 2004.


  20. [DERE-04b] L. Derex, M. Hermier, P. Adeleine, J.B. Pialat, M. Wiart, Y. Berthezène, J.C. Froment, P. Trouillas, and N. Nighoghossian. Influence of the site of arterial occlusion on multiple baseline hemodynamic MRI parameters and post-thrombolytic recanalization in acute stroke. Neuroradiology, 46:883-887, 2004.


  21. [HONN-04] L. Derex, N. Nighoghossian, M. Hermier, P. Adeleine, Y. Berthezène, F. Philippeau, J. Honnorat, J.C. Froment, and P. Trouillas. Influence of pre-treatment MRI parameters on clinical outcome, recanalization and infarct size in 49 stroke patients treated by intravenous tissue plasminogen activator. J Neurol Sci, 225(1-2):3-9, 2004.


  22. [DERE-04c] L. Derex, N. Nighoghossian, M. Hermier, P. Adeleine, F. Philippeau, J. Honnorat, H. Yilmaz, P. Dardel, J.C. Froment, and P. Trouillas. Thrombolysis for ischemic stroke in patients with old microbleeds on pretreatment MRI. Cerebrovasc Dis, 17:238-241, 2004.


  23. [DERE-04a] L. Derex, N. Nighoghossian, M. Hermier, J.B. Pialat, M. Wiart, F. Philippeau, P. Adeleine, J. Honnorat, J.C. Froment, Y. Berthezène, and P. Trouillas. Magnetic Resonance Imaging: Significance of Early Ischemic Changes on Computed Tomography. Cerebrovasc Dis, 18:232-235, 2004.


  24. [MONT-04g] A. Montavont, N. Nighoghossian, L. Derex, M. Hermier, J. Honnorat, F. Philippeau, M. Belo, F. Turjman, P. Adeleine, J.C. Froment, and P. Trouillas. Intravenous rt-PA in vertebrobasilar acute infarcts. Neurology, 62:1854-1856, 2004.


  25. [NONE-04] M. Nonent, J.M. Serfaty, N. Nighoghossian, L. Derex, and P. Douek. Concordance rate differences of three non invasive imaging techniques to measure carotid stenosis in clinical routine. Results of the CARMEDAS multicenter study. Stroke, pp 682-686, 2004.


  26. [CAKM-03] S. Cakmak, L. Derex, M. Berruyer, N. Nighoghossian, F. Philippeau, P. Adeleine, M. Hermier, J.C. Froment, and P. Trouillas. Cerebral venous thrombosis : clinical outcome and systematic screening of prothrombotic factors. Neurology, 60:1175-1177, 2003.


  27. [HERM-03b] M. Hermier, A.S. Ibrahim, M. Wiart, P. Adeleine, F. Cotton, P. Dardel, L. Derex, Y. Berthezène, N. Nighoghossian, and J.C. Froment. The delayed perfusion sign at MRI : a potential marquer of collateral leptomeningeal blood flow in acute stroke ?. J Neuroradiol, 30(3):172-179, 2003.


  28. [HERM-03a] M. Hermier, N. Nighoghossian, P. Adeleine, Y. Berthezène, L. Derex, H. Yilmaz, J.F. Dugor, P. Dardel, F. Cotton, F. Philippeau, P. Trouillas, and J.C. Froment. Early magnetic resonance imaging prediction of arterial recanalization and late infarct volume in acute carotid artery stroke. J Cereb Blood Flow Metab, 23(2):240-248, 2003.


  29. [HERM-03d] M. Hermier, N. Nighoghossian, L. Derex, P. Adeleine, M. Wiart, Y. Berthezène, F. Cotton, J. B. Pialat, P. Trouillas, and J.C. Froment. Hypointense transcerebral veins at T2* weighted MRI: a marquer of hemorrhagic transformation risks in patients treated by IV tissu plasminogen activator. J Cereb Blood Flow Metab, 23(11):1362-1370, 2003.


  30. [MONT-03g] A. Montavont, N. Nighoghossian, M. Hermier, L. Derex, F. Philippeau, J. Honnorat, Y. Berthezène, J.C. Froment, L. Caplan, and P. Trouillas. Hemiplegia in posterior cerebral artery occlusion : acute diffusion and perfusion MRI assessment. Cerebrovasc Dis, 16:452-453, 2003.


  31. [NIGH-03a] N. Nighoghossian, M. Hermier, P. Adeleine, L. Derex, J.F. Dugor, F. Philippeau, H. Yilmaz, J. Honnorat, P. Dardel, Y. Berthezène, J.C. Froment, and P. Trouillas. Baseline magnetic resonance imaging parameters and stroke outcome in patients treated by intravenous tissue plasminogen activator. Stroke, 34(2):458-463, 2003.


  32. [DERE-02a] L. Derex, P. Adeleine, N. Nighoghossian, J. Honnorat, and P. Trouillas. Factors influencing early admission in a french stroke unit. Stroke, 33:153-159, 2002.


  33. [DERE-02c] L. Derex, N. Nighoghossian, M. Hermier, P. Adeleine, J.C. Froment, and P. Trouillas. Early detection of cerebral arterial occlusion on magnetic resonance angiography. Predictive value of the baseline NIHSS score and impact on neurological outcome. Cerebrovasc Dis, 13(4):225-229, 2002.


  34. [NIGH-02a] N. Nighoghossian, M. Hermier, P. Adeleine, K. Blanc-Lasserre, L. Derex, J. Honnorat, F. Philippeau, J. F. Dugor, J.C. Froment, and P. Trouillas. Old microbleeds, a potential factor of cerebral bleeding after ischemic stroke. A gradient-echo T2*-weighted brain MRI study. Stroke, 33:735-742, 2002.


  35. [DERE-01a] L. Derex, N. Nighoghossian, M. Perinetti, J. Honnorat, and P. Trouillas. Thrombolytic therapy in acute ischemic stroke patients with cardiac thrombus. Neurology, 57:2122-2125, 2001.


  36. [DERE-01b] L. Derex, A. Thomas, G.T. Brott, A. Christopher, M. Lewandovski, and R. Frankel. Outcome of Stroke patients without angiographically revealed arterial occlusion within four hours of symptom onset. Am J Neuro Radiol, 22:685-690, 2001.


  37. [HERM-01] M. Hermier, N. Nighoghossian, L. Derex, Y. Berthezène, K. Blanc-Lasserre, P. Trouillas, and J.C. Froment. MRI of acute post-ischemic cerebral hemorrhage in stroke patient : diagnosis with T2*-weighted gradient-echo sequences. Neuroradiology, 43:809-815, 2001.


  38. [NIGH-01a] N. Nighoghossian, M. Hermier, Y. Berthezène, M. Wiart, L. Derex, J. Honnorat, P. Trouillas, F. Turjman, and J.C. Froment. Early diagnosis of hemorrhagic transformation. Diffusion/perfusion weighted MRI versus CT-Scan. Cerebrovasc Dis, 11(3):151-156, 2001.


  39. [BLAN-00] K. Blanc-Lasserre, N. Nighoghossian, L. Derex, P. Lucain, F. Turjman, Y. Berthezène, J.C. Froment, and P. Trouillas. Diffusion-weighted MRI in acute mutism. Cerebrovasc Dis, 10:155-157, 2000.


  40. [DERE-00a] L. Derex, N. Nighoghossian, F. Turjman, M. Hermier, J. Honnorat, P.H. Neuschwander, and P. Trouillas. Intravenous tPA in acute ischemic stroke related to internal carotid artery dissection. Neurology, (54):2159-2161, 2000.


  41. [TROU-00] P. Trouillas, L. Derex, N. Nighoghossian, J. Honnorat, W. Li, P.H. Neuschwander, G. Riche, Y. Berthezène, F. Turjman, and J.C. Froment. rtPA intravenous thrombolysis in anterior choroidal artery territory stroke. Neurology, (54):666-673, 2000.


  42. [NIGH-99a] N. Nighoghossian, Y. Berthezène, P. Adeleine, M. Wiart, J. Damien, L. Derex, R. Itti, J.C. Froment, and P. Trouillas. Effects of subcortical cerebrovascular lesions on cortical hemodynamic parameters assessed by perfusion magnetic resonance imaging. Cerebrovasc Dis, 9:136-141, 1999.


  43. [NIGH-99b] N. Nighoghossian, L. Derex, F. Turjman, J. Honnorat, P. Lucain, Y. Berthezène, F. Artru, J.C. Froment, and P. Trouillas. Hyperacute diffusion-weighted MRI in basilar occlusion treated with intra-arterial t-PA. Cerebrovasc Dis, 9:351-354, 1999.


  44. [THOB-99] S. Thobois, N. Nighoghossian, J.F. Mazoyer, J. Honnorat, L. Derex, J.C. Froment, and P. Trouillas. Thrombophlébite corticale et anomalie veineuse du développement. Rev Neurol, (155):48-50, 1999.


  45. [BERT-98b] Y. Berthezène, N. Nighoghossian, J. Damien, L. Derex, P. Trouillas, and J.C. Froment. Effects of thalamic hemorrhage on cortical hemodynamic parameters assessed by perfusion MR imaging. J Neurosci, 157:67-72, 1998.


  46. [TROU-98] P. Trouillas, N. Nighoghossian, L. Derex, P. Adeleine, J. Honnorat, P. H. Neuschwander, G. Riche, J.C. Getenet, W. Li, J.C. Froment, F. Turjman, D. Malicier, G. Fournier, A. I. Gabry, X. Ledoux, Y. Berthezène, P. French, and M. Dechavanne. Thrombolysis with intravenous rtPA in a series of 100 cases of acute carotid territory stroke : determination of etiological, topographic, and radiological outcome factors. Stroke, 29(12):2529-2540, 1998.


  47. [PEYS-03] S. Peysson, N. Nighoghossian, L. Derex, A. Jouvet, M. Hermier, and P. Trouillas. Cerebral amyloid angiopathy revealed by transient ischemic events: contribution of MRI to diagnosis and pathophysiology study. Rev Neurol, 159(2):203-205, 1993.


Communications Proceedings
  1. [NIGH-07] N. Nighoghossian, M. Wiart, Y. Berthezène, T.H. Cho, S. Cakmak, L. Derex, J.C. Froment, P. Trouillas, and M. Hermier. Assessment of inflammatory response after ischemic stroke: Ultrasmall particles of iron oxide enhanced magnetic resonance study in patients. In Stroke, volume 38, San Francisco, California, USA, pages 566-567, 2007.


  2. [NIGH-04] N. Nighoghossian, M. Hermier, L. Derex, P. Adeleine, M. Wiart, Y. Berthezène, J.C. Froment, J. Honnorat, F. Philippeau, and P. Trouillas. Hypointense transcerebral veins at T2*-weighted MRI: A marker of hemorrhagic transformation risk in patients treated by intravenous tissue plasminogen activator. In Stroke, volume 35, San Diego, California, USA, pages 237, 2004.


  3. [HERM-03c] M. Hermier, N. Nighoghossian, P. Adeleine, L Derex, M. Wiart, Y. Berthezène, J.B. Pialat, F. Cotton, P. Trouillas, and J.C. Froment. Les veines transcérébrales hypointenses en T2* : un marqueur du risque de transformation hémorragique des accidents ischémiques aigus traités thrombolyse intraveineuse. In Journées Françaises de Radiologie, volume 84 of J Radiol, Paris, France, pages 1192, 2003.


  4. [NIGH-03c] N. Nighoghossian, M. Hermier, L. Derex, P. Dardel, Y. Berthezène, J.C. Froment, and P. Trouillas. MRI prediction of stroke outcome in patients treated by intravenous t-PA. In 55th Meeting of American Academy of Neurology, volume 60 of Neurology, Honolulu, Hawaii, USA, pages A308-A309, 2003.


  5. [BELO-02] M. Belo, N. Nighoghossian, L. Derex, M. Hermier, J.C. Froment, F. Turjman, and P. Trouillas. Late thrombolysis at 18 hour by abciximab in acute stroke. A multimodal MRI assessment. In 7th International Symposium on Thrombolysis and Acute Stroke Therapy, Lyon, France, pages 73, 2002.


  6. [DERE-02b] L. Derex, M. Hermier, P. Adeleine, J. Honnorat, Y. Berthezène, J.C. Froment, N. Nighoghossian, and P. Trouillas. Usefulness of T2*-weighted MRI sequences before intravenous tPA for acute ischemic stroke. In 7th International Symposium on Thrombolysis and Acute Stroke Therapy, Lyon, France, pages 83, 2002.


  7. [HERM-02b] M. Hermier, N. Nighoghossian, P. Adeleine, Y. Berthezène, L. Derex, H. Yilmaz, J.F. Dugor, P. Dardel, F. Philippeau, P. Trouillas, and J.C. Froment. Predictive value of early MRI arterial recanalization and late infarct volume in patients with acute carotid artery territory stroke. In Symposium Neororadiologicum, volume 29 of J Neuroradiology, Paris, France, pages 88, 2002.


  8. [NIGH-02d] N. Nighoghossian, M. Hermier, P. Adeleine, L. Derex, Y. Berthezène, J.C. Froment, and P. Trouillas. Thrombolyse intraveineuse des infarctus cérébraux. Facteurs prédictifs de la réponse thérapeutique. In 7e Journées de la Société Française Neurovasculaire SFNV 2002, Paris, France, 2002.


  9. [NIGH-02c] N. Nighoghossian, M. Hermier, P. Adeleine, L. Derex, F. Philippeau, J.F. Dugor, H. Yilmaz, J. Honnorat, J.C. Froment, and P. Trouillas. Magnetic resonance imaging prediction of stroke outcome. A pre- and post-thrombolytic therapy study. In 7th International Symposium on Thrombolysis and Acute Stroke Therapy, Lyon, France, pages 34, 2002.


  10. [NIGH-02b] N. Nighoghossian, M. Hermier, J.F. Dugor, P. Adeleine, L. Derex, J.C. Froment, K. Blanc-Lasserre, and P. Trouillas. Old microbleeds may increase the risk of acute hemorrhagic transformation in stroke patients: a gradient-echo T2*-weighted brain MRI study. In 27th International Stroke Conference, Some City, Some Country, 2002.


  11. [PHIL-02] F. Philippeau, P. Adeleine, L. Derex, M. Hermier, N. Nighoghossian, J. Honnorat, and P. Trouillas. Search for clinical and CT features predictive of intracerebral hemorrhage after IV t-PA for acute carotid territory stroke. Data from Lyon thrombolysis registry (150 cases). In 7th International Symposium on Thrombolysis and Acute Stroke Therapy, Lyon, France, pages 72, 2002.


  12. [NIGH-01b] N. Nighoghossian, L. Derex, M. Hermier, P. Adeleine, J.C. Froment, and P. Trouillas. Early detection of cerebral arterial occlusion on magnetic resonance angiography. Predictive value of baseline NIHSS score and impact of clot detection on neurological outcome. In 10th European Stroke Conference, volume 11 of Cerebrovasc Dis, Lisboa, Portugal, pages 56, 2001.


  13. [NIGH-01c] N. Nighoghossian, L. Derex, M. Hermier, Y. Berthezène, J.C. Froment, and P. Trouillas. Early diagnosis of intracranial hemorrhage after t-PA with T2* gradient-echo MRI. In 10th European Stroke Conference, volume 11 of Cerebrovasc Dis, Lisboa, Portugal, pages 119, 2001.


  14. [DERE-00b] L. Derex, N. Nighoghossian, M. Hermier, F. Turjman, and J.C. Froment. Intravenous TPA in acute ischemic stroke related to internal carotid artery dissection. In 25th International Stroke Conference, New Orleans, Louisiana, pages 307, 2000.



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